ECSP982481A - PROTEASE INHIBITORS - Google Patents
PROTEASE INHIBITORSInfo
- Publication number
- ECSP982481A ECSP982481A ECSP982481A ECSP982481A EC SP982481 A ECSP982481 A EC SP982481A EC SP982481 A ECSP982481 A EC SP982481A EC SP982481 A ECSP982481 A EC SP982481A
- Authority
- EC
- Ecuador
- Prior art keywords
- disease
- cartilage
- excessive
- degeneration
- present
- Prior art date
Links
Abstract
La presente invención proporciona compuestos que inhiben proteasas, incluyendo catepsina K, composiciones farmacéuticas de tales compuestos, y métodos para tratar enfermedades de excesiva pérdida ósea o degeneración de cartílago o degradación de cartílago o matriz, incluyendo osteoporosis; enfermedad gigival, incluyendo gingivitis y periodontitis; artritis, más especificamente, osteoartritis y artritis reumatoide; enfermedad de Paget; hipercalcemia de enfermedades malignas; y enfermedad ósea metabólica, que comprende inhibir dicha pérdida ósea o degeneración excesiva de cartílago o matriz administrando un compuesto de la presente invención a un paciente con necesidad de ello.The present invention provides compounds that inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods of treating diseases of excessive bone loss or cartilage degeneration or cartilage or matrix degradation, including osteoporosis; gigival disease, including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignant diseases; and metabolic bone disease, which comprises inhibiting said bone loss or excessive cartilage or matrix degeneration by administering a compound of the present invention to a patient in need thereof.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ECSP982481 ECSP982481A (en) | 1998-04-22 | 1998-04-22 | PROTEASE INHIBITORS |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ECSP982481 ECSP982481A (en) | 1998-04-22 | 1998-04-22 | PROTEASE INHIBITORS |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP982481A true ECSP982481A (en) | 1999-01-19 |
Family
ID=42043403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ECSP982481 ECSP982481A (en) | 1998-04-22 | 1998-04-22 | PROTEASE INHIBITORS |
Country Status (1)
Country | Link |
---|---|
EC (1) | ECSP982481A (en) |
-
1998
- 1998-04-22 EC ECSP982481 patent/ECSP982481A/en unknown
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