CA2326048A1 - Peroral active agent suspension - Google Patents

Peroral active agent suspension

Info

Publication number
CA2326048A1
CA2326048A1 CA002326048A CA2326048A CA2326048A1 CA 2326048 A1 CA2326048 A1 CA 2326048A1 CA 002326048 A CA002326048 A CA 002326048A CA 2326048 A CA2326048 A CA 2326048A CA 2326048 A1 CA2326048 A1 CA 2326048A1
Authority
CA
Canada
Prior art keywords
active agent
agent suspension
small amounts
peroral
peroral active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002326048A
Other languages
French (fr)
Other versions
CA2326048C (en
Inventor
Dietrich Turck
Veit Schmelmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2326048A1 publication Critical patent/CA2326048A1/en
Application granted granted Critical
Publication of CA2326048C publication Critical patent/CA2326048C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

The present invention relates to orally administered suspensions of pharmaceutical active substances of the NSAID type, particularly the antirheumatic agent meloxicam, which are stabilised by the addition of small amounts of highly dispersed silicon dioxide using high shear forces and adding small amounts of hydrophilic polymers to form a three-dimensional siloid structure, and a process for the preparation thereof.
CA002326048A 1998-03-27 1999-03-23 Peroral active agent suspension Expired - Lifetime CA2326048C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98105568.4 1998-03-27
EP98105568A EP0945131A1 (en) 1998-03-27 1998-03-27 Peroral drug suspension
PCT/EP1999/001948 WO1999049845A1 (en) 1998-03-27 1999-03-23 Peroral active agent suspension

Publications (2)

Publication Number Publication Date
CA2326048A1 true CA2326048A1 (en) 1999-10-07
CA2326048C CA2326048C (en) 2008-08-12

Family

ID=8231651

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002326048A Expired - Lifetime CA2326048C (en) 1998-03-27 1999-03-23 Peroral active agent suspension

Country Status (26)

Country Link
EP (2) EP0945131A1 (en)
JP (1) JP3323189B2 (en)
KR (1) KR100587208B1 (en)
CN (1) CN1150888C (en)
AR (1) AR016196A1 (en)
AT (1) ATE225648T1 (en)
AU (1) AU762464B2 (en)
BR (1) BR9909189A (en)
CA (1) CA2326048C (en)
CO (1) CO5070601A1 (en)
DE (1) DE59903023D1 (en)
DK (1) DK1066029T3 (en)
ES (1) ES2184428T3 (en)
HK (1) HK1034184A1 (en)
HU (1) HU228474B1 (en)
IL (1) IL137479A (en)
MY (1) MY124599A (en)
NO (1) NO321401B1 (en)
NZ (1) NZ507610A (en)
PL (1) PL192969B1 (en)
PT (1) PT1066029E (en)
TR (1) TR200002772T2 (en)
TW (1) TWI232759B (en)
UY (1) UY25443A1 (en)
WO (1) WO1999049845A1 (en)
ZA (1) ZA200003951B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9956288B2 (en) 2000-06-20 2018-05-01 Boehringer Ingelheim Vetmedica Gmbh Highly concentrated stable meloxicam solutions
US10548901B2 (en) 2004-02-23 2020-02-04 Boehringer Ingelheim Vetmedica Gmbh Meloxicam for the treatment of respiratory diseases in pigs

