ECSP23019295A - Composiciones de vacunas multivalentes y usos de las mismas - Google Patents

Composiciones de vacunas multivalentes y usos de las mismas

Info

Publication number
ECSP23019295A
ECSP23019295A ECSENADI202319295A ECDI202319295A ECSP23019295A EC SP23019295 A ECSP23019295 A EC SP23019295A EC SENADI202319295 A ECSENADI202319295 A EC SENADI202319295A EC DI202319295 A ECDI202319295 A EC DI202319295A EC SP23019295 A ECSP23019295 A EC SP23019295A
Authority
EC
Ecuador
Prior art keywords
compositions
expec
methods
multivalent vaccines
coli
Prior art date
Application number
ECSENADI202319295A
Other languages
English (en)
Spanish (es)
Inventor
Kellen Fae
Michal Sarnecki
Bart Spiessens
Jeroen Geurtsen
Frank Struyf
Jan Poolman
Darren Abbanat
Original Assignee
Janssen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceuticals Inc filed Critical Janssen Pharmaceuticals Inc
Publication of ECSP23019295A publication Critical patent/ECSP23019295A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739Lipopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0258Escherichia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6415Toxins or lectins, e.g. clostridial toxins or Pseudomonas exotoxins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55583Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/62Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
ECSENADI202319295A 2020-09-17 2023-03-17 Composiciones de vacunas multivalentes y usos de las mismas ECSP23019295A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063079734P 2020-09-17 2020-09-17
EP21154782 2021-02-02
US202163191471P 2021-05-21 2021-05-21

Publications (1)

Publication Number Publication Date
ECSP23019295A true ECSP23019295A (es) 2023-04-28

Family

ID=77801756

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSENADI202319295A ECSP23019295A (es) 2020-09-17 2023-03-17 Composiciones de vacunas multivalentes y usos de las mismas

Country Status (18)

Country Link
US (2) US12233118B2 (cg-RX-API-DMAC7.html)
EP (1) EP4213870A1 (cg-RX-API-DMAC7.html)
JP (2) JP7481585B2 (cg-RX-API-DMAC7.html)
KR (1) KR20230043157A (cg-RX-API-DMAC7.html)
CN (3) CN119454928A (cg-RX-API-DMAC7.html)
AU (1) AU2021342797B2 (cg-RX-API-DMAC7.html)
BR (1) BR112023004819A2 (cg-RX-API-DMAC7.html)
CA (1) CA3190820C (cg-RX-API-DMAC7.html)
CL (1) CL2023000740A1 (cg-RX-API-DMAC7.html)
CO (1) CO2023002114A2 (cg-RX-API-DMAC7.html)
EC (1) ECSP23019295A (cg-RX-API-DMAC7.html)
IL (2) IL301248B2 (cg-RX-API-DMAC7.html)
MX (1) MX2023003169A (cg-RX-API-DMAC7.html)
PE (1) PE20231385A1 (cg-RX-API-DMAC7.html)
PH (1) PH12023550020A1 (cg-RX-API-DMAC7.html)
TW (1) TW202227128A (cg-RX-API-DMAC7.html)
UY (1) UY39428A (cg-RX-API-DMAC7.html)
WO (1) WO2022058945A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

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IL286467B1 (en) 2019-03-18 2025-10-01 Janssen Pharmaceuticals Inc Methods for producing bioconjugates of E. COLI O-antigen polysaccharides, preparations thereof and methods for using them
UY38616A (es) 2019-03-18 2020-09-30 Janssen Pharmaceuticals Inc Bioconjugados de polisacáridos del antígeno-o de e. coli y métodos de producción y de uso de los mismos.
AR131046A1 (es) * 2022-11-15 2025-02-12 Janssen Pharmaceuticals Inc Composiciones de vacunas multivalentes y sus usos
WO2024146325A1 (zh) * 2023-01-06 2024-07-11 中国人民解放军军事科学院军事医学研究院 用于生产抗原多糖-载体蛋白生物偶联产物的工程菌及其应用
GB202302579D0 (en) * 2023-02-23 2023-04-12 Glaxosmithkline Biologicals Sa Immunogenic composition
WO2024186262A1 (en) * 2023-03-03 2024-09-12 Agency For Science, Technology And Research Use of o-antigens for treating bacterial infections
EP4478050A1 (en) 2023-06-12 2024-12-18 Janssen Pharmaceuticals, Inc. Method for quantifying bound acetate in glycoconjugates

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UY38616A (es) 2019-03-18 2020-09-30 Janssen Pharmaceuticals Inc Bioconjugados de polisacáridos del antígeno-o de e. coli y métodos de producción y de uso de los mismos.
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Also Published As

Publication number Publication date
KR20230043157A (ko) 2023-03-30
WO2022058945A1 (en) 2022-03-24
IL308201A (en) 2024-01-01
CL2023000740A1 (es) 2023-09-29
CA3190820A1 (en) 2022-03-24
CN115803087A (zh) 2023-03-14
BR112023004819A2 (pt) 2023-04-18
CN119454928A (zh) 2025-02-18
AU2021342797B2 (en) 2024-02-08
JP7481585B2 (ja) 2024-05-10
MX2023003169A (es) 2023-03-27
PH12023550020A1 (en) 2024-03-11
IL301248B2 (en) 2024-04-01
US20220088165A1 (en) 2022-03-24
CO2023002114A2 (es) 2023-03-07
JP2023539943A (ja) 2023-09-20
US20250222088A1 (en) 2025-07-10
PE20231385A1 (es) 2023-09-12
UY39428A (es) 2022-03-31
TW202227128A (zh) 2022-07-16
AU2021342797A1 (en) 2023-02-16
CA3190820C (en) 2024-11-19
EP4213870A1 (en) 2023-07-26
US12233118B2 (en) 2025-02-25
IL301248A (en) 2023-05-01
CN119454927A (zh) 2025-02-18
IL301248B1 (en) 2023-12-01
JP2024099716A (ja) 2024-07-25
CN115803087B (zh) 2024-12-06

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