EA201390333A1 - Конденсированные триазолы для лечения или профилактики умеренного когнитивного нарушения - Google Patents
Конденсированные триазолы для лечения или профилактики умеренного когнитивного нарушенияInfo
- Publication number
- EA201390333A1 EA201390333A1 EA201390333A EA201390333A EA201390333A1 EA 201390333 A1 EA201390333 A1 EA 201390333A1 EA 201390333 A EA201390333 A EA 201390333A EA 201390333 A EA201390333 A EA 201390333A EA 201390333 A1 EA201390333 A1 EA 201390333A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- breach
- prevention
- treatment
- moderate cognitive
- triazoles
- Prior art date
Links
- 230000001149 cognitive effect Effects 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 150000003852 triazoles Chemical class 0.000 title 1
- 102000002659 Amyloid Precursor Protein Secretases Human genes 0.000 abstract 1
- 108010043324 Amyloid Precursor Protein Secretases Proteins 0.000 abstract 1
- 102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010197064 | 2010-09-02 | ||
| JP2011143548 | 2011-06-28 | ||
| PCT/JP2011/070419 WO2012029991A1 (en) | 2010-09-02 | 2011-09-01 | Fused triazoles for the treatment or prophylaxis of mild cognitive impairment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201390333A1 true EA201390333A1 (ru) | 2013-08-30 |
Family
ID=45094181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201390333A EA201390333A1 (ru) | 2010-09-02 | 2011-09-01 | Конденсированные триазолы для лечения или профилактики умеренного когнитивного нарушения |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US8822699B2 (OSRAM) |
| EP (1) | EP2611805A1 (OSRAM) |
| JP (1) | JP5871909B2 (OSRAM) |
| KR (1) | KR20130139895A (OSRAM) |
| CN (1) | CN103249733A (OSRAM) |
| AR (1) | AR082865A1 (OSRAM) |
| AU (1) | AU2011296887A1 (OSRAM) |
| BR (1) | BR112013004746A2 (OSRAM) |
| CA (1) | CA2809779A1 (OSRAM) |
| CL (1) | CL2013000575A1 (OSRAM) |
| DO (1) | DOP2013000051A (OSRAM) |
| EA (1) | EA201390333A1 (OSRAM) |
| EC (1) | ECSP13012535A (OSRAM) |
| MA (1) | MA34556B1 (OSRAM) |
| MX (1) | MX2013002511A (OSRAM) |
| PE (1) | PE20131305A1 (OSRAM) |
| PH (1) | PH12013500403A1 (OSRAM) |
| SG (1) | SG187917A1 (OSRAM) |
| TW (1) | TW201213327A (OSRAM) |
| UY (1) | UY33586A (OSRAM) |
| WO (1) | WO2012029991A1 (OSRAM) |
| ZA (1) | ZA201301929B (OSRAM) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102482276A (zh) * | 2009-07-13 | 2012-05-30 | 武田药品工业株式会社 | 杂环化合物及其用途 |
| KR20130139895A (ko) * | 2010-09-02 | 2013-12-23 | 다케다 야쿠힌 고교 가부시키가이샤 | 경도인지 장애의 치료 또는 예방용 융합 트리아졸 |
| EP2687528A1 (en) * | 2012-07-17 | 2014-01-22 | Ares Trading S.A. | Fused triazole derivatives as gamma secretase modulators |
| RU2563254C2 (ru) * | 2013-07-08 | 2015-09-20 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Способ получения производных 7-(гетеро)арил-4,5,6,7-тетрагидро[1,2,3]триазоло[1,5-a]пиридина |
| CA2980643C (en) * | 2015-05-12 | 2023-10-17 | E I Du Pont De Nemours And Company | Aryl substituted bicyclic compounds as herbicides |
