ECSP077898A - Métodos y composiciones para modular la adhesión y la tolerancia al estrés en bacterias - Google Patents

Métodos y composiciones para modular la adhesión y la tolerancia al estrés en bacterias

Info

Publication number
ECSP077898A
ECSP077898A EC2007007898A ECSP077898A ECSP077898A EC SP077898 A ECSP077898 A EC SP077898A EC 2007007898 A EC2007007898 A EC 2007007898A EC SP077898 A ECSP077898 A EC SP077898A EC SP077898 A ECSP077898 A EC SP077898A
Authority
EC
Ecuador
Prior art keywords
bacteria
adhesion
methods
stress tolerance
compositions
Prior art date
Application number
EC2007007898A
Other languages
English (en)
Inventor
B Logan Buck
Andrea Azcarate-Peril
Todd R Klaenhammer
Eric Altermann
Original Assignee
North Carolina State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by North Carolina State University filed Critical North Carolina State University
Publication of ECSP077898A publication Critical patent/ECSP077898A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus
    • C12R2001/23—Lactobacillus acidophilus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Métodos y composiciones que mejoran la adhesión de una bacteria a sustratos blanco y/o mejoran la tolerancia al estrés de una bacteria. Los métodos comprenden exponer al bacteria a condiciones para adaptar la adhesión, y con ello incrementar la actividad de adhesión y/o la tolerancia al estrés de la bacteria. Además, se proporcionan bacterias que tienen una producción modulada de autoinductor-2. Las composiciones incluyen bacterias recombinantes que expresan moléculas de ácidos nucleicos que participan en la vía de producción del autoinductor-2. Además, se proporcionan proteínas de fusión relacionadas con el autoinductor-2, péptidos antigénicos, anticuerpos y vectores. Además, se proporcionan métodos para analizar compuestos o condiciones ambientales que estimulen la producción del autoinductor-2 y/o produzcan una respuesta adaptativa de al adhesión, al igual que diversos métodos para usar las bacterias que tienen una adhesión y/o una tolerancia al estrés incrementada.
EC2007007898A 2005-04-15 2007-11-14 Métodos y composiciones para modular la adhesión y la tolerancia al estrés en bacterias ECSP077898A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67188705P 2005-04-15 2005-04-15

Publications (1)

Publication Number Publication Date
ECSP077898A true ECSP077898A (es) 2008-01-23

Family

ID=37028280

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2007007898A ECSP077898A (es) 2005-04-15 2007-11-14 Métodos y composiciones para modular la adhesión y la tolerancia al estrés en bacterias

Country Status (11)

