ATE301102T1 - Lösliche oxide für biologische anwendungen - Google Patents

Lösliche oxide für biologische anwendungen

Info

Publication number
ATE301102T1
ATE301102T1 AT97924045T AT97924045T ATE301102T1 AT E301102 T1 ATE301102 T1 AT E301102T1 AT 97924045 T AT97924045 T AT 97924045T AT 97924045 T AT97924045 T AT 97924045T AT E301102 T1 ATE301102 T1 AT E301102T1
Authority
AT
Austria
Prior art keywords
biological applications
soluble oxides
xerogel
silica
gel
Prior art date
Application number
AT97924045T
Other languages
English (en)
Inventor
Manja Ahola
Heidi Fagerholm
Ilkka Kangasniemi
Juha Kiesvaara
Pirjo Kortesuo
Kauko Kurkela
Niilo Saarinen
Antti Yli-Urpo
Original Assignee
Delsitech Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26691266&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE301102(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Delsitech Oy filed Critical Delsitech Oy
Application granted granted Critical
Publication of ATE301102T1 publication Critical patent/ATE301102T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0031—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0042—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00—Silicon; Compounds thereof
    • C01B33/113—Silicon oxides; Hydrates thereof
    • C01B33/12—Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • C01B33/16—Preparation of silica xerogels
    • C01B33/163—Preparation of silica xerogels by hydrolysis of organosilicon compounds, e.g. ethyl orthosilicate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43—Hormones, e.g. dexamethasone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/64—Animal cells
AT97924045T 1996-05-29 1997-05-29 Lösliche oxide für biologische anwendungen ATE301102T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1857596P 1996-05-29 1996-05-29
US4242397P 1997-03-27 1997-03-27
PCT/FI1997/000330 WO1997045367A1 (en) 1996-05-29 1997-05-29 Dissolvable oxides for biological applications

Publications (1)

Publication Number Publication Date
ATE301102T1 true ATE301102T1 (de) 2005-08-15

Family

ID=26691266

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97924045T ATE301102T1 (de) 1996-05-29 1997-05-29 Lösliche oxide für biologische anwendungen

Country Status (18)

