ECSP992959A - BIS-AMINOMETIL CARBONYL PROTEASE INHIBITORS - Google Patents
BIS-AMINOMETIL CARBONYL PROTEASE INHIBITORSInfo
- Publication number
- ECSP992959A ECSP992959A ECSP992959A ECSP992959A EC SP992959 A ECSP992959 A EC SP992959A EC SP992959 A ECSP992959 A EC SP992959A EC SP992959 A ECSP992959 A EC SP992959A
- Authority
- EC
- Ecuador
- Prior art keywords
- diseases
- protease inhibitors
- bis
- aminometil
- cartilage
- Prior art date
Links
Abstract
La presente invención proporciona inhibidores de proteasa de bis-aminometil-carbonilo y sales, hidratos o solvatos de los mismos aceptables farmacéuticamente, que inhiben proteasas, incluyendo la captesina K, composiciones farmacéuticas de tales compuestos, y métodos para tratar enfermedades de una excesiva pérdida ósea o degradación de cartilago o de matriz, incluyendo osteoporosis; enfermedades gingivales incluyendo gingivitis y periodontitis; artritis más especificamente osteoartritis y artritis reumatoide; enfermedad de paget; hipercalcemia de enfermedades malignas; y enfermedades óseas metabólicas, que comprende inhibir dicha pérdida de hueso o dicha excesiva degradación de cartilago o de matriz administrando a un paciente que lo necesite un compuesto según la presente invención.The present invention provides bis-aminomethyl carbonyl protease inhibitors and pharmaceutically acceptable salts, hydrates or solvates thereof, which inhibit proteases, including captesin K, pharmaceutical compositions of such compounds, and methods of treating diseases of excessive bone loss. or cartilage or matrix degradation, including osteoporosis; gingival diseases including gingivitis and periodontitis; arthritis more specifically osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignant diseases; and metabolic bone diseases, which comprises inhibiting said bone loss or said excessive cartilage or matrix degradation by administering to a patient in need a compound according to the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP992959 ECSP992959A (en) | 1999-05-20 | 1999-05-20 | BIS-AMINOMETIL CARBONYL PROTEASE INHIBITORS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP992959 ECSP992959A (en) | 1999-05-20 | 1999-05-20 | BIS-AMINOMETIL CARBONYL PROTEASE INHIBITORS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP992959A true ECSP992959A (en) | 1999-10-06 |
Family
ID=42043948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP992959 ECSP992959A (en) | 1999-05-20 | 1999-05-20 | BIS-AMINOMETIL CARBONYL PROTEASE INHIBITORS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP992959A (en) |
-
1999
- 1999-05-20 EC ECSP992959 patent/ECSP992959A/en unknown
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