EE03758B1 - Lahustuvad oksiidid bioloogiliseks kasutamiseks - Google Patents

Lahustuvad oksiidid bioloogiliseks kasutamiseks

Info

Publication number
EE03758B1
EE03758B1 EE9800418A EE9800418A EE03758B1 EE 03758 B1 EE03758 B1 EE 03758B1 EE 9800418 A EE9800418 A EE 9800418A EE 9800418 A EE9800418 A EE 9800418A EE 03758 B1 EE03758 B1 EE 03758B1
Authority
EE
Estonia
Prior art keywords
xerogel
silica
biological use
soluble oxides
gel
Prior art date
Application number
EE9800418A
Other languages
English (en)
Estonian (et)
Other versions
EE9800418A (et
Inventor
Oiva Antero Kurkela Kauko
Ahola Manja
Fagerholm Heidi
Kangasniemi Ilkka
Kiesvaara Juha
Kortesuo Pirjo
Saarinen Niilo
Yli-Urpo Antti
Original Assignee
Orion Corporation
Bioxid Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26691266&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE03758(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orion Corporation, Bioxid Oy filed Critical Orion Corporation
Publication of EE9800418A publication Critical patent/EE9800418A/xx
Publication of EE03758B1 publication Critical patent/EE03758B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0031—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0042—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00—Silicon; Compounds thereof
    • C01B33/113—Silicon oxides; Hydrates thereof
    • C01B33/12—Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • C01B33/16—Preparation of silica xerogels
    • C01B33/163—Preparation of silica xerogels by hydrolysis of organosilicon compounds, e.g. ethyl orthosilicate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43—Hormones, e.g. dexamethasone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/64—Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Inorganic Chemistry (AREA)
  • Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Ceramic Engineering (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Silicon Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EE9800418A 1996-05-29 1997-05-29 Lahustuvad oksiidid bioloogiliseks kasutamiseks EE03758B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1857596P 1996-05-29 1996-05-29
US4242397P 1997-03-27 1997-03-27
PCT/FI1997/000330 WO1997045367A1 (en) 1996-05-29 1997-05-29 Dissolvable oxides for biological applications

Publications (2)

Publication Number Publication Date
EE9800418A EE9800418A (et) 1999-10-15
EE03758B1 true EE03758B1 (et) 2002-06-17

Family

ID=26691266

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800418A EE03758B1 (et) 1996-05-29 1997-05-29 Lahustuvad oksiidid bioloogiliseks kasutamiseks

Country Status (18)

