EA200801663A1 - КРИСТАЛЛИЧЕСКАЯ ФОРМА 1'-(1-МЕТИЛЭТИЛ)-4'-[(2-ФТОР-4-МЕТОКСИФЕНИЛ)МЕТИЛ]-5'-МЕТИЛ-1H-ПИРАЗОЛ-3'-O-β-D-ГЛЮКОПИРАНОЗИДА, СПОСОБ ЕГО ПОЛУЧЕНИЯ И ЕГО ПРИМЕНЕНИЕ ДЛЯ ПРИГОТОВЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ - Google Patents

КРИСТАЛЛИЧЕСКАЯ ФОРМА 1'-(1-МЕТИЛЭТИЛ)-4'-[(2-ФТОР-4-МЕТОКСИФЕНИЛ)МЕТИЛ]-5'-МЕТИЛ-1H-ПИРАЗОЛ-3'-O-β-D-ГЛЮКОПИРАНОЗИДА, СПОСОБ ЕГО ПОЛУЧЕНИЯ И ЕГО ПРИМЕНЕНИЕ ДЛЯ ПРИГОТОВЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ

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Publication number
EA200801663A1
EA200801663A1 EA200801663A EA200801663A EA200801663A1 EA 200801663 A1 EA200801663 A1 EA 200801663A1 EA 200801663 A EA200801663 A EA 200801663A EA 200801663 A EA200801663 A EA 200801663A EA 200801663 A1 EA200801663 A1 EA 200801663A1
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EA
Eurasian Patent Office
Prior art keywords
methyl
preparation
methylethyl
medicines
fluoro
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EA200801663A
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English (en)
Inventor
Герд Крэмер
Ханс-Юрген Мартин
Гебхард Адельгосс
Клаус Дуги
Адиль Дуран
Петер Айкельманн
Штефен Майер
Забине Пинетти
Регине Риттер
Гебхард Шильшер
Рюдигер Штрайхер
Лео Томас
Original Assignee
Бёрингер Ингельхайм Интернациональ Гмбх
Аджиномото Ко., Лтд.
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Publication of EA200801663A1 publication Critical patent/EA200801663A1/ru

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

В заявке описана кристаллическая форма 1'-(1-метилэтил)-4'-[(2-фтор-4-метоксифенил)метил]-5'-метил-1Н-пиразол-3'-O-β-O-глюкопиранозида, способ его получения, а также его применение для приготовления лекарственных средств.
EA200801663A 2006-01-11 2007-01-10 КРИСТАЛЛИЧЕСКАЯ ФОРМА 1'-(1-МЕТИЛЭТИЛ)-4'-[(2-ФТОР-4-МЕТОКСИФЕНИЛ)МЕТИЛ]-5'-МЕТИЛ-1H-ПИРАЗОЛ-3'-O-β-D-ГЛЮКОПИРАНОЗИДА, СПОСОБ ЕГО ПОЛУЧЕНИЯ И ЕГО ПРИМЕНЕНИЕ ДЛЯ ПРИГОТОВЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ EA200801663A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06000483 2006-01-11
PCT/EP2007/050209 WO2007080170A1 (en) 2006-01-11 2007-01-10 CRYSTALLINE FORM OF 1´-(1-METHYLETHYL)- 4´-[(2-FLUORO-4-METHOXYPHENYL)METHYL]-5´-METHYL-1H-PYRAZOL-3´-O-β-D-GLUCOPYRANOSIDE, A METHOD FOR ITS PREPARATION AND THE USE THEREOF FOR PREPARING MEDICAMENTS

Publications (1)

Publication Number Publication Date
EA200801663A1 true EA200801663A1 (ru) 2009-02-27

Family

ID=35953998

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200801663A EA200801663A1 (ru) 2006-01-11 2007-01-10 КРИСТАЛЛИЧЕСКАЯ ФОРМА 1'-(1-МЕТИЛЭТИЛ)-4'-[(2-ФТОР-4-МЕТОКСИФЕНИЛ)МЕТИЛ]-5'-МЕТИЛ-1H-ПИРАЗОЛ-3'-O-β-D-ГЛЮКОПИРАНОЗИДА, СПОСОБ ЕГО ПОЛУЧЕНИЯ И ЕГО ПРИМЕНЕНИЕ ДЛЯ ПРИГОТОВЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ

Country Status (19)

Country Link
US (2) US7524822B2 (ru)
EP (1) EP1976859A1 (ru)
JP (1) JP4936234B2 (ru)
KR (1) KR20090012205A (ru)
CN (1) CN101370816A (ru)
AR (1) AR058962A1 (ru)
AU (1) AU2007204368A1 (ru)
BR (1) BRPI0706375A2 (ru)
CA (1) CA2635203A1 (ru)
EA (1) EA200801663A1 (ru)
EC (1) ECSP088501A (ru)
IL (1) IL192655A0 (ru)
NO (1) NO20082395L (ru)
NZ (1) NZ570311A (ru)
PE (1) PE20071237A1 (ru)
TW (1) TW200745149A (ru)
UY (1) UY30082A1 (ru)
WO (1) WO2007080170A1 (ru)
ZA (1) ZA200804151B (ru)

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EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
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Also Published As

Publication number Publication date
ZA200804151B (en) 2009-10-28
JP4936234B2 (ja) 2012-05-23
JP2009522340A (ja) 2009-06-11
AU2007204368A1 (en) 2007-07-19
PE20071237A1 (es) 2008-01-15
EP1976859A1 (en) 2008-10-08
AR058962A1 (es) 2008-03-05
US20090181905A1 (en) 2009-07-16
KR20090012205A (ko) 2009-02-02
BRPI0706375A2 (pt) 2011-03-22
CA2635203A1 (en) 2007-07-19
TW200745149A (en) 2007-12-16
US20070244176A1 (en) 2007-10-18
CN101370816A (zh) 2009-02-18
NZ570311A (en) 2010-05-28
ECSP088501A (es) 2008-07-30
US7838500B2 (en) 2010-11-23
WO2007080170A1 (en) 2007-07-19
NO20082395L (no) 2008-07-31
US7524822B2 (en) 2009-04-28
IL192655A0 (en) 2009-02-11
UY30082A1 (es) 2007-08-31

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