EA200700357A1 - Антимикробная композиция для перорального введения - Google Patents

Антимикробная композиция для перорального введения

Info

Publication number
EA200700357A1
EA200700357A1 EA200700357A EA200700357A EA200700357A1 EA 200700357 A1 EA200700357 A1 EA 200700357A1 EA 200700357 A EA200700357 A EA 200700357A EA 200700357 A EA200700357 A EA 200700357A EA 200700357 A1 EA200700357 A1 EA 200700357A1
Authority
EA
Eurasian Patent Office
Prior art keywords
antimicrobial composition
composition
lactulose
oral administration
antibiotic
Prior art date
Application number
EA200700357A
Other languages
English (en)
Other versions
EA010199B1 (ru
Inventor
Николай Александрович Киселёв
Дмитрий Сергеевич Чичерин
Original Assignee
Николай Александрович Киселёв
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36000449&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200700357(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Николай Александрович Киселёв filed Critical Николай Александрович Киселёв
Publication of EA010199B1 publication Critical patent/EA010199B1/ru
Publication of EA200700357A1 publication Critical patent/EA200700357A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Изобретение относится к области медицины и химико-фармацевтической промышленности и касается препаративных форм антибиотиков. Антимикробная композиция содержит антибиотик, выбранный из группы: линкозамиды, пенициллины широкого спектра действия, цефалоспорины, макролиды, тетрациклины, и лактулозу при соотношении активных компонентов 1:1-1:100. Средний размер частиц лактулозы составляет 100 нм-200 мкм. Возможно выполнение композиции в твердой форме и в форме сиропа или суспензии. При необходимости в композицию могут быть введены фармацевтически приемлемые эксципиенты для придания приемлемой для перорального введения формы.
EA200700357A 2004-08-30 2005-08-25 Антимикробная композиция для перорального введения EA200700357A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2004126203/15A RU2284832C2 (ru) 2004-08-30 2004-08-30 Антимикробная композиция для перорального введения
PCT/RU2005/000434 WO2006025767A2 (fr) 2004-08-30 2005-08-25 Composition antimicrobienne destinee a une administration perorale

Publications (2)

Publication Number Publication Date
EA010199B1 EA010199B1 (ru) 2008-06-30
EA200700357A1 true EA200700357A1 (ru) 2008-06-30

Family

ID=36000449

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200700357A EA200700357A1 (ru) 2004-08-30 2005-08-25 Антимикробная композиция для перорального введения

Country Status (21)

