ECSP982481A - PROTEASE INHIBITORS - Google Patents

PROTEASE INHIBITORS

Info

Publication number
ECSP982481A
ECSP982481A ECSP982481A ECSP982481A EC SP982481 A ECSP982481 A EC SP982481A EC SP982481 A ECSP982481 A EC SP982481A EC SP982481 A ECSP982481 A EC SP982481A
Authority
EC
Ecuador
Prior art keywords
disease
cartilage
excessive
degeneration
present
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Renee Louise Desjarlais
Kevin J Duffy
Daniel Frank Veber
Keenan Richard Mccullock
Stacie Marie Halbert
Evelyne Michaud
Scott Kevin Thompson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP982481 priority Critical patent/ECSP982481A/en
Publication of ECSP982481A publication Critical patent/ECSP982481A/en

Links

Abstract

La presente invención proporciona compuestos que inhiben proteasas, incluyendo catepsina K, composiciones farmacéuticas de tales compuestos, y métodos para tratar enfermedades de excesiva pérdida ósea o degeneración de cartílago o degradación de cartílago o matriz, incluyendo osteoporosis; enfermedad gigival, incluyendo gingivitis y periodontitis; artritis, más especificamente, osteoartritis y artritis reumatoide; enfermedad de Paget; hipercalcemia de enfermedades malignas; y enfermedad ósea metabólica, que comprende inhibir dicha pérdida ósea o degeneración excesiva de cartílago o matriz administrando un compuesto de la presente invención a un paciente con necesidad de ello.The present invention provides compounds that inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods of treating diseases of excessive bone loss or cartilage degeneration or cartilage or matrix degradation, including osteoporosis; gigival disease, including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignant diseases; and metabolic bone disease, which comprises inhibiting said bone loss or excessive cartilage or matrix degeneration by administering a compound of the present invention to a patient in need thereof.

ECSP982481 1998-04-22 1998-04-22 PROTEASE INHIBITORS ECSP982481A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP982481 ECSP982481A (en) 1998-04-22 1998-04-22 PROTEASE INHIBITORS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP982481 ECSP982481A (en) 1998-04-22 1998-04-22 PROTEASE INHIBITORS

Publications (1)

Publication Number Publication Date
ECSP982481A true ECSP982481A (en) 1999-01-19

Family

ID=42043403

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP982481 ECSP982481A (en) 1998-04-22 1998-04-22 PROTEASE INHIBITORS

Country Status (1)

Country Link
EC (1) ECSP982481A (en)

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