EA201390509A1 - Способ активации хелперных т-клеток - Google Patents

Способ активации хелперных т-клеток

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Publication number
EA201390509A1
EA201390509A1 EA201390509A EA201390509A EA201390509A1 EA 201390509 A1 EA201390509 A1 EA 201390509A1 EA 201390509 A EA201390509 A EA 201390509A EA 201390509 A EA201390509 A EA 201390509A EA 201390509 A1 EA201390509 A1 EA 201390509A1
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Eurasian Patent Office
Prior art keywords
hla
molecules
drb1
cells
helper
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EA201390509A
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English (en)
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EA037547B1 (ru
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Харуо Сугияма
Синдзи Сого
Масайоси Сато
Рюки Китамото
Йосихиро Гото
Original Assignee
Интернешнл Инститьют Оф Кэнсер Иммунолоджи, Инк.
Оцука Фармасьютикал Ко., Лтд.
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Publication of EA201390509A1 publication Critical patent/EA201390509A1/ru
Publication of EA037547B1 publication Critical patent/EA037547B1/ru

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Abstract

Настоящее изобретение относится к способу активации хелперных Т-клеток, который предусматривает стадию активации хелперных Т-клеток путем добавления пептида WT1 к антиген-презентирующим клеткам, где пептид WT1 способен связываться с любой молекулой МНС класса II из HLA-DRB1* 0101, молекулы HLA-DRB1* 0401, молекулы HLA-DRB1* 0403, молекулы HLA-DRB1* 0406, молекулы HLA-DRB1* 0803, молекулы HLA-DRB1* 0901, молекулы HLA-DRB1* 1101, молекулы HLA-DRB3* 0202, молекулы HLA-DRB4* 0101, молекулы HLA-DPB1* 0201 или молекулы HLA-DPB1* 0301 и т.п.
EA201390509A 2010-10-05 2011-10-04 Способ активации хелперных т-клеток EA037547B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010225806 2010-10-05
PCT/JP2011/072874 WO2012046730A1 (ja) 2010-10-05 2011-10-04 ヘルパーｔ細胞の活性化方法

Publications (2)

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EA201390509A1 true EA201390509A1 (ru) 2013-08-30
EA037547B1 EA037547B1 (ru) 2021-04-12

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US (2) US10654892B2 (ru)
EP (1) EP2626418B8 (ru)
JP (3) JP6134139B2 (ru)
KR (3) KR102079480B1 (ru)
CN (2) CN103298928B (ru)
AR (1) AR083295A1 (ru)
AU (1) AU2011313327B2 (ru)
BR (1) BR112013008230A2 (ru)
CA (1) CA2813557C (ru)
CO (1) CO6710946A2 (ru)
EA (1) EA037547B1 (ru)
ES (1) ES2849187T3 (ru)
IL (2) IL225536B (ru)
MX (2) MX361299B (ru)
MY (1) MY170306A (ru)
NZ (2) NZ609460A (ru)
SG (3) SG189287A1 (ru)
TW (2) TW201623616A (ru)
WO (1) WO2012046730A1 (ru)
ZA (1) ZA201303056B (ru)

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