Country Link
EP (2) EP0906243B2 (de)
JP (1) JP4322315B2 (de)
CN (1) CN1103320C (de)
AT (1) ATE301102T1 (de)
AU (1) AU738176B2 (de)
CA (1) CA2257172C (de)
CZ (1) CZ297042B6 (de)
DE (1) DE69733889T3 (de)
DK (1) DK0906243T4 (de)
EE (1) EE03758B1 (de)
ES (1) ES2244998T5 (de)
HU (1) HU227939B1 (de)
NO (1) NO328711B1 (de)
NZ (1) NZ332968A (de)
PL (1) PL330191A1 (de)
RU (1) RU2208582C2 (de)
SK (1) SK284193B6 (de)
WO (1) WO1997045367A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI980032A0 (fi) * 1998-01-09 1998-01-09 Heikki Matti Eemeli Rauvala Ny anvaendning av en heparin bindande, med tillvaext foerknippad molekyl
FI109332B (fi) 1998-12-17 2002-07-15 Orion Yhtymae Oyj Toremifeenin liukoisia koostumuksia
AU772153B2 (en) 1999-02-12 2004-04-08 Molecular Insight Pharmaceuticals, Inc. Matrices for drug delivery and methods for making and using the same
HUP0200277A3 (en) * 1999-02-22 2004-03-29 Bioxid Oy Biodegradable ceramic fibres from silica sols
FI19991806A (fi) * 1999-08-25 2001-02-26 Yli Urpo Antti Uusia koostumuksia biologisesti aktiivisen aineen säädettyyn vapauttamiseen, ja niiden valmistus
US6632412B2 (en) * 1999-12-01 2003-10-14 Timo Peltola Bioactive sol-gel derived silica fibers and methods for their preparation
AUPQ573300A0 (en) 2000-02-21 2000-03-16 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
US7758888B2 (en) 2000-04-21 2010-07-20 Sol-Gel Technologies Ltd. Composition exhibiting enhanced formulation stability and delivery of topical active ingredients
CA2406008C (en) 2000-04-21 2011-03-15 Sol-Gel Technologies Ltd. Composition exhibiting enhanced formulation stability and delivery of topical active ingredients
US7485318B2 (en) 2001-04-04 2009-02-03 Delsitech Oy Biodegradable carrier and method for preparation thereof
US7527804B2 (en) * 2001-04-27 2009-05-05 Vivoxid Oy Method for improvement of soft tissue attachment and implants making use of said method
WO2005007802A2 (en) * 2002-03-15 2005-01-27 The Trustees Of The University Of Pennsylvania Fibrous composite for tissue engineering
AU2004207813B8 (en) * 2003-01-24 2010-04-22 Health Research, Inc. Use of photodynamic therapy therapeutic agents entrapped in ceramic nanoparticles
US8110284B2 (en) 2003-07-31 2012-02-07 Sol-Gel Technologies Ltd. Microcapsules loaded with active ingredients and a method for their preparation
CA2555179A1 (en) * 2004-02-27 2005-09-09 Delsitech Oy Method for preparing adjustably bioresorbable sol-gel derived sio2
GB0420016D0 (en) 2004-09-09 2004-10-13 Leuven K U Res & Dev Controlled release oral delivery system
JP4006002B2 (ja) * 2004-11-26 2007-11-14 キヤノン株式会社 Ｄｎａ担持繊維及びｄｎａ担持繊維シート並びにこれらの製造方法
WO2007015243A2 (en) 2005-08-02 2007-02-08 Sol-Gel Technologies Ltd. Metal oxide coating of water insoluble ingredients
US20080254082A1 (en) 2005-09-27 2008-10-16 Sol-Gel Technologies Ltd. Methods for Crop Protection
WO2007129991A1 (en) 2006-05-04 2007-11-15 Agency For Science Technology And Research Mechanically reversible gel
WO2007141590A1 (en) * 2006-06-06 2007-12-13 Universidad Autonoma Metropolitana Sol-gel nanostructured titania reservoirs for use in the controlled release of drugs in the central nervous system and method of synthesis
JP2010505883A (ja) 2006-10-12 2010-02-25 ザ ユニバーシティー オブ クイーンズランド 免疫応答を調節するための組成物および方法
DE102007061873A1 (de) * 2007-01-15 2008-07-17 Bayer Innovation Gmbh Kieselsol-Material zur Herstellung von biologisch degradierbaren und/oder resorbierbaren Kieselgel-Materialien dessen Herstellung und Verwendung
FI20070174A0 (fi) * 2007-02-28 2007-02-28 Delsitech Oy Menetelmä silikakoostumusten valmistamiseksi, silikakoostumukset ja niiden käytöt
JP5344417B2 (ja) * 2007-04-17 2013-11-20 国立大学法人群馬大学 水油界面を利用した薬物−シリカ封入体の製造法
DE102007026043B4 (de) * 2007-06-04 2018-08-16 Jiangsu Synecoun Medical Technology Co., Ltd. Nicht-toxisches Polyethoxysiloxan-Material zur Herstellung von biologisch resorbierbares und/oder bioaktives Polyethoxysiloxan-Material enthaltenden Artikeln, dessen Herstellung und Verwendung
DE102007061874A1 (de) * 2007-12-19 2009-06-25 Bayer Innovation Gmbh Nicht-toxisches Polysiloxan-Material zur Herstellung von biologisch resorbierbaren und/oder bioaktiven Polysiloxan-Material enthaltenden Artikeln, dessen Herstellung und Verwendung
DE102008033327A1 (de) * 2008-07-16 2010-01-21 Bayer Innovation Gmbh Kieselsol-Material mit mindestens einem therapeutisch aktiven Wirkstoff zur Herstellung von biologisch degradierbaren und/oder resorbierbaren Kieselgel-Materialien für die Humanmedizin und/oder Medizintechnik
DE102009053784A1 (de) * 2009-11-19 2011-05-26 BSH Bosch und Siemens Hausgeräte GmbH Verfahren zur Herstellung eines porösen SiO2-Xerogels mit charakteristischer Porengröße durch ein Bottom-Up-Verfahren über eine Vorstufe mit organischen Festkörperskelettstützen
DE102009053782A1 (de) * 2009-11-19 2011-06-01 BSH Bosch und Siemens Hausgeräte GmbH Poröses SiO2-Xerogel mit charakteristischer Porengröße, dessen trocknungsstabile Vorstufen und dessen Anwendung
EP2558424B1 (de) * 2010-04-12 2023-06-07 Université Claude Bernard Lyon I Verfahren zur herstellung von hybridmaterialien durch schnelle kondensation eines siliciumorganischen sols
EP2417982A1 (de) * 2010-07-30 2012-02-15 Ferring B.V. Stabilisierung von Gonadotropinen
DE102010034695A1 (de) * 2010-08-18 2012-02-23 Gesellschaft zur Förderung von Medizin-, Bio- und Umwelttechnologien e.V. Xerogele mit homogen eingebetteten Lebensmittelzusätzen und Verfahren zur ihrer Herstellung
AU2011325857A1 (en) 2010-11-01 2013-05-02 University Of Technology, Sydney Immune-modulating agents and uses therefor
PE20142314A1 (es) 2011-12-11 2015-01-23 Recro Pharma Inc Composiciones intranasales de dexmedetomidina y metodos de uso de ellas
KR102237799B1 (ko) 2012-11-14 2021-04-08 더블유.알. 그레이스 앤드 캄파니-콘. 생물학적 활성 물질 및 비-정렬된 무기 산화물을 함유하는 조성물
US9687465B2 (en) 2012-11-27 2017-06-27 Sol-Gel Technologies Ltd. Compositions for the treatment of rosacea
CA2912483C (en) * 2013-06-24 2021-06-15 Delsitech Oy Silica hydrogel composite
CN104546804A (zh) * 2013-10-09 2015-04-29 上海现代药物制剂工程研究中心有限公司 三维网状立体构型的透皮给药制剂及其制备方法
EP3365020B1 (de) 2015-10-22 2019-07-17 DelSiTech Oy Depotformulierung für hydrogelverbund
GR1010001B (el) * 2019-12-30 2021-05-12 Πυρογενεσις Αβεε Υδρογελες και ξηρογελες φορεις δραστικων συστατικων αποτελουμενες απο δενδριτικα πολυμερη και πυριτια για εφαρμογες επικαλυψης σε στερεα υποστρωματα

