ECSP003353A - PROTEASE INHIBITORS IX - Google Patents
PROTEASE INHIBITORS IXInfo
- Publication number
- ECSP003353A ECSP003353A ECSP003353A ECSP003353A EC SP003353 A ECSP003353 A EC SP003353A EC SP003353 A ECSP003353 A EC SP003353A EC SP003353 A ECSP003353 A EC SP003353A
- Authority
- EC
- Ecuador
- Prior art keywords
- excessive
- compounds
- disease
- matrix degradation
- present
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
El presente invento proporciona inhibidores de proteasas con estructura de éteres anulares de 7 14 miembros y sales, hidratos y solvatos farmacéuticamente aceptables de los mismos, que inhiben proteasa, incluyendo la captesina K composiciones framacéuticas de dichos compuestos: nuevos productos intermedios de dichos compuestos y métodos para tratar enfermedades por una excesiva pérdida ósea o una excesiva degradación carrilaginosa o matricial, incluyendo osteoporosis, enfermedades gingivales que incluyen gingivitis y periodontitis, artritis, más especificamente osteoartritis y artritis reumatoide, enfermedad de Paget, hipercalcemia maligna y enfermedad ósea metabólica, que comprenden inhibir dicha pérdida ósea o dicha excesiva degradación cartilaginosa o matricial mediante la administración de un compuesto del presente invencto a un paciente que lo necesita.The present invention provides proteases inhibitors with 7 14-membered ring ether structures and pharmaceutically acceptable salts, hydrates and solvates thereof, which inhibit protease, including captesin K, pharmaceutical compositions of said compounds: novel intermediates of said compounds and methods. to treat diseases of excessive bone loss or excessive carilaginous or matrix degradation, including osteoporosis, gingival diseases including gingivitis and periodontitis, arthritis, more specifically osteoarthritis and rheumatoid arthritis, Paget's disease, malignant hypercalcemia and metabolic bone disease, comprising inhibiting said bone loss or said excessive cartilage or matrix degradation by administering a compound of the present invention to a patient in need.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003353 ECSP003353A (en) | 2000-02-17 | 2000-02-17 | PROTEASE INHIBITORS IX |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003353 ECSP003353A (en) | 2000-02-17 | 2000-02-17 | PROTEASE INHIBITORS IX |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP003353A true ECSP003353A (en) | 2000-06-19 |
Family
ID=42040984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP003353 ECSP003353A (en) | 2000-02-17 | 2000-02-17 | PROTEASE INHIBITORS IX |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP003353A (en) |
-
2000
- 2000-02-17 EC ECSP003353 patent/ECSP003353A/en unknown
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