EA200801663A1 - КРИСТАЛЛИЧЕСКАЯ ФОРМА 1'-(1-МЕТИЛЭТИЛ)-4'-[(2-ФТОР-4-МЕТОКСИФЕНИЛ)МЕТИЛ]-5'-МЕТИЛ-1H-ПИРАЗОЛ-3'-O-β-D-ГЛЮКОПИРАНОЗИДА, СПОСОБ ЕГО ПОЛУЧЕНИЯ И ЕГО ПРИМЕНЕНИЕ ДЛЯ ПРИГОТОВЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ - Google Patents

КРИСТАЛЛИЧЕСКАЯ ФОРМА 1'-(1-МЕТИЛЭТИЛ)-4'-[(2-ФТОР-4-МЕТОКСИФЕНИЛ)МЕТИЛ]-5'-МЕТИЛ-1H-ПИРАЗОЛ-3'-O-β-D-ГЛЮКОПИРАНОЗИДА, СПОСОБ ЕГО ПОЛУЧЕНИЯ И ЕГО ПРИМЕНЕНИЕ ДЛЯ ПРИГОТОВЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ

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Publication number
EA200801663A1
EA200801663A1 EA200801663A EA200801663A EA200801663A1 EA 200801663 A1 EA200801663 A1 EA 200801663A1 EA 200801663 A EA200801663 A EA 200801663A EA 200801663 A EA200801663 A EA 200801663A EA 200801663 A1 EA200801663 A1 EA 200801663A1
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EA
Eurasian Patent Office
Prior art keywords
methyl
preparation
methylethyl
medicines
fluoro
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Application number
EA200801663A
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English (en)
Inventor
Герд Крэмер
Ханс-Юрген Мартин
Гебхард Адельгосс
Клаус Дуги
Адиль Дуран
Петер Айкельманн
Штефен Майер
Забине Пинетти
Регине Риттер
Гебхард Шильшер
Рюдигер Штрайхер
Лео Томас
Original Assignee
Бёрингер Ингельхайм Интернациональ Гмбх
Аджиномото Ко., Лтд.
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Application filed by Бёрингер Ингельхайм Интернациональ Гмбх, Аджиномото Ко., Лтд. filed Critical Бёрингер Ингельхайм Интернациональ Гмбх
Publication of EA200801663A1 publication Critical patent/EA200801663A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

В заявке описана кристаллическая форма 1'-(1-метилэтил)-4'-[(2-фтор-4-метоксифенил)метил]-5'-метил-1Н-пиразол-3'-O-β-O-глюкопиранозида, способ его получения, а также его применение для приготовления лекарственных средств.
EA200801663A 2006-01-11 2007-01-10 КРИСТАЛЛИЧЕСКАЯ ФОРМА 1'-(1-МЕТИЛЭТИЛ)-4'-[(2-ФТОР-4-МЕТОКСИФЕНИЛ)МЕТИЛ]-5'-МЕТИЛ-1H-ПИРАЗОЛ-3'-O-β-D-ГЛЮКОПИРАНОЗИДА, СПОСОБ ЕГО ПОЛУЧЕНИЯ И ЕГО ПРИМЕНЕНИЕ ДЛЯ ПРИГОТОВЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ EA200801663A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06000483 2006-01-11
PCT/EP2007/050209 WO2007080170A1 (en) 2006-01-11 2007-01-10 CRYSTALLINE FORM OF 1´-(1-METHYLETHYL)- 4´-[(2-FLUORO-4-METHOXYPHENYL)METHYL]-5´-METHYL-1H-PYRAZOL-3´-O-β-D-GLUCOPYRANOSIDE, A METHOD FOR ITS PREPARATION AND THE USE THEREOF FOR PREPARING MEDICAMENTS

Publications (1)

Publication Number Publication Date
EA200801663A1 true EA200801663A1 (ru) 2009-02-27

Family

ID=35953998

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200801663A EA200801663A1 (ru) 2006-01-11 2007-01-10 КРИСТАЛЛИЧЕСКАЯ ФОРМА 1'-(1-МЕТИЛЭТИЛ)-4'-[(2-ФТОР-4-МЕТОКСИФЕНИЛ)МЕТИЛ]-5'-МЕТИЛ-1H-ПИРАЗОЛ-3'-O-β-D-ГЛЮКОПИРАНОЗИДА, СПОСОБ ЕГО ПОЛУЧЕНИЯ И ЕГО ПРИМЕНЕНИЕ ДЛЯ ПРИГОТОВЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ

Country Status (19)

Country Link
US (2) US7524822B2 (ru)
EP (1) EP1976859A1 (ru)
JP (1) JP4936234B2 (ru)
KR (1) KR20090012205A (ru)
CN (1) CN101370816A (ru)
AR (1) AR058962A1 (ru)
AU (1) AU2007204368A1 (ru)
BR (1) BRPI0706375A2 (ru)
CA (1) CA2635203A1 (ru)
EA (1) EA200801663A1 (ru)
EC (1) ECSP088501A (ru)
IL (1) IL192655A0 (ru)
NO (1) NO20082395L (ru)
NZ (1) NZ570311A (ru)
PE (1) PE20071237A1 (ru)
TW (1) TW200745149A (ru)
UY (1) UY30082A1 (ru)
WO (1) WO2007080170A1 (ru)
ZA (1) ZA200804151B (ru)

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US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
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EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
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DK3082829T3 (da) 2013-12-17 2021-05-03 Boehringer Ingelheim Vetmedica Gmbh Sglt2-inhibitorer til behandlingen af metaboliske lidelser i kattedyr
LT3485890T (lt) * 2014-01-23 2023-07-25 Boehringer Ingelheim Vetmedica Gmbh Sglt2 inhibitoriai, skirti šuninių gyvūnų medžiagų apykaitos sutrikimų gydymui
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Also Published As

Publication number Publication date
ZA200804151B (en) 2009-10-28
JP4936234B2 (ja) 2012-05-23
JP2009522340A (ja) 2009-06-11
AU2007204368A1 (en) 2007-07-19
PE20071237A1 (es) 2008-01-15
EP1976859A1 (en) 2008-10-08
AR058962A1 (es) 2008-03-05
US20090181905A1 (en) 2009-07-16
KR20090012205A (ko) 2009-02-02
BRPI0706375A2 (pt) 2011-03-22
CA2635203A1 (en) 2007-07-19
TW200745149A (en) 2007-12-16
US20070244176A1 (en) 2007-10-18
CN101370816A (zh) 2009-02-18
NZ570311A (en) 2010-05-28
ECSP088501A (es) 2008-07-30
US7838500B2 (en) 2010-11-23
WO2007080170A1 (en) 2007-07-19
NO20082395L (no) 2008-07-31
US7524822B2 (en) 2009-04-28
IL192655A0 (en) 2009-02-11
UY30082A1 (es) 2007-08-31

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