Country Link
EP (2) EP1618896A3 (zh)
JP (1) JP4322315B2 (zh)
CN (1) CN1103320C (zh)
AT (1) ATE301102T1 (zh)
AU (1) AU738176B2 (zh)
CA (1) CA2257172C (zh)
CZ (1) CZ297042B6 (zh)
DE (1) DE69733889T3 (zh)
DK (1) DK0906243T4 (zh)
EE (1) EE03758B1 (zh)
ES (1) ES2244998T5 (zh)
HU (1) HU227939B1 (zh)
NO (1) NO328711B1 (zh)
NZ (1) NZ332968A (zh)
PL (1) PL330191A1 (zh)
RU (1) RU2208582C2 (zh)
SK (1) SK284193B6 (zh)
WO (1) WO1997045367A1 (zh)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI980032A0 (fi) * 1998-01-09 1998-01-09 Heikki Matti Eemeli Rauvala Ny anvaendning av en heparin bindande, med tillvaext foerknippad molekyl
FI109332B (fi) 1998-12-17 2002-07-15 Orion Yhtymae Oyj Toremifeenin liukoisia koostumuksia
JP4812167B2 (ja) 1999-02-12 2011-11-09 モレキュラー インサイト ファーマスーティカルズ インコーポレイテッド 薬物輸送用マトリックス、ならびにその作成方法および使用方法
PL204627B1 (pl) * 1999-02-22 2010-01-29 Bayer Innovation Gmbh Sposób regulowania stopnia biologicznej degradacji przędzonego z zolu krzemionkowego włókna krzemionkowego, włókno krzemionkowe i jego zastosowanie
FI19991806A (fi) 1999-08-25 2001-02-26 Yli Urpo Antti Uusia koostumuksia biologisesti aktiivisen aineen säädettyyn vapauttamiseen, ja niiden valmistus
US6632412B2 (en) * 1999-12-01 2003-10-14 Timo Peltola Bioactive sol-gel derived silica fibers and methods for their preparation
AUPQ573300A0 (en) 2000-02-21 2000-03-16 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
US7758888B2 (en) 2000-04-21 2010-07-20 Sol-Gel Technologies Ltd. Composition exhibiting enhanced formulation stability and delivery of topical active ingredients
BR0110600A (pt) 2000-04-21 2003-04-15 Sol Gel Technologies Ltd Composição terapêutica ou cosmética para aplicação tópica e processo para preparação de micro-cápsulas de sol-gel
WO2002080977A1 (en) * 2001-04-04 2002-10-17 Delsitech Oy Biodegradable carrier and method for preparation thereof
JP4199545B2 (ja) * 2001-04-27 2008-12-17 ビボキシド オサケユイチア 軟組織付着の改善方法、および移植片作製のための該方法の使用
US8580291B2 (en) * 2002-03-15 2013-11-12 The Trustees Of The University Of Pennsylvania Fibrous composite for tissue engineering
AU2004207813B8 (en) * 2003-01-24 2010-04-22 Health Research, Inc. Use of photodynamic therapy therapeutic agents entrapped in ceramic nanoparticles
CA2533406C (en) 2003-07-31 2013-01-22 Sol-Gel Technologies Ltd. Microcapsules loaded with active ingredients and a method for their preparation
US10149825B2 (en) 2004-02-27 2018-12-11 Delsitech Oy Method for preparing adjustably bioresorbable sol-gel derived SiO2
GB0420016D0 (en) 2004-09-09 2004-10-13 Leuven K U Res & Dev Controlled release oral delivery system
JP4006002B2 (ja) * 2004-11-26 2007-11-14 キヤノン株式会社 Ｄｎａ担持繊維及びｄｎａ担持繊維シート並びにこれらの製造方法
EP1919606A2 (en) 2005-08-02 2008-05-14 Sol-Gel Technologies Ltd. Metal oxide coating of water insoluble ingredients
WO2007036939A2 (en) 2005-09-27 2007-04-05 Sol-Gel Technologies Ltd. Methods for crop protection
EP2021283B1 (en) 2006-05-04 2015-07-08 Agency for Science, Technology and Research Mechanically reversible gel
US8343514B2 (en) * 2006-06-06 2013-01-01 Universidad Autonome Metropolitana Sol-gel nanostructured titania reservoirs for use in the controlled release of drugs in the central nervous system and method of synthesis
EP2077821B1 (en) 2006-10-12 2019-08-14 The University Of Queensland Compositions and methods for modulating immune responses
DE102007061873A1 (de) 2007-01-15 2008-07-17 Bayer Innovation Gmbh Kieselsol-Material zur Herstellung von biologisch degradierbaren und/oder resorbierbaren Kieselgel-Materialien dessen Herstellung und Verwendung
FI20070174A0 (fi) * 2007-02-28 2007-02-28 Delsitech Oy Menetelmä silikakoostumusten valmistamiseksi, silikakoostumukset ja niiden käytöt
JP5344417B2 (ja) * 2007-04-17 2013-11-20 国立大学法人群馬大学 水油界面を利用した薬物−シリカ封入体の製造法
DE102007026043B4 (de) * 2007-06-04 2018-08-16 Jiangsu Synecoun Medical Technology Co., Ltd. Nicht-toxisches Polyethoxysiloxan-Material zur Herstellung von biologisch resorbierbares und/oder bioaktives Polyethoxysiloxan-Material enthaltenden Artikeln, dessen Herstellung und Verwendung
DE102007061874A1 (de) * 2007-12-19 2009-06-25 Bayer Innovation Gmbh Nicht-toxisches Polysiloxan-Material zur Herstellung von biologisch resorbierbaren und/oder bioaktiven Polysiloxan-Material enthaltenden Artikeln, dessen Herstellung und Verwendung
DE102008033327A1 (de) * 2008-07-16 2010-01-21 Bayer Innovation Gmbh Kieselsol-Material mit mindestens einem therapeutisch aktiven Wirkstoff zur Herstellung von biologisch degradierbaren und/oder resorbierbaren Kieselgel-Materialien für die Humanmedizin und/oder Medizintechnik
DE102009053782A1 (de) * 2009-11-19 2011-06-01 BSH Bosch und Siemens Hausgeräte GmbH Poröses SiO2-Xerogel mit charakteristischer Porengröße, dessen trocknungsstabile Vorstufen und dessen Anwendung
DE102009053784A1 (de) * 2009-11-19 2011-05-26 BSH Bosch und Siemens Hausgeräte GmbH Verfahren zur Herstellung eines porösen SiO2-Xerogels mit charakteristischer Porengröße durch ein Bottom-Up-Verfahren über eine Vorstufe mit organischen Festkörperskelettstützen
US8901185B2 (en) * 2010-04-12 2014-12-02 Universite Claude Bernard Lyon I Hybrid organic-inorganic material constituted by a silica network having photochromic agents and optical power limiting agents as a doping agent in the material
EP2417982A1 (en) * 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
DE102010034695A1 (de) * 2010-08-18 2012-02-23 Gesellschaft zur Förderung von Medizin-, Bio- und Umwelttechnologien e.V. Xerogele mit homogen eingebetteten Lebensmittelzusätzen und Verfahren zur ihrer Herstellung
BR112013010926A2 (pt) 2010-11-01 2016-08-23 Univ Technology Sidney agentes imunomoduladores e seus usos
SG11201403094TA (en) 2011-12-11 2014-10-30 Recro Pharma Inc Intranasal dexmedetomidine compositions and methods of use thereof
HUE051406T2 (hu) 2012-11-14 2021-03-01 Grace W R & Co Biológiailag aktív anyagot és rendezetlen szervetlen oxidot tartalmazó kompozíciók
US9687465B2 (en) 2012-11-27 2017-06-27 Sol-Gel Technologies Ltd. Compositions for the treatment of rosacea
CA2912483C (en) * 2013-06-24 2021-06-15 Delsitech Oy Silica hydrogel composite
CN104546804A (zh) * 2013-10-09 2015-04-29 上海现代药物制剂工程研究中心有限公司 三维网状立体构型的透皮给药制剂及其制备方法
EP3365020B1 (en) 2015-10-22 2019-07-17 DelSiTech Oy Hydrogel composite depot formulation
GR1010001B (el) * 2019-12-30 2021-05-12 Πυρογενεσις Αβεε Υδρογελες και ξηρογελες φορεις δραστικων συστατικων αποτελουμενες απο δενδριτικα πολυμερη και πυριτια για εφαρμογες επικαλυψης σε στερεα υποστρωματα

