AR004703A1 - HYDRAZIDIL, BIS-HYDRAZIL AND BIS-AMINOMETIL-CARBONIL, PROTEASE INHIBITORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR INHIBITING PROTEASES, AND USE IN THE PREPARATION OF MEDICINES. - Google Patents

HYDRAZIDIL, BIS-HYDRAZIL AND BIS-AMINOMETIL-CARBONIL, PROTEASE INHIBITORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR INHIBITING PROTEASES, AND USE IN THE PREPARATION OF MEDICINES.

Info

Publication number
AR004703A1
AR004703A1 ARP960104972A ARP960104972A AR004703A1 AR 004703 A1 AR004703 A1 AR 004703A1 AR P960104972 A ARP960104972 A AR P960104972A AR P960104972 A ARP960104972 A AR P960104972A AR 004703 A1 AR004703 A1 AR 004703A1
Authority
AR
Argentina
Prior art keywords
bis
preparation
hydrazidil
hydrazil
aminometil
Prior art date
Application number
ARP960104972A
Other languages
Spanish (es)
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AR004703A1 publication Critical patent/AR004703A1/en

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Compuestos de fórmula (I) que inhiben proteasas, con inclusión de catepsina K, composiciones farmacéuticas que dichos compuestos y uso de dichos compuestosen la preparación de medicamentos para el tratamiento de enfermedades de pérdida ósea odegradación de cartílago o matriz excesivas, con inclusión deosteoporosis; enfermedad gingival con inclusión de gingivitis y periodontitis; artritis, más específicamente, osteoartritis y artritis reumatoide; enfermedadde Paget, hipercalcemia decará cter maligno; y enfermedad metabólica ósea, donde la definición de los sustituyentes son tal como figuran en la memoria.Compounds of formula (I) that inhibit proteases, including cathepsin K, pharmaceutical compositions thereof, and use of said compounds in the preparation of medicaments for the treatment of diseases of excessive bone loss or cartilage or matrix degradation, including deosteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease, hypercalcemia of malignant character; and metabolic bone disease, where the definition of the substituents are as stated in the specification.

ARP960104972A 1995-10-30 1996-10-30 HYDRAZIDIL, BIS-HYDRAZIL AND BIS-AMINOMETIL-CARBONIL, PROTEASE INHIBITORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR INHIBITING PROTEASES, AND USE IN THE PREPARATION OF MEDICINES. AR004703A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US810895P 1995-10-30 1995-10-30
US747395P 1995-11-22 1995-11-22
US899295P 1995-12-21 1995-12-21
US1374896P 1996-03-20 1996-03-20

Publications (1)

Publication Number Publication Date
AR004703A1 true AR004703A1 (en) 1999-03-10

Family

ID=27485695

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960104972A AR004703A1 (en) 1995-10-30 1996-10-30 HYDRAZIDIL, BIS-HYDRAZIL AND BIS-AMINOMETIL-CARBONIL, PROTEASE INHIBITORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR INHIBITING PROTEASES, AND USE IN THE PREPARATION OF MEDICINES.

Country Status (2)

Country Link
AR (1) AR004703A1 (en)
BR (1) BR9612344A (en)

Also Published As

Publication number Publication date
BR9612344A (en) 1999-07-13

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