Country Link
US (1) US8231871B2 (ru)
EP (1) EP1790357B1 (ru)
JP (1) JP5062480B2 (ru)
CN (1) CN101031321B (ru)
AT (1) ATE410185T1 (ru)
AU (1) AU2005280704B2 (ru)
BR (1) BRPI0514708A (ru)
CA (1) CA2620919C (ru)
DE (1) DE602005010280D1 (ru)
DK (1) DK1790357T3 (ru)
EA (1) EA200700357A1 (ru)
ES (1) ES2314708T3 (ru)
MX (1) MX2007002291A (ru)
NZ (1) NZ554212A (ru)
PL (1) PL1790357T3 (ru)
PT (1) PT1790357E (ru)
RU (1) RU2284832C2 (ru)
TR (1) TR200703565T1 (ru)
UA (1) UA85608C2 (ru)
WO (1) WO2006025767A2 (ru)
ZA (1) ZA200704449B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7485319B2 (en) 2003-07-25 2009-02-03 Warner Chilcott Company, Inc. Doxycycline metal complex in a solid dosage form
JP5235416B2 (ja) * 2005-01-21 2013-07-10 ワーナー・チルコット・カンパニー・エルエルシー 固体投与形中のテトラサイクリン金属錯体
EA020023B1 (ru) 2008-03-18 2014-08-29 Александр Владимирович ДИКОВСКИЙ Фармацевтическая композиция и способ профилактики дисбиозов, ассоциированных с энтеральным приемом антибиотиков
US20110033526A1 (en) * 2008-03-18 2011-02-10 Aleksander Vladimirovich Dikovskiy Pharmaceutical composition of antibiotics and prebiotics for preventing and treating dysbiosis during antibacterial therapy
CA2911303C (en) 2013-05-07 2021-02-16 Micronics, Inc. Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
CN113476472A (zh) * 2021-07-22 2021-10-08 中国科学院烟台海岸带研究所 一种用于缓解肠道紊乱的益生元组合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1582068A (en) * 1977-12-09 1980-12-31 Morinaga Milk Industry Co Ltd Powder composition comprising viable bifidobacteria cells containing powder and lactulose containing powder
DE3577656D1 (de) * 1984-07-23 1990-06-21 Lilly Co Eli Pharmazeutische zusammensetzungen von ceftazidim.
US4963141A (en) * 1985-08-16 1990-10-16 Alza Corporation Dispensing system for administering beneficial agent formulation to ruminants
JPH0614862B2 (ja) * 1987-05-22 1994-03-02 東京田辺製薬株式会社 ビフィドバクテリウム菌の増殖促進剤
JPS6483025A (en) * 1987-09-24 1989-03-28 Fujio Hayashi Blended preparation of drug-resistant live bacterium agent for controlling intestinal function and antibacterial agent
IL89624A0 (en) * 1988-03-18 1989-09-10 Duphar Int Res Preparation of solid lactulose
FI87880C (fi) * 1990-06-27 1993-03-10 Valio Meijerien Foder som befraemjar tillvaexten och tarmfunktionen hos djur
CN1072964C (zh) * 1994-04-22 2001-10-17 山之内制药株式会社 结肠特异性释药系统
EP0918513B1 (de) * 1996-08-15 2000-12-06 Losan Pharma GmbH Gut schluckbare orale arzneiform
JPH10194975A (ja) * 1997-01-10 1998-07-28 Morinaga Milk Ind Co Ltd 肝疾患治療剤
IT1297538B1 (it) * 1997-08-01 1999-12-17 Francesco Vicidomini Enteroclisma di lattulosio/lattitolo con o senza aggiunta di neomicina per la cura della encefalopatia portosistemica acuta
FR2769839B1 (fr) * 1997-10-21 1999-12-17 Odette Mercedes Salsarulo Composition anhydre a base de lactulose
US6368591B2 (en) * 1998-05-15 2002-04-09 Shanghai Sine Pharmaceutical Corporation Ltd. Beneficial microbe composition, new protective materials for the microbes, method to prepare the same and uses thereof
RU2131260C1 (ru) * 1998-10-14 1999-06-10 Плисов Николай Валерьевич Препарат для лечения желудочно-кишечных заболеваний
IL145187A0 (en) * 1999-03-03 2002-06-30 Lilly Co Eli Echinocandin/carbohydrate complexes
EP1184038B1 (en) * 1999-06-09 2005-12-28 Mochida Pharmaceutical Co., Ltd. System for release in lower digestive tract

Also Published As

Publication number Publication date
EP1790357A2 (en) 2007-05-30
AU2005280704B2 (en) 2010-10-07
DE602005010280D1 (de) 2008-11-20
NZ554212A (en) 2009-08-28
ATE410185T1 (de) 2008-10-15
CN101031321B (zh) 2010-12-15
CN101031321A (zh) 2007-09-05
WO2006025767A3 (fr) 2006-08-17
EA010199B1 (ru) 2008-06-30
RU2004126203A (ru) 2006-02-10
JP5062480B2 (ja) 2012-10-31
PL1790357T3 (pl) 2009-03-31
WO2006025767A2 (fr) 2006-03-09
US8231871B2 (en) 2012-07-31
RU2284832C2 (ru) 2006-10-10
UA85608C2 (ru) 2009-02-10
EP1790357B1 (en) 2008-10-08
US20070254023A1 (en) 2007-11-01
EP1790357A4 (en) 2007-11-07
DK1790357T3 (da) 2009-02-02
MX2007002291A (es) 2008-02-12
PT1790357E (pt) 2008-12-31
CA2620919C (en) 2014-10-14
JP2008511622A (ja) 2008-04-17
BRPI0514708A (pt) 2008-06-24
WO2006025767A8 (fr) 2007-04-05
AU2005280704A1 (en) 2006-03-09
ES2314708T3 (es) 2009-03-16
CA2620919A1 (en) 2006-03-09
TR200703565T1 (tr) 2007-08-21
ZA200704449B (en) 2008-08-27

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): KG TJ TM RU

QB4A Registration of a licence in a contracting state
NF4A Restoration of lapsed right to a eurasian patent

Designated state(s): TJ TM

QB4A Registration of a licence in a contracting state
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