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846537A (en) * 1972-08-21 1974-11-05 Monsanto Co Process of preparing silica xerogels
JPH0764543B2 (ja) * 1987-07-24 1995-07-12 富士デヴィソン化学株式会社 球状シリカ及びその製法
IT1216570B (it) * 1988-04-08 1990-03-08 Vectorpharma Int Composizione farmaceutiche a rilascio controllato e procedimento per la loro preparazione.
US5200334A (en) * 1991-08-13 1993-04-06 The Regents Of The University Of California Sol-gel encapsulated enzyme
DE4422912A1 (de) * 1994-06-30 1996-01-11 Hoechst Ag Xerogele, Verfahren zu ihrer Herstellung, sowie ihre Verwendung
US5591453A (en) * 1994-07-27 1997-01-07 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses

Also Published As

Publication number Publication date
AU2964197A (en) 1998-01-05
HUP9903865A1 (hu) 2000-04-28
EP1618896A2 (en) 2006-01-25
AU738176B2 (en) 2001-09-13
NO328711B1 (no) 2010-05-03
RU2208582C2 (ru) 2003-07-20
EE9800418A (et) 1999-10-15
ES2244998T5 (es) 2009-06-15
SK164298A3 (en) 1999-11-08
DK0906243T3 (da) 2005-10-03
EP0906243B1 (en) 2005-08-03
CZ384598A3 (cs) 1999-07-14
EP0906243B2 (en) 2009-04-01
CZ297042B6 (cs) 2006-08-16
HUP9903865A3 (en) 2000-06-28
CN1219919A (zh) 1999-06-16
JP2001509122A (ja) 2001-07-10
EP0906243A1 (en) 1999-04-07
CA2257172A1 (en) 1997-12-04
DE69733889T2 (de) 2006-04-13
ATE301102T1 (de) 2005-08-15
ES2244998T3 (es) 2005-12-16
PL330191A1 (en) 1999-04-26
CA2257172C (en) 2005-04-12
CN1103320C (zh) 2003-03-19
EP1618896A3 (en) 2010-07-14
HU227939B1 (en) 2012-06-28
NO985534L (no) 1999-01-26
NO985534D0 (no) 1998-11-27
WO1997045367A1 (en) 1997-12-04
DE69733889T3 (de) 2009-10-22
NZ332968A (en) 2000-08-25
SK284193B6 (sk) 2004-10-05
DE69733889D1 (de) 2005-09-08
DK0906243T4 (da) 2009-06-08
JP4322315B2 (ja) 2009-08-26

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