| US20210079182A1 (en) * | 2019-09-12 | 2021-03-18 | Dupont Electronics, Inc. | Polyimide films and electronic devices |
| WO2023114456A1 (en) * | 2021-12-17 | 2023-06-22 | Athira Pharma, Inc. | Uses of bicyclic compounds for the treatment of diseases |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003523345A (ja) | 2000-02-17 | 2003-08-05 | ブリストル−マイヤーズ スクイブ ファーマ カンパニー | Ａβタンパク質産生の阻害剤としてのスクシノイルアミノ炭素環および複素環 |
| CN102584813B (zh) | 2003-05-14 | 2016-07-06 | Ngc药物公司 | 化合物及其在调节淀粉样蛋白β中的用途 |
| WO2005037832A2 (en) * | 2003-10-15 | 2005-04-28 | Targacept, Inc. | Azabicycyclic compounds for relieving pain and treating central nervous system disorders |
| KR100966749B1 (ko) | 2004-05-26 | 2010-06-30 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 신나미드 화합물 |
| AU2005297966B2 (en) | 2004-10-26 | 2010-12-23 | Eisai R & D Management Co., Ltd. | Amorphous object of cinnamide compound |
| JP2009523170A (ja) | 2006-01-11 | 2009-06-18 | メルク エンド カムパニー インコーポレーテッド | 縮合トリアゾールタキキニン受容体アンダニスト |
| EA016464B1 (ru) | 2006-03-09 | 2012-05-30 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Полициклические производные арилимидазола |
| TWI378091B (en) | 2006-03-09 | 2012-12-01 | Eisai R&D Man Co Ltd | Multi-cyclic cinnamide derivatives |
| TW200808800A (en) | 2006-05-05 | 2008-02-16 | Astrazeneca Ab | MGluR5 modulators V |
| TW200835502A (en) | 2006-12-26 | 2008-09-01 | Daiichi Sankyo Co Ltd | Thiazepine derivatives |
| WO2008077649A1 (en) | 2006-12-26 | 2008-07-03 | Gilead Sciences, Inc. | Pyrido(3,2-d)pyrimidines useful for treating viral infectons |
| EP2117311A4 (en) | 2007-02-08 | 2011-05-11 | Merck Sharp & Dohme | Therapeutic agents |
| US8450343B2 (en) | 2007-12-06 | 2013-05-28 | Xianhai Huang | Gamma secretase modulators |
| TW201030002A (en) | 2009-01-16 | 2010-08-16 | Bristol Myers Squibb Co | Bicyclic compounds for the reduction of beta-amyloid production |
| JP2010197064A (ja) | 2009-02-23 | 2010-09-09 | Chugoku Electric Power Co Inc:The | 直下位置測定装置 |
| SG173710A1 (en) * | 2009-02-26 | 2011-09-29 | Eisai R&D Man Co Ltd | Nitrogen-containing fused heterocyclic compounds and their use as beta amyloid production inhibitors |
| JP2012051807A (ja) | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | アリールイミダゾール化合物 |
| JP2012051806A (ja) * | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | イミダゾリルピラジン誘導体 |
| WO2011002067A1 (ja) | 2009-07-02 | 2011-01-06 | 武田薬品工業株式会社 | 複素環化合物およびその用途 |
| CN102482276A (zh) | 2009-07-13 | 2012-05-30 | 武田药品工业株式会社 | 杂环化合物及其用途 |
| CA2778517A1 (en) | 2009-07-15 | 2011-01-20 | Janssen Pharmaceuticals, Inc. | Substituted triazole and imidazole derivatives as gamma secretase modulators |
| US8637525B2 (en) | 2009-07-31 | 2014-01-28 | Bristol-Myers Squibb Company | Compounds for the reduction of beta-amyloid production |
| TWI468402B (zh) | 2009-07-31 | 2015-01-11 | 必治妥美雅史谷比公司 | 降低β－類澱粉生成之化合物 |
| WO2011016559A1 (ja) | 2009-08-07 | 2011-02-10 | 武田薬品工業株式会社 | 複素環化合物およびその用途 |
| JP2011143548A (ja) | 2010-01-12 | 2011-07-28 | Panasonic Corp | スクリーン印刷機及びスクリーン印刷方法 |