Country Link
US (1) US20060269998A1 (es)
EP (3) EP2302032A1 (es)
JP (1) JP2008537885A (es)
CN (2) CN102212543A (es)
AU (1) AU2006236629B2 (es)
BR (1) BRPI0610609A2 (es)
CA (1) CA2605162A1 (es)
EC (1) ECSP077898A (es)
MX (1) MX2007012755A (es)
NZ (1) NZ563246A (es)
WO (1) WO2006113475A2 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003298770A1 (en) * 2002-12-02 2004-06-23 Biosynexus Inc Wall teichoic acid as a target for anti-staphylococcal therapies and vaccines
WO2010075424A2 (en) * 2008-12-22 2010-07-01 The Regents Of University Of California Compositions and methods for downregulating prokaryotic genes
JP5612269B2 (ja) * 2009-04-24 2014-10-22 花王株式会社 歯周病マーカー
US8445226B2 (en) 2010-02-01 2013-05-21 Microbios, Inc. Process and composition for the manufacture of a microbial-based product
US7888062B1 (en) 2010-02-01 2011-02-15 Microbios, Inc. Process and composition for the manufacture of a microbial-based product
CN103275920B (zh) * 2013-05-16 2015-04-15 江南大学 一种提高乳酸菌粘附肠道上皮细胞能力的方法
WO2018089924A2 (en) * 2016-11-11 2018-05-17 The Trustees Of Columbia University In The City Of New York Systems and methods for fabricating water-responsive actuators
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
CN110684685B (zh) * 2019-10-14 2021-03-30 广西大学 发酵乳杆菌Lactobacillus fermentum 9-4及其应用
CN110669690B (zh) * 2019-10-16 2021-04-06 衡阳师范学院 一种表达群体感应信号分子ai-2的植物乳杆菌菌株及其应用
CN111304121A (zh) * 2020-02-24 2020-06-19 中国水产科学研究院黄海水产研究所 一株致病性海洋哈氏弧菌及其应用
CN111518741B (zh) * 2020-04-27 2022-11-08 微康益生菌(苏州)股份有限公司 一种提高乳酸菌口腔粘附能力的方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336336A (en) 1979-01-12 1982-06-22 President And Fellows Of Harvard College Fused gene and method of making and using same
ZA811368B (en) 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
US4551433A (en) 1981-05-18 1985-11-05 Genentech, Inc. Microbial hybrid promoters
NZ201918A (en) 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
JPS59166086A (ja) 1983-03-09 1984-09-19 Teruhiko Beppu 新規な発現型プラスミドとそれらを用いて仔牛プロキモシン遺伝子を大腸菌内で発現させる方法
US4689406A (en) 1983-08-10 1987-08-25 Amgen Enhancement of microbial expression of polypeptides
US4738921A (en) 1984-09-27 1988-04-19 Eli Lilly And Company Derivative of the tryptophan operon for expression of fused gene products
SE463598B (sv) * 1984-11-08 1990-12-17 Chemical Dynamics Sweden Ab Preparat, avsett att oeka vidhaeftningen av bakterier till mag-tarmkanalen hos maenniskor och djur, samt ett framstaellningsfoerfarande foer detta
US5028530A (en) 1985-01-28 1991-07-02 Xoma Corporation AraB promoters and method of producing polypeptides, including cecropins, by microbiological techniques
JPS63123383A (ja) 1986-11-11 1988-05-27 Mitsubishi Kasei Corp ハイブリツドプロモ−タ−、発現調節ｄｎａ配列および発現ベクタ−
US5412087A (en) 1992-04-24 1995-05-02 Affymax Technologies N.V. Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces
US5532142A (en) 1993-02-12 1996-07-02 Board Of Regents, The University Of Texas System Method of isolation and purification of fusion polypeptides
US5861242A (en) 1993-06-25 1999-01-19 Affymetrix, Inc. Array of nucleic acid probes on biological chips for diagnosis of HIV and methods of using the same
WO1995000530A1 (en) 1993-06-25 1995-01-05 Affymax Technologies N.V. Hybridization and sequencing of nucleic acids
US5837832A (en) 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US5545531A (en) 1995-06-07 1996-08-13 Affymax Technologies N.V. Methods for making a device for concurrently processing multiple biological chip assays
GB9521568D0 (en) 1995-10-20 1995-12-20 Lynxvale Ltd Delivery of biologically active polypeptides
FR2753202A1 (fr) * 1996-09-06 1998-03-13 Agronomique Inst Nat Rech Bacteries multiresistantes, procedes d'obtention et utilisation
KR100641969B1 (ko) 1997-07-23 2006-11-06 로셰 디아그노스틱스 게엠베하 내인성 유전자 활성화에 의한 에리트로포이에틴의제조방법
WO2000023471A2 (en) 1998-10-20 2000-04-27 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Use of a cytokine-producing lactococcus strain to treat colitis
US6720415B2 (en) * 1998-12-02 2004-04-13 Princeton University Compositions and methods for regulating bacterial pathogenesis
KR20010101171A (ko) * 1998-12-11 2001-11-14 추후기재 비뇨생식기 감염의 치료 및 예방을 위한 락토바실러스의경구 투여
AU7131600A (en) 1999-06-21 2001-01-09 North Carolina State University Acid-inducible promoters for gene expression
JP4603116B2 (ja) * 1999-12-02 2010-12-22 わかもと製薬株式会社 乳酸菌含有組成物、医薬及び食品
US6569681B1 (en) 2000-03-14 2003-05-27 Transkaryotic Therapies, Inc. Methods of improving homologous recombination
ES2398910T3 (es) * 2001-09-28 2013-03-22 Tntgamble, Inc. Sistema de aporte para componentes biológicos
JP3919635B2 (ja) * 2002-09-05 2007-05-30 明治乳業株式会社 プロバイオティクス乳酸菌のスクリーニング方法
MXPA05010696A (es) * 2003-04-02 2006-04-18 Axcan Pharma S A Cepa de lactobacillus fermentum y usos de la misma.
WO2004096992A2 (en) * 2003-04-25 2004-11-11 North Carolina State University Lactobacillus acidophilus nucleic acid sequences encoding cell surface protein homologues and uses therefore
US20050019379A1 (en) * 2003-07-22 2005-01-27 Kimberly-Clark Worldwide, Inc. Wipe and methods for improving skin health

