EA201690069A1 - Применение высоких доз придопидина для лечения болезни хантингтона - Google Patents

Применение высоких доз придопидина для лечения болезни хантингтона

Info

Publication number
EA201690069A1
EA201690069A1 EA201690069A EA201690069A EA201690069A1 EA 201690069 A1 EA201690069 A1 EA 201690069A1 EA 201690069 A EA201690069 A EA 201690069A EA 201690069 A EA201690069 A EA 201690069A EA 201690069 A1 EA201690069 A1 EA 201690069A1
Authority
EA
Eurasian Patent Office
Prior art keywords
disease
hantington
treatment
high dose
patient
Prior art date
Application number
EA201690069A
Other languages
English (en)
Russian (ru)
Inventor
Мерав Бассан
Эли Эял
Эстер Люкасевич Хагай
Анна Кристина Свеинсдоттер Теиге Виккенберг
Original Assignee
Тева Фармасьютикалз Интернэшнл Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52105289&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201690069(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Тева Фармасьютикалз Интернэшнл Гмбх filed Critical Тева Фармасьютикалз Интернэшнл Гмбх
Publication of EA201690069A1 publication Critical patent/EA201690069A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EA201690069A 2013-06-21 2014-06-19 Применение высоких доз придопидина для лечения болезни хантингтона EA201690069A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361837928P 2013-06-21 2013-06-21
US201361877832P 2013-09-13 2013-09-13
PCT/US2014/043204 WO2014205229A1 (en) 2013-06-21 2014-06-19 Use of high dose pridopidine for treating huntington's disease

Publications (1)

Publication Number Publication Date
EA201690069A1 true EA201690069A1 (ru) 2016-06-30

Family

ID=52105289

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201690069A EA201690069A1 (ru) 2013-06-21 2014-06-19 Применение высоких доз придопидина для лечения болезни хантингтона

Country Status (24)

Country Link
US (1) US10322119B2 (cg-RX-API-DMAC10.html)
EP (1) EP3010506B1 (cg-RX-API-DMAC10.html)
JP (1) JP2016523862A (cg-RX-API-DMAC10.html)
KR (1) KR102316933B1 (cg-RX-API-DMAC10.html)
CN (1) CN105592848A (cg-RX-API-DMAC10.html)
AU (1) AU2014281414A1 (cg-RX-API-DMAC10.html)
BR (1) BR112015029918A2 (cg-RX-API-DMAC10.html)
CA (1) CA2913781C (cg-RX-API-DMAC10.html)
CL (1) CL2015003690A1 (cg-RX-API-DMAC10.html)
DK (1) DK3010506T3 (cg-RX-API-DMAC10.html)
EA (1) EA201690069A1 (cg-RX-API-DMAC10.html)
ES (1) ES2879631T3 (cg-RX-API-DMAC10.html)
HK (1) HK1221646A1 (cg-RX-API-DMAC10.html)
HU (1) HUE054783T2 (cg-RX-API-DMAC10.html)
IL (1) IL242804B (cg-RX-API-DMAC10.html)
MX (1) MX384234B (cg-RX-API-DMAC10.html)
PE (2) PE20170302A1 (cg-RX-API-DMAC10.html)
PH (1) PH12015502691A1 (cg-RX-API-DMAC10.html)
PL (1) PL3010506T3 (cg-RX-API-DMAC10.html)
SG (1) SG11201509729YA (cg-RX-API-DMAC10.html)
TW (1) TW201529069A (cg-RX-API-DMAC10.html)
UA (1) UA122999C2 (cg-RX-API-DMAC10.html)
UY (1) UY35624A (cg-RX-API-DMAC10.html)
WO (1) WO2014205229A1 (cg-RX-API-DMAC10.html)

