UY33586A - Compuesto heterocíclico y sus usos - Google Patents

Compuesto heterocíclico y sus usos

Info

Publication number
UY33586A
UY33586A UY0001033586A UY33586A UY33586A UY 33586 A UY33586 A UY 33586A UY 0001033586 A UY0001033586 A UY 0001033586A UY 33586 A UY33586 A UY 33586A UY 33586 A UY33586 A UY 33586A
Authority
UY
Uruguay
Prior art keywords
heterocyclic compound
activity
amyloid
symbol
salt
Prior art date
Application number
UY0001033586A
Other languages
English (en)
Inventor
Takai Takafumi
Hoashi Yasutaka
Tsukamoto Tetsuya
Kamata Makoto
Koike Tatsuki
Nakamura Minoru
Tomata Yoshihide
Kajita Yuichi
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45094181&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY33586(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of UY33586A publication Critical patent/UY33586A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La presente invención proporciona un derivado heterociclo que tiene una actividad inhibidora de la producción de amiloide P superior y/o una actividad de modulación de y-secretasa superior, y el uso del mismo. Un compuesto representado por la fórmula (I) donde cada símbolo es como se define en la presente memoria descriptiva, o una sal del mismo.
UY0001033586A 2010-09-02 2011-09-01 Compuesto heterocíclico y sus usos UY33586A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010197064 2010-09-02
JP2011143548 2011-06-28

Publications (1)

Publication Number Publication Date
UY33586A true UY33586A (es) 2012-03-30

Family

ID=45094181

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001033586A UY33586A (es) 2010-09-02 2011-09-01 Compuesto heterocíclico y sus usos

Country Status (21)

Country Link
US (3) US8822699B2 (es)
EP (1) EP2611805A1 (es)
JP (1) JP5871909B2 (es)
KR (1) KR20130139895A (es)
CN (1) CN103249733A (es)
AR (1) AR082865A1 (es)
AU (1) AU2011296887A1 (es)
BR (1) BR112013004746A2 (es)
CA (1) CA2809779A1 (es)
CL (1) CL2013000575A1 (es)
DO (1) DOP2013000051A (es)
EA (1) EA201390333A1 (es)
EC (1) ECSP13012535A (es)
MA (1) MA34556B1 (es)
MX (1) MX2013002511A (es)
PE (1) PE20131305A1 (es)
SG (1) SG187917A1 (es)
TW (1) TW201213327A (es)
UY (1) UY33586A (es)
WO (1) WO2012029991A1 (es)
ZA (1) ZA201301929B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2455380A4 (en) * 2009-07-13 2012-11-28 Takeda Pharmaceutical Heterocyclic compound and its use
US8822699B2 (en) * 2010-09-02 2014-09-02 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
EP2687528A1 (en) * 2012-07-17 2014-01-22 Ares Trading S.A. Fused triazole derivatives as gamma secretase modulators
RU2563254C2 (ru) * 2013-07-08 2015-09-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ получения производных 7-(гетеро)арил-4,5,6,7-тетрагидро[1,2,3]триазоло[1,5-a]пиридина
WO2016182780A1 (en) * 2015-05-12 2016-11-17 E I Du Pont De Nemours And Company Aryl substituted bicyclic compounds as herbicides
US11603440B2 (en) * 2019-09-12 2023-03-14 Dupont Electronics, Inc. Polyimide films and electronic devices
WO2023114456A1 (en) * 2021-12-17 2023-06-22 Athira Pharma, Inc. Uses of bicyclic compounds for the treatment of diseases

Family Cites Families (27)