| PH12012501381A1 (en) | 2010-01-15 | 2012-10-22 | Janssen Pharmaceuticals Inc | Novel substituted bicyclic triazole derivatives as gamma secretase modulators |
| KR20130139895A (ko) * | 2010-09-02 | 2013-12-23 | 다케다 야쿠힌 고교 가부시키가이샤 | 경도인지 장애의 치료 또는 예방용 융합 트리아졸 |
-
2011
- 2011-09-01 KR KR1020137008170A patent/KR20130139895A/ko not_active Withdrawn
- 2011-09-01 MA MA35785A patent/MA34556B1/fr unknown
- 2011-09-01 UY UY0001033586A patent/UY33586A/es unknown
- 2011-09-01 BR BR112013004746A patent/BR112013004746A2/pt not_active IP Right Cessation
- 2011-09-01 AU AU2011296887A patent/AU2011296887A1/en not_active Abandoned
- 2011-09-01 SG SG2013012604A patent/SG187917A1/en unknown
- 2011-09-01 PE PE2013000360A patent/PE20131305A1/es not_active Application Discontinuation
- 2011-09-01 PH PH1/2013/500403A patent/PH12013500403A1/en unknown
- 2011-09-01 US US13/223,455 patent/US8822699B2/en not_active Expired - Fee Related
- 2011-09-01 MX MX2013002511A patent/MX2013002511A/es not_active Application Discontinuation
- 2011-09-01 WO PCT/JP2011/070419 patent/WO2012029991A1/en not_active Ceased
- 2011-09-01 CN CN2011800518621A patent/CN103249733A/zh active Pending
- 2011-09-01 US US13/819,239 patent/US8901309B2/en not_active Expired - Fee Related
- 2011-09-01 JP JP2013510386A patent/JP5871909B2/ja not_active Expired - Fee Related
- 2011-09-01 EP EP11791058.8A patent/EP2611805A1/en not_active Withdrawn
- 2011-09-01 TW TW100131443A patent/TW201213327A/zh unknown
- 2011-09-01 CA CA2809779A patent/CA2809779A1/en not_active Abandoned
- 2011-09-01 EA EA201390333A patent/EA201390333A1/ru unknown
- 2011-09-01 AR ARP110103195A patent/AR082865A1/es unknown
-
2013
- 2013-02-28 CL CL2013000575A patent/CL2013000575A1/es unknown
- 2013-03-01 DO DO2013000051A patent/DOP2013000051A/es unknown
- 2013-03-14 ZA ZA2013/01929A patent/ZA201301929B/en unknown
- 2013-03-28 EC ECSP13012535 patent/ECSP13012535A/es unknown
-
2014
- 2014-08-08 US US14/454,993 patent/US20140350260A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2611805A1 (en) | 2013-07-10 |
| KR20130139895A (ko) | 2013-12-23 |
| MA34556B1 (fr) | 2013-09-02 |
| ZA201301929B (en) | 2013-11-27 |
| CA2809779A1 (en) | 2012-03-08 |
| BR112013004746A2 (pt) | 2016-06-07 |
| US8822699B2 (en) | 2014-09-02 |
| CL2013000575A1 (es) | 2013-08-23 |
| MX2013002511A (es) | 2013-07-29 |
| US20130178497A1 (en) | 2013-07-11 |
| DOP2013000051A (es) | 2013-04-30 |
| US8901309B2 (en) | 2014-12-02 |
| PE20131305A1 (es) | 2013-10-31 |
| CN103249733A (zh) | 2013-08-14 |
| US20140350260A1 (en) | 2014-11-27 |
| UY33586A (es) | 2012-03-30 |
| AU2011296887A1 (en) | 2013-04-11 |
| JP5871909B2 (ja) | 2016-03-01 |
| ECSP13012535A (es) | 2013-06-28 |
| TW201213327A (en) | 2012-04-01 |
| JP2013536798A (ja) | 2013-09-26 |
| US20120059030A1 (en) | 2012-03-08 |
| SG187917A1 (en) | 2013-04-30 |
| PH12013500403A1 (en) | 2013-03-25 |
| AR082865A1 (es) | 2013-01-16 |
| WO2012029991A1 (en) | 2012-03-08 |
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