EA200800819A1 - Варианты хвостовой части редокс-активных лекарственных средств для лечения митохондриальных болезней и других состояний и модуляция биомаркеров энергетического обмена - Google Patents

Варианты хвостовой части редокс-активных лекарственных средств для лечения митохондриальных болезней и других состояний и модуляция биомаркеров энергетического обмена

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Publication number
EA200800819A1
EA200800819A1 EA200800819A EA200800819A EA200800819A1 EA 200800819 A1 EA200800819 A1 EA 200800819A1 EA 200800819 A EA200800819 A EA 200800819A EA 200800819 A EA200800819 A EA 200800819A EA 200800819 A1 EA200800819 A1 EA 200800819A1
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EA
Eurasian Patent Office
Prior art keywords
treatment
energy metabolism
redox
versions
modulation
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EA200800819A
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English (en)
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EA021818B1 (ru
Inventor
Гай М. Миллер
Сидней М. Хехт
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Эдисон Фармасьютикалз, Инк.
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Application filed by Эдисон Фармасьютикалз, Инк. filed Critical Эдисон Фармасьютикалз, Инк.
Publication of EA200800819A1 publication Critical patent/EA200800819A1/ru
Publication of EA021818B1 publication Critical patent/EA021818B1/ru

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Abstract

Раскрыты способы лечения или подавления митохондриальных болезней, таких как атаксия Фридриха (FRDA), наследственная нейропатия зрительного нерва Лебера (LHON), митохондриальная миопатия, энцефалопатия, лактацидоз, инсульт (MELAS) или синдром Кернса-Сейра (KSS), а также соединения, полезные в способах изобретения. Также раскрыты биомаркеры энергетического обмена, полезные для оценки метаболического состояния субъекта и эффективности лечения.
EA200800819A 2005-09-15 2006-09-15 Варианты хвостовой части редокс-активных лекарственных средств для лечения митохондриальных болезней и модуляция биомаркера энергетического обмена q10 EA021818B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71767805P 2005-09-15 2005-09-15
PCT/US2006/036052 WO2007035496A1 (en) 2005-09-15 2006-09-15 Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers

Publications (2)

Publication Number Publication Date
EA200800819A1 true EA200800819A1 (ru) 2008-08-29
EA021818B1 EA021818B1 (ru) 2015-09-30

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EA200800819A EA021818B1 (ru) 2005-09-15 2006-09-15 Варианты хвостовой части редокс-активных лекарственных средств для лечения митохондриальных болезней и модуляция биомаркера энергетического обмена q10

Country Status (14)

Country Link
US (1) US7432305B2 (ru)
EP (1) EP1933821B1 (ru)
JP (5) JP2009508867A (ru)
CA (1) CA2622523C (ru)
CY (1) CY1123740T1 (ru)
DK (1) DK1933821T3 (ru)
EA (1) EA021818B1 (ru)
ES (1) ES2823728T3 (ru)
HU (1) HUE052377T2 (ru)
LT (1) LT1933821T (ru)
PL (1) PL1933821T3 (ru)
PT (1) PT1933821T (ru)
SI (1) SI1933821T1 (ru)
WO (1) WO2007035496A1 (ru)

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