ECSP088501A - FORMA CRISTALINA DE 1´-(1-METILETIL)-4´-[(2-FLUORO-4-METOXIFENIL)METIL]-5´-METIL-1H-PIRAZOL-3´-O-ß-D-GLUCOPIRANÓSIDO, UN MÉTODO PARA SU PREPARACIÓN Y EL USO DE LA MISMA PARA PREPARAR MEDICAMENTOS - Google Patents

FORMA CRISTALINA DE 1´-(1-METILETIL)-4´-[(2-FLUORO-4-METOXIFENIL)METIL]-5´-METIL-1H-PIRAZOL-3´-O-ß-D-GLUCOPIRANÓSIDO, UN MÉTODO PARA SU PREPARACIÓN Y EL USO DE LA MISMA PARA PREPARAR MEDICAMENTOS

Info

Publication number
ECSP088501A
ECSP088501A EC2008008501A ECSP088501A ECSP088501A EC SP088501 A ECSP088501 A EC SP088501A EC 2008008501 A EC2008008501 A EC 2008008501A EC SP088501 A ECSP088501 A EC SP088501A EC SP088501 A ECSP088501 A EC SP088501A
Authority
EC
Ecuador
Prior art keywords
methyl
same
fluoro
preparation
methytile
Prior art date
Application number
EC2008008501A
Other languages
English (en)
Inventor
Peter Eickelmann
Leo Thomas
Gerd F Kraemer
Adil Duran
Hans-Juergen Martin
Klaus Dugi
Sabine Pinnetti
Regine Ritter
Ruediger Streicher
Gebhard Adelgoss
Gebhard Schilcher
Steffen Maier
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of ECSP088501A publication Critical patent/ECSP088501A/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

La invención se refiere a una forma cristalina de 1´-(1-metiletil)-4´-[(2-fluoro-4-metoxifenil)metil]-5´-metil-1H-pirazol-3´-O-b-D-glucopiranósido, a un método para la preparación de la misma, así como al uso de la misma para preparar medicamentos.
EC2008008501A 2006-01-11 2008-06-04 FORMA CRISTALINA DE 1´-(1-METILETIL)-4´-[(2-FLUORO-4-METOXIFENIL)METIL]-5´-METIL-1H-PIRAZOL-3´-O-ß-D-GLUCOPIRANÓSIDO, UN MÉTODO PARA SU PREPARACIÓN Y EL USO DE LA MISMA PARA PREPARAR MEDICAMENTOS ECSP088501A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06000483 2006-01-11

Publications (1)

Publication Number Publication Date
ECSP088501A true ECSP088501A (es) 2008-07-30

Family

ID=35953998

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2008008501A ECSP088501A (es) 2006-01-11 2008-06-04 FORMA CRISTALINA DE 1´-(1-METILETIL)-4´-[(2-FLUORO-4-METOXIFENIL)METIL]-5´-METIL-1H-PIRAZOL-3´-O-ß-D-GLUCOPIRANÓSIDO, UN MÉTODO PARA SU PREPARACIÓN Y EL USO DE LA MISMA PARA PREPARAR MEDICAMENTOS

Country Status (19)

Country Link
US (2) US7524822B2 (es)
EP (1) EP1976859A1 (es)
JP (1) JP4936234B2 (es)
KR (1) KR20090012205A (es)
CN (1) CN101370816A (es)
AR (1) AR058962A1 (es)
AU (1) AU2007204368A1 (es)
BR (1) BRPI0706375A2 (es)
CA (1) CA2635203A1 (es)
EA (1) EA200801663A1 (es)
EC (1) ECSP088501A (es)
IL (1) IL192655A0 (es)
NO (1) NO20082395L (es)
NZ (1) NZ570311A (es)
PE (1) PE20071237A1 (es)
TW (1) TW200745149A (es)
UY (1) UY30082A1 (es)
WO (1) WO2007080170A1 (es)
ZA (1) ZA200804151B (es)

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JP5467040B2 (ja) * 2008-04-16 2014-04-09 キッセイ薬品工業株式会社 ピラゾール誘導体の1/2フマル酸塩
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WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
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WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
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WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
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WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2014161836A1 (en) 2013-04-04 2014-10-09 Boehringer Ingelheim Vetmedica Gmbh Treatment of metabolic disorders in equine animals
PL3082829T3 (pl) 2013-12-17 2021-09-06 Boehringer Ingelheim Vetmedica Gmbh Inhibitory sglt2 do leczenia zaburzeń metabolicznych u zwierząt kotowatych
US10603300B2 (en) * 2014-01-23 2020-03-31 Boehringer Ingelheim Vetmedica Gmbh Treatment of metabolic disorders in canine animals
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Also Published As

Publication number Publication date
US20090181905A1 (en) 2009-07-16
PE20071237A1 (es) 2008-01-15
TW200745149A (en) 2007-12-16
CA2635203A1 (en) 2007-07-19
NZ570311A (en) 2010-05-28
IL192655A0 (en) 2009-02-11
US7838500B2 (en) 2010-11-23
AR058962A1 (es) 2008-03-05
CN101370816A (zh) 2009-02-18
EA200801663A1 (ru) 2009-02-27
KR20090012205A (ko) 2009-02-02
AU2007204368A1 (en) 2007-07-19
JP4936234B2 (ja) 2012-05-23
ZA200804151B (en) 2009-10-28
JP2009522340A (ja) 2009-06-11
EP1976859A1 (en) 2008-10-08
BRPI0706375A2 (pt) 2011-03-22
WO2007080170A1 (en) 2007-07-19
US20070244176A1 (en) 2007-10-18
UY30082A1 (es) 2007-08-31
US7524822B2 (en) 2009-04-28
NO20082395L (no) 2008-07-31

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