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US11090297B2 (en) 2013-06-21 2021-08-17 Prilenia Neurotherapeutics Ltd. Pridopidine for treating huntington's disease
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TW201613859A (en) 2014-06-30 2016-04-16 Teva Pharma Analogs of PRIDOPIDINE, their preparation and use
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US11471449B2 (en) 2015-02-25 2022-10-18 Prilenia Neurotherapeutics Ltd. Use of pridopidine to improve cognitive function and for treating Alzheimer's disease
EP3854785A1 (en) 2015-02-25 2021-07-28 Prilenia Neurotherapeutics Ltd. Use of pridopidine to treat depression or anxiety
EP3324967A4 (en) * 2015-07-22 2019-03-20 Prilenia Therapeutics Development Ltd. PRIDOPIDINE-BASED FORMULATIONS AND USE OF THE SAME
AR105434A1 (es) 2015-07-22 2017-10-04 Teva Pharmaceuticals Int Gmbh Proceso para preparar pridopidina
EP3419622B1 (en) 2016-02-24 2024-03-06 Prilenia Neurotherapeutics Ltd. Treatment of neurodegenerative eye disease using pridopidine
IL311081A (en) 2016-08-24 2024-04-01 Prilenia Neurotherapeutics Ltd Use of pyridofidine to treat functional decline
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AU2017326436A1 (en) * 2016-09-15 2019-04-11 Prilenia Neurotherapeutics Ltd Use of pridopidine for the treatment of anxiety and depression
US12102627B2 (en) 2016-09-16 2024-10-01 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating rett syndrome
ES2909557T3 (es) 2016-09-16 2022-05-09 Prilenia Neurotherapeutics Ltd Utilización de la pridopidina para el tratamiento del síndrome de Rett
ES2972205T3 (es) 2017-01-20 2024-06-11 Prilenia Neurotherapeutics Ltd Pridopidina para el tratamiento del síndrome x frágil
US20260091028A1 (en) * 2017-08-14 2026-04-02 Prilenia Neurotherapeutics Ltd. Method of treating amyotrophic lateral sclerosis with pridopidine
HUE061505T2 (hu) * 2017-08-14 2023-07-28 Prilenia Neurotherapeutics Ltd Módszer amyothrophiás lateralsclerosis kezelésére pridopidinnel
JP2020532517A (ja) * 2017-08-30 2020-11-12 プリレニア ニューロセラピューティクス リミテッド 高濃度プリドピジン製剤
CA3075020C (en) 2017-09-08 2021-12-07 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
US12036213B2 (en) 2017-09-08 2024-07-16 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
EP3917380B1 (en) * 2019-01-31 2025-03-19 F. Hoffmann-La Roche AG Assessing progression of huntington's disease
JP7585561B2 (ja) 2019-02-04 2024-11-19 プリレニア ニューロセラピューティクス リミテッド パーキンソン病およびパーキンソニズムに関連する他の疾患のための低用量プリドピジン
AU2020243692B2 (en) 2019-03-15 2023-03-02 Prilenia Neurotherapeutics Ltd. Treatment of mitochondrial associated diseases and disorders, including symptoms thereof using pridopidine
SMT202600016T1 (it) * 2019-06-12 2026-03-09 Prilenia Neurotherapeutics Ltd Composizione contenente pridopidina e un suo analogo per il trattamento della malattia di huntington e dei suoi sintomi
CN114727761A (zh) * 2019-09-17 2022-07-08 豪夫迈·罗氏有限公司 患有运动障碍的患者的个性化保健的改善
CN116472043A (zh) 2020-10-20 2023-07-21 普瑞尼亚神经治疗有限公司 普利多匹定和类似物用于治疗焦虑和抑郁的用途
WO2022094565A1 (en) * 2020-10-28 2022-05-05 Buck Institute For Research On Aging N-propargylglycine: a unique inhibitor of proline dehydrogenase with brain-enhancing mitohormesis properties capable of mitigating neurodegenerative disorders
CA3214354A1 (en) * 2021-04-14 2022-10-20 Michael Hayden Treatment of prodromal huntington disease
WO2025181805A1 (en) * 2024-02-27 2025-09-04 Prilenia Neurotherapeutics Ltd. Pridopidine and sigma 2 antagonist agent for treating huntington disease and symptoms thereof

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CA2937243C (en) 2014-01-22 2023-07-18 Teva Pharmaceuticals International Gmbh Modified release formulations of pridopidine
TW201613859A (en) 2014-06-30 2016-04-16 Teva Pharma Analogs of PRIDOPIDINE, their preparation and use
WO2016106142A1 (en) 2014-12-22 2016-06-30 Teva Pharmaceuticals International Gmbh L-tartrate salt of pridopidine
WO2016138135A1 (en) 2015-02-25 2016-09-01 Teva Pharmaceuticals International Gmbh Sigma-1 receptor modulators for treating huntington's disease
EP3854785A1 (en) 2015-02-25 2021-07-28 Prilenia Neurotherapeutics Ltd. Use of pridopidine to treat depression or anxiety
EP3324967A4 (en) 2015-07-22 2019-03-20 Prilenia Therapeutics Development Ltd. PRIDOPIDINE-BASED FORMULATIONS AND USE OF THE SAME
AR105434A1 (es) 2015-07-22 2017-10-04 Teva Pharmaceuticals Int Gmbh Proceso para preparar pridopidina
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IL311081A (en) 2016-08-24 2024-04-01 Prilenia Neurotherapeutics Ltd Use of pyridofidine to treat functional decline
AU2017326436A1 (en) 2016-09-15 2019-04-11 Prilenia Neurotherapeutics Ltd Use of pridopidine for the treatment of anxiety and depression
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Also Published As

Publication number Publication date
MX384234B (es) 2025-03-14
PH12015502691A1 (en) 2016-03-14
KR102316933B1 (ko) 2021-10-26
ES2879631T3 (es) 2021-11-22
CA2913781C (en) 2022-05-10
EP3010506B1 (en) 2021-05-12
HK1221646A1 (zh) 2017-06-09
UY35624A (es) 2015-01-30
JP2016523862A (ja) 2016-08-12
DK3010506T3 (da) 2021-07-12
WO2014205229A1 (en) 2014-12-24
US20140378508A1 (en) 2014-12-25
CL2015003690A1 (es) 2016-10-28
HUE054783T2 (hu) 2021-09-28
UA122999C2 (uk) 2021-02-03
WO2014205229A8 (en) 2015-04-09
IL242804B (en) 2022-02-01
CN105592848A (zh) 2016-05-18
MX2015017307A (es) 2016-08-03
PL3010506T3 (pl) 2021-11-02
CA2913781A1 (en) 2014-12-24
EP3010506A4 (en) 2017-02-08
AU2014281414A1 (en) 2016-01-21
KR20160055122A (ko) 2016-05-17
BR112015029918A2 (pt) 2017-07-25
SG11201509729YA (en) 2015-12-30
US10322119B2 (en) 2019-06-18
PE20170302A1 (es) 2017-03-31
TW201529069A (zh) 2015-08-01
EP3010506A1 (en) 2016-04-27
PE20160195A1 (es) 2016-05-14

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