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846537A (en) * 1972-08-21 1974-11-05 Monsanto Co Process of preparing silica xerogels
JPH0764543B2 (ja) * 1987-07-24 1995-07-12 富士デヴィソン化学株式会社 球状シリカ及びその製法
IT1216570B (it) * 1988-04-08 1990-03-08 Vectorpharma Int Composizione farmaceutiche a rilascio controllato e procedimento per la loro preparazione.
US5200334A (en) * 1991-08-13 1993-04-06 The Regents Of The University Of California Sol-gel encapsulated enzyme
DE4422912A1 (de) * 1994-06-30 1996-01-11 Hoechst Ag Xerogele, Verfahren zu ihrer Herstellung, sowie ihre Verwendung
US5591453A (en) * 1994-07-27 1997-01-07 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses

Also Published As

Publication number Publication date
SK164298A3 (en) 1999-11-08
PL330191A1 (en) 1999-04-26
HU227939B1 (en) 2012-06-28
DK0906243T3 (da) 2005-10-03
CZ384598A3 (cs) 1999-07-14
EP1618896A3 (de) 2010-07-14
EE03758B1 (et) 2002-06-17
RU2208582C2 (ru) 2003-07-20
WO1997045367A1 (en) 1997-12-04
HUP9903865A3 (en) 2000-06-28
EP0906243B1 (de) 2005-08-03
AU2964197A (en) 1998-01-05
AU738176B2 (en) 2001-09-13
CA2257172A1 (en) 1997-12-04
CN1219919A (zh) 1999-06-16
SK284193B6 (sk) 2004-10-05
JP2001509122A (ja) 2001-07-10
DE69733889T3 (de) 2009-10-22
NO328711B1 (no) 2010-05-03
EP1618896A2 (de) 2006-01-25
DK0906243T4 (da) 2009-06-08
CZ297042B6 (cs) 2006-08-16
DE69733889T2 (de) 2006-04-13
CN1103320C (zh) 2003-03-19
HUP9903865A1 (hu) 2000-04-28
CA2257172C (en) 2005-04-12
NO985534L (no) 1999-01-26
DE69733889D1 (de) 2005-09-08
JP4322315B2 (ja) 2009-08-26
EE9800418A (et) 1999-10-15
NZ332968A (en) 2000-08-25
ES2244998T5 (es) 2009-06-15
NO985534D0 (no) 1998-11-27
ES2244998T3 (es) 2005-12-16
EP0906243A1 (de) 1999-04-07
EP0906243B2 (de) 2009-04-01

Similar Documents

Publication Publication Date Title
ATE301102T1 (de) Lösliche oxide für biologische anwendungen
EP0823789A3 (de) Multifrequenz- und Multiprotokoll-Funkgerät
ATE547136T1 (de) Therapievorrichtung für wunden
WO2007011612A3 (en) Wound dressing and methods of making and using the same
WO2001064132A3 (en) Wound dressings with protease-lowering activity
ATE512650T1 (de) Hydrogelwundverband und zugehöriges herstellungs- und benutzungsverfahren
BR9508723A (pt) Implante método de implantação e dispositivo de aplicação
ATE357893T1 (de) Wundverband aus saugfähigem schaumstoff
DK0543868T3 (da) Sårovertrækssystem
WO2002092049A3 (en) System for delivering cosmetics and pharmaceuticals
AU6272199A (en) Surgical dressing with delivery system and method of manufacture
CA2198553A1 (en) Gas diffusion electrodes
EP1607078A3 (de) Pflaster
DE69839940D1 (de) Sauerstoff-abgabe mittel und ihre anwendung
AU5456894A (en) Polysiloxanes having fluoroaliphatic- and carboxyl-containing terminal groups, their preparation, and their use in treatment of fibrous substrates
DE69636507D1 (de) Blutbehälter, sowie Instrument und Gerät zur Abgabe von Blut
DE59807862D1 (de) Selbstklebende fertigbandage zur immobilisation des handgelenks
WO2002051457A3 (en) Removal of targeted proteases with proteinaceous wound dressings containing growth factors
GB2366739A (en) Diaper having reduced relative humidity
AU4416000A (en) Portable integrated circuit device and method for the production thereof
ITRM950439A0 (it) Procedimento ed apparecchio per la erogazione di messaggi in un sistema per comunicazioni.
EP0734143A3 (de) Telekommunikationssystem mit personen/teilnehmerverbundener Identifikation
ZA200005144B (en) Method and system for standardizing delivery, acceptance, and redemption of promotions with various electronic devices.
ATE236705T1 (de) Verminderung von stickoxid
FI964448A0 (fi) Uusi biologisesti aktiivinen peptidi ja sen valmistus

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0906243

Country of ref document: EP

UEP Publication of translation of european patent specification

Ref document number: 0906243

Country of ref document: EP