Also Published As

Publication number Publication date
EP2302032A1 (en) 2011-03-30
US20060269998A1 (en) 2006-11-30
WO2006113475A3 (en) 2007-03-29
CN101198689A (zh) 2008-06-11
EP2305791A1 (en) 2011-04-06
JP2008537885A (ja) 2008-10-02
AU2006236629A1 (en) 2006-10-26
CN102212543A (zh) 2011-10-12
CA2605162A1 (en) 2006-10-26
BRPI0610609A2 (pt) 2010-07-06
MX2007012755A (es) 2008-01-14
WO2006113475A2 (en) 2006-10-26
AU2006236629B2 (en) 2012-04-19
EP1871868A2 (en) 2008-01-02
NZ563246A (en) 2011-09-30

Similar Documents

Publication Publication Date Title
ECSP077898A (es) Métodos y composiciones para modular la adhesión y la tolerancia al estrés en bacterias
GT200900264A (es) Moléculas y métodos para modular la pro-proteina
AR114031A2 (es) Moléculas de unión a 4-1bb
EA201170635A1 (ru) Композиции, способы получения и применение каркаса на основе домена фибронектина типа iii
BR112013007862A2 (pt) ácidos nucleicos manipulados e métodos de uso dos mesmos.
CY1115257T1 (el) ΑΠΟΠΤΩΤΙΚΑ ΑΝΤΙΣΩΜΑΤΑ ΑΝΤΙ-ΙgE ΠΟΥ ΔΕΣΜΕΥΟΝΤΑΙ ΜΕ ΙgE ΔΕΣΜΕΥΜΕΝΗ ΣΕ ΜΕΜΒΡΑΝΗ
EA201270758A1 (ru) Мутанты fgf21 и их применение
EA201171220A1 (ru) Мутанты fgf21 и их применение
NO20082240L (no) GLP-2 imitatorstoff, polypeptider, sammensetninger, fremgangsmater og anvendelser
EA200870619A1 (ru) Модифицированный фермент дикамба-монооксигеназа и способы его применения
MX2009009200A (es) Tratamiento de enfermedades caracterizadas por la inflamacion.
NO20083266L (no) Humane anti-IL-23-antistoffer, sammensetninger, fremgangsmater og anvendelser
MX2014011459A (es) Proteinas nutritivas cargadas y metodos.
BRPI0619579B8 (pt) Métodos para aumentar a expectativa de vida replicativa e/ou estabilidade de uma célula produtora de anticorpo, para expressar um gene de uma célula b codificando a cadeia pesada de ig e/ou cadeia leve de ig, para produzir linhagem de células b, para obter anticorpos, e, método ex vivo para produzir anticorpos capazes de especificamente ligar um antígeno de interesse
AR061294A1 (es) Plantas con caracteristicas de crecimiento mejoradas y metodo para prepararlas
AR069115A1 (es) Composiciones y metodos para modular caracteristicas de las plantas, tal como tolerancia al estres
AR076941A1 (es) Cepa de bacillus para una mayor produccion de proteina
AR079707A1 (es) Celula aislada de ovario de hamster chino util para la produccion de anticuerpos terapeuticos
ATE512228T1 (de) Induzierbare expressionssysteme
AR067672A1 (es) Plantas que tienen rasgos mejorados relacionados con el rendimiento y un metodo para obtenerlas
BRPI0514572A (pt) ácidos de tiazolo-naftila
EP4249064A3 (en) Novel fusion protein specific for cd137 and pd-l1
AR113492A2 (es) Furina recombinante libre de proteínas sustancialmente animal y métodos para producirla
EA201892503A1 (ru) Модуляция метаболизма липидов для продуцирования белков
AR071232A1 (es) Proteina hibrida usada como vacuna contra toxinas shiga de e. coli