EA201391382A1 - Способы диагностики и лечения с применением библиотеки лигандов - Google Patents

Способы диагностики и лечения с применением библиотеки лигандов

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EA201391382A1
EA201391382A1 EA201391382A EA201391382A EA201391382A1 EA 201391382 A1 EA201391382 A1 EA 201391382A1 EA 201391382 A EA201391382 A EA 201391382A EA 201391382 A EA201391382 A EA 201391382A EA 201391382 A1 EA201391382 A1 EA 201391382A1
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library
treatment
methods
drug
relates
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EA201391382A
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EA037648B1 (ru
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Муралидхар Редди Моола
Джессика Шилке
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ОПКО ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи
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Publication of EA201391382A1 publication Critical patent/EA201391382A1/ru
Publication of EA037648B1 publication Critical patent/EA037648B1/ru

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Abstract

Настоящее изобретение относится к способам диагностики и лечения с применением библиотеки лигандов. В частности, настоящее изобретение относится к применению библиотеки лигандов для диагностики или детектирования реакции, вызванной лекарственным средством, включая нежелательные реакции на лекарство, побочные эффекты, устойчивость к лекарству и терапевтическую эффективность. Настоящее изобретение также относится к идентификации биомаркеров, ассоциированных с вызванной лекарственным средством реакцией, и обеспечению персонализированного лечения.
EA201391382A 2011-03-24 2012-03-23 Способ диагностики с использованием библиотеки пептоидных лигандов EA037648B1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161467256P 2011-03-24 2011-03-24
US201161491717P 2011-05-31 2011-05-31
US201261583881P 2012-01-06 2012-01-06
PCT/US2012/030223 WO2012129457A2 (en) 2011-03-24 2012-03-23 Diagnostic and treatment methods using a ligand library

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EA201391382A1 true EA201391382A1 (ru) 2014-09-30
EA037648B1 EA037648B1 (ru) 2021-04-27

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EA201391378A EA032582B1 (ru) 2011-03-24 2012-03-22 Библиотека случайных пептоидных лигандов для скрининга биологической жидкости
EA201391382A EA037648B1 (ru) 2011-03-24 2012-03-23 Способ диагностики с использованием библиотеки пептоидных лигандов

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US (2) US9804168B2 (ru)
EP (2) EP2688911B1 (ru)
JP (2) JP6153921B2 (ru)
KR (2) KR20140027174A (ru)
CN (2) CN103748270B (ru)
AU (2) AU2012230880B2 (ru)
BR (2) BR112013024453A2 (ru)
CL (2) CL2013002732A1 (ru)
CO (2) CO6870029A2 (ru)
EA (2) EA032582B1 (ru)
HK (1) HK1197088A1 (ru)
MX (2) MX2013011000A (ru)
TW (2) TWI630389B (ru)
WO (2) WO2012129423A2 (ru)

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US20120270741A1 (en) 2012-10-25
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KR20140027174A (ko) 2014-03-06
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EP2689053A2 (en) 2014-01-29
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