DK2084130T3 - Fremgangsmåde til fremstilling af 5-alkyl-7H-pyrrolo[2,3-d]pyrimidin-2-oler - Google Patents

Fremgangsmåde til fremstilling af 5-alkyl-7H-pyrrolo[2,3-d]pyrimidin-2-oler

Info

Publication number
DK2084130T3
DK2084130T3 DK07844489.0T DK07844489T DK2084130T3 DK 2084130 T3 DK2084130 T3 DK 2084130T3 DK 07844489 T DK07844489 T DK 07844489T DK 2084130 T3 DK2084130 T3 DK 2084130T3
Authority
DK
Denmark
Prior art keywords
ols
pyrrolo
pyrimidin
alkyl
preparation
Prior art date
Application number
DK07844489.0T
Other languages
English (en)
Inventor
Mark S Bednarz
Ramanaiah C Kanamarlapudi
Wenxue Wu
Original Assignee
Lexicon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lexicon Pharmaceuticals Inc filed Critical Lexicon Pharmaceuticals Inc
Application granted granted Critical
Publication of DK2084130T3 publication Critical patent/DK2084130T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK07844489.0T 2006-10-23 2007-10-22 Fremgangsmåde til fremstilling af 5-alkyl-7H-pyrrolo[2,3-d]pyrimidin-2-oler DK2084130T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85389106P 2006-10-23 2006-10-23
PCT/US2007/082049 WO2008051887A1 (en) 2006-10-23 2007-10-22 Process for preparing 5-alkyl-7h-pyrrolo[2,3-d]pyrimidine-2-ols

Publications (1)

Publication Number Publication Date
DK2084130T3 true DK2084130T3 (da) 2012-09-17

Family

ID=38962766

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07844489.0T DK2084130T3 (da) 2006-10-23 2007-10-22 Fremgangsmåde til fremstilling af 5-alkyl-7H-pyrrolo[2,3-d]pyrimidin-2-oler

Country Status (19)

Country Link
US (1) US7951941B2 (da)
EP (1) EP2084130B1 (da)
JP (1) JP5253403B2 (da)
KR (1) KR20090091140A (da)
CN (1) CN101535251B (da)
AU (1) AU2007309131B2 (da)
BR (1) BRPI0717473A2 (da)
CA (1) CA2667267A1 (da)
DK (1) DK2084130T3 (da)
EA (1) EA016132B1 (da)
ES (1) ES2390366T3 (da)
HK (1) HK1132730A1 (da)
IL (1) IL198203A0 (da)
MX (1) MX2009004371A (da)
NZ (1) NZ576291A (da)
PL (1) PL2084130T3 (da)
PT (1) PT2084130E (da)
WO (1) WO2008051887A1 (da)
ZA (1) ZA200902715B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010011450A (es) 2008-04-21 2010-11-10 Lexicon Pharmaceuticals Inc Inhibidores del limk2, composiciones que los comprenden y metodos para su uso.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753664A (en) 1995-03-16 1998-05-19 Takeda Chemical Industries, Ltd. Heterocyclic compounds, their production and use
FR2881742B1 (fr) * 2005-02-10 2007-09-07 Aventis Pharma Sa Pyrroles substitues, compositions les contenant, procede de fabrication et utilisation

Also Published As

Publication number Publication date
AU2007309131B2 (en) 2012-06-21
NZ576291A (en) 2011-10-28
WO2008051887A1 (en) 2008-05-02
AU2007309131A1 (en) 2008-05-02
PT2084130E (pt) 2012-08-22
MX2009004371A (es) 2009-06-11
CN101535251B (zh) 2012-08-22
HK1132730A1 (da) 2010-03-05
CA2667267A1 (en) 2008-05-02
KR20090091140A (ko) 2009-08-26
BRPI0717473A2 (pt) 2014-03-11
JP5253403B2 (ja) 2013-07-31
EA016132B1 (ru) 2012-02-28
CN101535251A (zh) 2009-09-16
EA200970406A1 (ru) 2009-10-30
US7951941B2 (en) 2011-05-31
ES2390366T3 (es) 2012-11-12
EP2084130A1 (en) 2009-08-05
US20080097098A1 (en) 2008-04-24
JP2010507591A (ja) 2010-03-11
IL198203A0 (en) 2009-12-24
ZA200902715B (en) 2010-07-28
PL2084130T3 (pl) 2012-11-30
EP2084130B1 (en) 2012-06-27

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