ECSP982493A - PROTEASE INHIBITORS III - Google Patents

PROTEASE INHIBITORS III

Info

Publication number
ECSP982493A
ECSP982493A ECSP982493A ECSP982493A EC SP982493 A ECSP982493 A EC SP982493A EC SP982493 A ECSP982493 A EC SP982493A EC SP982493 A ECSP982493 A EC SP982493A
Authority
EC
Ecuador
Prior art keywords
disease
cartilage
compounds
protease inhibitors
present
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Renee Louise Desjarlais
Daniel Frank Veber
William E Bondinell
Dennis Shinji Yamashita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP982493 priority Critical patent/ECSP982493A/en
Publication of ECSP982493A publication Critical patent/ECSP982493A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

El presente invento crea compuestos que inhiben a proteasas, inclusive catepsina K, composiciones farmacéuticas de dichos compuestos, y métodos para tratar enfermedades con excesiva pérdida de hueso o degradación de cartílago o matriz, inclusive osteoporosis; una enfermedad gingival inclusive gingivitis y periodontitis; artritis, más especificamente osteoartritis y artritis reumatoide; la enfermedad de Paget; hipercalcemia de malignidad; y una enfermedad ósea metabólica, que comprende inhibir dicha pérdida de hueso o dicha degradación de cartílago o matríz por administración, a una persona que necesite de ello, de un compuesto del presente invento.The present invention creates compounds that inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods of treating diseases with excessive bone loss or cartilage or matrix degradation, including osteoporosis; a gingival disease including gingivitis and periodontitis; arthritis, more specifically osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignancy; and a metabolic bone disease, which comprises inhibiting said bone loss or said cartilage or matrix degradation by administration, to a person in need thereof, of a compound of the present invention.

ECSP982493 1998-04-29 1998-04-29 PROTEASE INHIBITORS III ECSP982493A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP982493 ECSP982493A (en) 1998-04-29 1998-04-29 PROTEASE INHIBITORS III

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP982493 ECSP982493A (en) 1998-04-29 1998-04-29 PROTEASE INHIBITORS III

Publications (1)

Publication Number Publication Date
ECSP982493A true ECSP982493A (en) 1999-01-12

Family

ID=42043414

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP982493 ECSP982493A (en) 1998-04-29 1998-04-29 PROTEASE INHIBITORS III

Country Status (1)

Country Link
EC (1) ECSP982493A (en)

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