EA200801716A1 - Тиазольные соединения и их применение - Google Patents

Тиазольные соединения и их применение

Info

Publication number
EA200801716A1
EA200801716A1 EA200801716A EA200801716A EA200801716A1 EA 200801716 A1 EA200801716 A1 EA 200801716A1 EA 200801716 A EA200801716 A EA 200801716A EA 200801716 A EA200801716 A EA 200801716A EA 200801716 A1 EA200801716 A1 EA 200801716A1
Authority
EA
Eurasian Patent Office
Prior art keywords
thiazole compounds
application
formula
treatment
relates
Prior art date
Application number
EA200801716A
Other languages
English (en)
Russian (ru)
Inventor
Кингпинг Зенг
Джон Г. Аллен
Мэттью П. Бурбо
Селиа Домингез
Кристофер Х. Фотч
Нианхе Хан
Фанг-Тсао Хонг
Ксин Хуанг
Мэттью Р. Ли
Айвен Ли
Кингийан Лиу
Джеймс Т. Ридер
Сейфу Тадессе
Андрю С. Таскер
Велларкад Н. Висванадхан
Ксиангхонг Ванг
Курт И. Вейлер
Джордж И. Волхитер
Гуомин Яо
Честер Ченгуанг Юан
Original Assignee
Амген Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Амген Инк. filed Critical Амген Инк.
Publication of EA200801716A1 publication Critical patent/EA200801716A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
EA200801716A 2006-01-18 2007-01-11 Тиазольные соединения и их применение EA200801716A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75954606P 2006-01-18 2006-01-18
PCT/US2007/000871 WO2007084391A2 (en) 2006-01-18 2007-01-11 Thiazole compounds as protein kinase b ( pkb) inhibitors

Publications (1)

Publication Number Publication Date
EA200801716A1 true EA200801716A1 (ru) 2009-04-28

Family

ID=38180602

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200801716A EA200801716A1 (ru) 2006-01-18 2007-01-11 Тиазольные соединения и их применение

Country Status (21)

Country Link
US (2) US7514566B2 (US08084479-20111227-C00353.png)
EP (1) EP1981884B1 (US08084479-20111227-C00353.png)
JP (1) JP5199885B2 (US08084479-20111227-C00353.png)
KR (1) KR20080091369A (US08084479-20111227-C00353.png)
CN (1) CN101421265A (US08084479-20111227-C00353.png)
AR (1) AR059064A1 (US08084479-20111227-C00353.png)
AU (1) AU2007207743B2 (US08084479-20111227-C00353.png)
BR (1) BRPI0706621A2 (US08084479-20111227-C00353.png)
CA (1) CA2636077C (US08084479-20111227-C00353.png)
CR (1) CR10211A (US08084479-20111227-C00353.png)
EA (1) EA200801716A1 (US08084479-20111227-C00353.png)
ES (1) ES2389062T3 (US08084479-20111227-C00353.png)
IL (1) IL192751A0 (US08084479-20111227-C00353.png)
MY (1) MY149143A (US08084479-20111227-C00353.png)
NO (1) NO20083572L (US08084479-20111227-C00353.png)
PE (1) PE20071114A1 (US08084479-20111227-C00353.png)
TW (1) TW200738657A (US08084479-20111227-C00353.png)
UA (1) UA91895C2 (US08084479-20111227-C00353.png)
UY (1) UY30098A1 (US08084479-20111227-C00353.png)
WO (1) WO2007084391A2 (US08084479-20111227-C00353.png)
ZA (1) ZA200806386B (US08084479-20111227-C00353.png)

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UA91895C2 (en) 2010-09-10
KR20080091369A (ko) 2008-10-10
NO20083572L (no) 2008-10-17
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US7514566B2 (en) 2009-04-07
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US20070173506A1 (en) 2007-07-26
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CA2636077C (en) 2012-01-03
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