* Cited by examiner, † Cited by third party
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AU2001239791A1 (en) 2000-02-17 2001-08-27 Du Pont Pharmaceuticals Company Succinoylamino carbocycles and heterocycles as inhibitors of abeta protein production
MXPA05012281A (es) 2003-05-14 2006-05-19 Torreypines Therapeutics Inc Compuestos y uso de los mismos en la modulacion beta amiloide.
DE602004024565D1 (de) * 2003-10-15 2010-01-21 Targacept Inc Azabicyclische verbindungen zur linderung von schmerzen und zur behandlung von erkrankungen des zentralen nervensystems
WO2005115990A1 (ja) 2004-05-26 2005-12-08 Eisai R & D Management Co., Ltd. シンナミド化合物
EP1808432B1 (en) 2004-10-26 2010-02-24 Eisai R&D Management Co., Ltd. Amorphous form of cinnamide compound
EP1976527A4 (en) 2006-01-11 2009-04-22 Merck & Co Inc CONDENSED TRIAZOL TACHYKININE RECEPTOR ANTAGONISTS
AR059955A1 (es) 2006-03-09 2008-05-14 Eisai R&D Man Co Ltd Compuestos policiclicos no peptidicos, medicamentos que los contienen, y usos para prevenir o tratar enfermedades causadas por la produccion de beta amiloide
TWI378091B (en) 2006-03-09 2012-12-01 Eisai R&D Man Co Ltd Multi-cyclic cinnamide derivatives
TW200808800A (en) 2006-05-05 2008-02-16 Astrazeneca Ab MGluR5 modulators V
WO2008078725A1 (ja) 2006-12-26 2008-07-03 Daiichi Sankyo Company, Limited チアゼピン誘導体
US8143394B2 (en) 2006-12-26 2012-03-27 Gilead Sciences, Inc. Pyrido(3,2-d)pyrimidines useful for treating viral infections
EP2117311A4 (en) 2007-02-08 2011-05-11 Merck Sharp & Dohme THERAPEUTICS
WO2009073777A1 (en) 2007-12-06 2009-06-11 Schering Corporation Gamma secretase modulators
TW201030002A (en) 2009-01-16 2010-08-16 Bristol Myers Squibb Co Bicyclic compounds for the reduction of beta-amyloid production
JP2010197064A (ja) 2009-02-23 2010-09-09 Chugoku Electric Power Co Inc:The 直下位置測定装置
JP2012051807A (ja) 2009-02-26 2012-03-15 Eisai R & D Management Co Ltd アリールイミダゾール化合物
JP2012519152A (ja) * 2009-02-26 2012-08-23 エーザイ・アール・アンド・ディー・マネジメント株式会社 含窒素縮合複素環化合物及びベータアミロイド産生阻害剤としてのその使用
JP2012051806A (ja) 2009-02-26 2012-03-15 Eisai R & D Management Co Ltd イミダゾリルピラジン誘導体
WO2011002067A1 (ja) 2009-07-02 2011-01-06 武田薬品工業株式会社 複素環化合物およびその用途
EP2455380A4 (en) * 2009-07-13 2012-11-28 Takeda Pharmaceutical Heterocyclic compound and its use
EP2454239B1 (en) 2009-07-15 2014-08-13 Janssen Pharmaceuticals Inc. Substituted triazole and imidazole derivatives as gamma secretase modulators
US8637525B2 (en) 2009-07-31 2014-01-28 Bristol-Myers Squibb Company Compounds for the reduction of beta-amyloid production
TWI468402B (zh) 2009-07-31 2015-01-11 必治妥美雅史谷比公司 降低β－類澱粉生成之化合物
WO2011016559A1 (ja) 2009-08-07 2011-02-10 武田薬品工業株式会社 複素環化合物およびその用途
JP2011143548A (ja) 2010-01-12 2011-07-28 Panasonic Corp スクリーン印刷機及びスクリーン印刷方法
CA2784765A1 (en) 2010-01-15 2011-07-21 Janssen Pharmaceuticals, Inc. Novel substituted bicyclic triazole derivatives as gamma secretase modulators
US8822699B2 (en) * 2010-09-02 2014-09-02 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof

Also Published As

Publication number Publication date
MX2013002511A (es) 2013-07-29
CA2809779A1 (en) 2012-03-08
PE20131305A1 (es) 2013-10-31
EP2611805A1 (en) 2013-07-10
WO2012029991A1 (en) 2012-03-08
KR20130139895A (ko) 2013-12-23
AR082865A1 (es) 2013-01-16
TW201213327A (en) 2012-04-01
BR112013004746A2 (pt) 2016-06-07
AU2011296887A1 (en) 2013-04-11
MA34556B1 (fr) 2013-09-02
JP2013536798A (ja) 2013-09-26
CL2013000575A1 (es) 2013-08-23
JP5871909B2 (ja) 2016-03-01
ECSP13012535A (es) 2013-06-28
US8901309B2 (en) 2014-12-02
US8822699B2 (en) 2014-09-02
EA201390333A1 (ru) 2013-08-30
US20120059030A1 (en) 2012-03-08
DOP2013000051A (es) 2013-04-30
ZA201301929B (en) 2013-11-27
CN103249733A (zh) 2013-08-14
SG187917A1 (en) 2013-04-30
US20130178497A1 (en) 2013-07-11
US20140350260A1 (en) 2014-11-27

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