EA201390626A1 - Производные гидроксамовой кислоты и применение указанных производных в лечении бактериальных инфекций - Google Patents
Производные гидроксамовой кислоты и применение указанных производных в лечении бактериальных инфекцийInfo
- Publication number
- EA201390626A1 EA201390626A1 EA201390626A EA201390626A EA201390626A1 EA 201390626 A1 EA201390626 A1 EA 201390626A1 EA 201390626 A EA201390626 A EA 201390626A EA 201390626 A EA201390626 A EA 201390626A EA 201390626 A1 EA201390626 A1 EA 201390626A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- derivatives
- bacterial infections
- treatment
- application
- hydroxamic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41231110P | 2010-11-10 | 2010-11-10 | |
| PCT/US2011/059280 WO2012154204A1 (en) | 2010-11-10 | 2011-11-04 | Hydroxamic acid derivatives and their use in the treatment of bacterial infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201390626A1 true EA201390626A1 (ru) | 2013-12-30 |
Family
ID=46317476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201390626A EA201390626A1 (ru) | 2010-11-10 | 2011-11-04 | Производные гидроксамовой кислоты и применение указанных производных в лечении бактериальных инфекций |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP2638006A1 (https=) |
| JP (1) | JP2014501716A (https=) |
| KR (1) | KR20140023869A (https=) |
| CN (1) | CN103298780A (https=) |
| AR (1) | AR083760A1 (https=) |
| AU (1) | AU2011367819A1 (https=) |
| BR (1) | BR112013011693A2 (https=) |
| CA (1) | CA2817211A1 (https=) |
| EA (1) | EA201390626A1 (https=) |
| IL (1) | IL226270A0 (https=) |
| MX (1) | MX2013005200A (https=) |
| SG (1) | SG190243A1 (https=) |
| TW (1) | TW201249786A (https=) |
| WO (1) | WO2012154204A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI519508B (zh) | 2007-06-12 | 2016-02-01 | Achaogen Inc | 抗菌劑 |
| EP2847162A1 (en) * | 2012-05-09 | 2015-03-18 | Achaogen, Inc. | Antibacterial agents |
| EP2847168A1 (en) | 2012-05-10 | 2015-03-18 | Achaogen, Inc. | Antibacterial agents |
| AR097617A1 (es) | 2013-09-13 | 2016-04-06 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos del 2h-indazol |
| EA030730B1 (ru) | 2013-12-19 | 2018-09-28 | Идорсиа Фармасьютиклз Лтд | Антибактериальные производные 1h-индазола и 1h-индола |
| AR099612A1 (es) | 2014-03-04 | 2016-08-03 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona |
| US9539305B1 (en) | 2014-03-14 | 2017-01-10 | Fleurir Abx Llc | Pristinamycin compositions, LpxC compositions, their improvements, and combinations thereof |
| CA2948077A1 (en) | 2014-05-16 | 2015-11-19 | Actelion Pharmaceuticals Ltd | Antibacterial quinazoline-4(3h)-one derivatives |
| KR20170086079A (ko) | 2014-11-19 | 2017-07-25 | 액테리온 파마슈티칼 리미티드 | 항균성 벤조티아졸 유도체 |
| DK3233843T3 (da) | 2014-12-16 | 2019-11-18 | Novartis Ag | Isoxazol-hydraxamsyreforbindelser som LPXC-hæmmere |
| EP4286001A3 (en) | 2016-04-25 | 2024-07-17 | Duke University | Benzoylglycine derivatives and methods of making and using same |
| JP6941630B2 (ja) | 2016-06-14 | 2021-09-29 | ノバルティス アーゲー | 抗菌剤としての（ｒ）−４（５−（シクロプロピルエチニル）イソオキサゾール−３−イル）−ｎ−ヒドロキシ−２−メチル−２−（メチルスルホニル）ブタンアミドの結晶形 |
