EE03073B1 - Androstaani derivaadid, mis on 16. asendis asendatud kvaternaarse ammooniumrühmaga, neid sisaldavad farmatseutilised segud ja nende valmistamise protsess - Google Patents

Androstaani derivaadid, mis on 16. asendis asendatud kvaternaarse ammooniumrühmaga, neid sisaldavad farmatseutilised segud ja nende valmistamise protsess

Info

Publication number
EE03073B1
EE03073B1 EE9400067A EE9400067A EE03073B1 EE 03073 B1 EE03073 B1 EE 03073B1 EE 9400067 A EE9400067 A EE 9400067A EE 9400067 A EE9400067 A EE 9400067A EE 03073 B1 EE03073 B1 EE 03073B1
Authority
EE
Estonia
Prior art keywords
quaternary ammonium
ammonium group
preparation
mixtures containing
derivatives substituted
Prior art date
Application number
EE9400067A
Other languages
English (en)
Estonian (et)
Inventor
Tuba Zolt�n
E. Vizi Szilveszter
F. F�ldes Ferenc
Maho S�ndor
Original Assignee
Richter Gedeon Vegy�Szeti Gy�R Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegy�Szeti Gy�R Rt. filed Critical Richter Gedeon Vegy�Szeti Gy�R Rt.
Publication of EE03073B1 publication Critical patent/EE03073B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EE9400067A 1992-11-02 1994-06-29 Androstaani derivaadid, mis on 16. asendis asendatud kvaternaarse ammooniumrühmaga, neid sisaldavad farmatseutilised segud ja nende valmistamise protsess EE03073B1 (et)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9203436A HU210076B (en) 1992-11-02 1992-11-02 Process for producing androstane derivatives substituted with quaternisaeted amino group in 16-position and for producing pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
EE03073B1 true EE03073B1 (et) 1998-02-16

Family

ID=10982503

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9400067A EE03073B1 (et) 1992-11-02 1994-06-29 Androstaani derivaadid, mis on 16. asendis asendatud kvaternaarse ammooniumrühmaga, neid sisaldavad farmatseutilised segud ja nende valmistamise protsess

Country Status (19)

Country Link
US (1) US5591735A (de)
EP (1) EP0608495B1 (de)
JP (1) JP2834651B2 (de)
KR (1) KR0179399B1 (de)
CN (1) CN1041937C (de)
AT (1) ATE154030T1 (de)
AU (1) AU665866B2 (de)
BR (1) BR9304466A (de)
CA (1) CA2108741A1 (de)
DE (1) DE69311295T2 (de)
DK (1) DK0608495T3 (de)
EE (1) EE03073B1 (de)
ES (1) ES2103413T3 (de)
GR (1) GR3024011T3 (de)
HU (1) HU210076B (de)
IL (1) IL107331A (de)
NZ (1) NZ248956A (de)
RU (1) RU2124021C1 (de)
UA (1) UA27230C2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010049620A1 (en) * 2000-02-29 2001-12-06 Blasko John P. Privacy-protected targeting system
US20020123928A1 (en) * 2001-01-11 2002-09-05 Eldering Charles A. Targeting ads to subscribers based on privacy-protected subscriber profiles
US7200804B1 (en) * 1998-12-08 2007-04-03 Yodlee.Com, Inc. Method and apparatus for providing automation to an internet navigation application
KR20070085703A (ko) * 2005-09-13 2007-08-27 시코르, 인크. 로큐로늄 브로마이드의 합성 방법
CN102675402A (zh) * 2012-05-16 2012-09-19 武汉大学 4，16β-二胺基甾体季铵盐衍生物及其制备方法和应用
CN109053855B (zh) * 2018-10-08 2020-02-14 台州仙琚药业有限公司 一种16β-四氢吡咯基雄甾-2α-环氧-17-酮的合成方法
CN116925171B (zh) * 2023-07-10 2025-06-27 时森海(杭州)医药科技有限公司 含环丙甲基甾体类季铵盐化合物、中间体及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
HU165600B (de) * 1972-07-27 1974-09-28
US4177190A (en) * 1975-08-01 1979-12-04 Richter Gedeon Vegyeszeti Gyar Rt. Diamino-androstanes and a process for the preparation of the said compounds
ATE921T1 (de) * 1978-09-05 1982-05-15 Akzo N.V. Saeureadditionssalze von 2-beta, 16-beta-bis-piperidino-an drostan-16-beta-monoquaternaeren ammoniumderivaten und diese enthaltende pharmazeutische zusammensetzungen.
DE3315324A1 (de) * 1983-04-25 1984-10-31 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von 17(alpha)-(br oder j)-ethinyl-17ss-or-steroiden
HU195972B (en) * 1985-07-01 1988-08-29 Richter Gedeon Vegyeszet Process for producing new diamino-androstane derivatives and pharmaceutical compositions containing them
GB8708886D0 (en) * 1987-04-14 1987-05-20 Akzo Nv 2beta-morpholino-androstane derivatives
GB8709565D0 (en) * 1987-04-23 1987-05-28 Akzo Nv 2beta,16beta-diaminoandrostanes
GB8804579D0 (en) * 1988-02-26 1988-03-30 Akzo Nv Novel 16-homo-piperidino-androstane derivatives & processes for their preparation

Also Published As

Publication number Publication date
AU4900593A (en) 1995-06-08
AU665866B2 (en) 1996-01-18
ES2103413T3 (es) 1997-09-16
JP2834651B2 (ja) 1998-12-09
HUT66162A (en) 1994-09-28
GR3024011T3 (en) 1997-10-31
KR940011476A (ko) 1994-06-21
EP0608495A3 (en) 1995-12-20
IL107331A (en) 1998-12-06
CA2108741A1 (en) 1994-05-03
DE69311295D1 (de) 1997-07-10
EP0608495A2 (de) 1994-08-03
KR0179399B1 (ko) 1999-04-01
UA27230C2 (uk) 2000-08-15
US5591735A (en) 1997-01-07
BR9304466A (pt) 1994-06-14
CN1041937C (zh) 1999-02-03
DE69311295T2 (de) 1997-10-30
DK0608495T3 (da) 1997-08-04
HU9203436D0 (en) 1993-01-28
NZ248956A (en) 1995-08-28
RU2124021C1 (ru) 1998-12-27
EP0608495B1 (de) 1997-06-04
HU210076B (en) 1995-01-30
JPH06192288A (ja) 1994-07-12
ATE154030T1 (de) 1997-06-15
IL107331A0 (en) 1994-01-25
CN1090852A (zh) 1994-08-17

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Legal Events

Date Code Title Description
MM4A Lapsed by not paying the annual fees

Effective date: 20010629