| AR108864A1 (es) | 2016-06-23 | 2018-10-03 | Achaogen Inc | Agentes antibacterianos |
| BR112020016270A2 (pt) * | 2018-02-10 | 2020-12-15 | Kbp Biosciences Co., Ltd. | Composto atuando como antibióticos |
| CN110563611B (zh) * | 2019-09-19 | 2021-02-02 | 中国医学科学院医药生物技术研究所 | 一种异羟肟酸类衍生物及其制备方法和应用 |
| CN113957098A (zh) * | 2021-09-13 | 2022-01-21 | 湖南工业大学 | 普罗威登斯属细菌菌株在制备二价锰氧化剂中的应用 |
| CN116730870B (zh) * | 2023-08-08 | 2023-10-13 | 中国医学科学院医药生物技术研究所 | 异羟肟酸类化合物或其可药用盐、及其用途和制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5925659A (en) | 1996-05-07 | 1999-07-20 | Merck & Co., Inc. | Antibacterial agents |
| AU5426398A (en) | 1996-10-28 | 1998-05-22 | Versicor Inc | Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof |
| EP1169031A1 (en) | 1999-04-09 | 2002-01-09 | British Biotech Pharmaceuticals Limited | Antimicrobial agents |
| KR101076018B1 (ko) * | 2003-01-08 | 2011-10-21 | 유니버시티 오브 워싱톤 | 항균제 |
| DE102006032709A1 (de) | 2006-07-14 | 2008-01-17 | BSH Bosch und Siemens Hausgeräte GmbH | Luftschallgedämmte Lebensmittelmühle |
| CN101209974A (zh) * | 2006-12-31 | 2008-07-02 | 天津药物研究院 | 异羟肟酸类衍生物及其用途 |
| TWI519508B (zh) | 2007-06-12 | 2016-02-01 | Achaogen Inc | 抗菌劑 |
| WO2011005355A1 (en) * | 2009-05-07 | 2011-01-13 | Achaogen, Inc. | Combinations comprising a lpxc inhibitor and an antibiotic for use in the treatment of infections caused by gram-negative bacteria |
| WO2011132712A1 (ja) * | 2010-04-20 | 2011-10-27 | 大正製薬株式会社 | 新規なヒドロキサム酸誘導体 |
-
2011
- 2011-11-04 MX MX2013005200A patent/MX2013005200A/es not_active Application Discontinuation
- 2011-11-04 SG SG2013036272A patent/SG190243A1/en unknown
- 2011-11-04 WO PCT/US2011/059280 patent/WO2012154204A1/en not_active Ceased
- 2011-11-04 AR ARP110104117A patent/AR083760A1/es not_active Application Discontinuation
- 2011-11-04 BR BR112013011693A patent/BR112013011693A2/pt not_active IP Right Cessation
- 2011-11-04 CA CA2817211A patent/CA2817211A1/en not_active Abandoned
- 2011-11-04 KR KR1020137012799A patent/KR20140023869A/ko not_active Withdrawn
- 2011-11-04 TW TW100140449A patent/TW201249786A/zh unknown
- 2011-11-04 EP EP11849908.6A patent/EP2638006A1/en not_active Withdrawn
- 2011-11-04 JP JP2013538794A patent/JP2014501716A/ja active Pending
- 2011-11-04 EA EA201390626A patent/EA201390626A1/ru unknown
- 2011-11-04 AU AU2011367819A patent/AU2011367819A1/en not_active Abandoned
- 2011-11-04 CN CN2011800639128A patent/CN103298780A/zh active Pending
-
2013
- 2013-05-09 IL IL226270A patent/IL226270A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2011367819A1 (en) | 2013-05-02 |
| MX2013005200A (es) | 2013-06-28 |
| KR20140023869A (ko) | 2014-02-27 |
| CA2817211A1 (en) | 2012-11-15 |
| TW201249786A (en) | 2012-12-16 |
| BR112013011693A2 (pt) | 2016-08-09 |
| SG190243A1 (en) | 2013-06-28 |
| IL226270A0 (en) | 2013-07-31 |
| JP2014501716A (ja) | 2014-01-23 |
| EP2638006A1 (en) | 2013-09-18 |
| WO2012154204A1 (en) | 2012-11-15 |
| AR083760A1 (es) | 2013-03-20 |
| CN103298780A (zh) | 2013-09-11 |
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