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8231899B2 (en) 1998-09-10 2012-07-31 Nycomed Danmark Aps Quick release pharmaceutical compositions of drug substances
DE10161077A1 (en) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Highly concentrated stable meloxicam solutions for needleless injection
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
US8512727B2 (en) * 2003-03-03 2013-08-20 Alkermes Pharma Ireland Limited Nanoparticulate meloxicam formulations
EP1938803A3 (en) * 2003-03-03 2010-10-27 Elan Pharma International Limited Formulations comprising nanoparticulate meloxican
US20100297252A1 (en) 2003-03-03 2010-11-25 Elan Pharma International Ltd. Nanoparticulate meloxicam formulations
AU2003100262B4 (en) * 2003-04-07 2003-09-18 Jurox Pty Ltd Stable carprofen composition
US20050158367A1 (en) * 2004-01-16 2005-07-21 The Procter & Gamble Company Liquid compositions comprising one or more medicaments
WO2006042381A1 (en) * 2004-10-21 2006-04-27 Parnell Laboratories (Aust) Pty Limited Anti-inflammatory preparation
US7705000B2 (en) * 2004-12-06 2010-04-27 Janssen Pharmaceutica N.V. Oral suspension comprising meloxicam
GB2438287A (en) 2006-05-19 2007-11-21 Norbrook Lab Ltd Stable aqueous suspension
US9101529B2 (en) 2009-10-12 2015-08-11 Boehringer Ingelheim Vetmedica Gmbh Containers for compositions comprising meloxicam
US20110218191A1 (en) * 2010-03-03 2011-09-08 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the long term-treatment of kidney disorders in cats
KR20130037237A (en) 2010-03-03 2013-04-15 베링거잉겔하임베트메디카게엠베하 Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
EP2544660B1 (en) * 2010-03-10 2018-06-13 Lupin Limited Rifaximin ready-to-use suspension
SG10201502079VA (en) * 2010-03-19 2015-06-29 Boston Biomedical Inc Novel compounds and compositions for targeting cancer stem cells
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
GB201117858D0 (en) 2011-10-17 2011-11-30 Norbrook Lab Ltd Paste
JP5908119B2 (en) * 2012-12-19 2016-04-26 三菱電機株式会社 Air conditioner
CN107529789A (en) 2015-04-28 2018-01-02 马斯公司 The method for preparing sterilizing wet pet foodstuffs
KR102145022B1 (en) * 2018-08-14 2020-08-14 동아제약 주식회사 Suspension composition and dosage form of ibuprofen
CN112044605B (en) * 2019-06-06 2022-06-21 钟志勇 Titanium selection medicament and titanium selection method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196307B (en) * 1984-10-22 1988-11-16 Chiesi Farma Spa AQUEOUS PHARMACEUTICAL FORMULATIONS OF PIROXICAM MONOHYDRATE
US4835187A (en) * 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
JP2860729B2 (en) * 1992-03-10 1999-02-24 エスエス製薬株式会社 Planoprofen suspension syrup
GB2318511A (en) * 1996-10-23 1998-04-29 Eurand Int Process for the preparation of a pharmaceutical composition for rapid suspension in water

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9956288B2 (en) 2000-06-20 2018-05-01 Boehringer Ingelheim Vetmedica Gmbh Highly concentrated stable meloxicam solutions
US10548901B2 (en) 2004-02-23 2020-02-04 Boehringer Ingelheim Vetmedica Gmbh Meloxicam for the treatment of respiratory diseases in pigs
US11083731B2 (en) 2004-02-23 2021-08-10 Boehringer Ingelheim Vetmedica Gmbh Meloxicam for the treatment of respiratory diseases in pigs

Also Published As

Publication number Publication date
UY25443A1 (en) 1999-11-17
BR9909189A (en) 2000-12-05
EP0945131A1 (en) 1999-09-29
EP1066029A1 (en) 2001-01-10
CA2326048C (en) 2008-08-12
ZA200003951B (en) 2002-01-18
DK1066029T3 (en) 2003-01-27
MY124599A (en) 2006-06-30
PL342345A1 (en) 2001-06-04
HUP0102036A3 (en) 2002-12-28
TR200002772T2 (en) 2000-12-21
NO321401B1 (en) 2006-05-08
AU762464B2 (en) 2003-06-26
ES2184428T3 (en) 2003-04-01
AR016196A1 (en) 2001-06-20
WO1999049845A1 (en) 1999-10-07
HU228474B1 (en) 2013-03-28
CN1295462A (en) 2001-05-16
CN1150888C (en) 2004-05-26
HK1034184A1 (en) 2001-10-19
KR100587208B1 (en) 2006-06-08
JP3323189B2 (en) 2002-09-09
CO5070601A1 (en) 2001-08-28
EP1066029B1 (en) 2002-10-09
IL137479A0 (en) 2001-07-24
NO20004822L (en) 2000-11-23
DE59903023D1 (en) 2002-11-14
PT1066029E (en) 2003-02-28
NO20004822D0 (en) 2000-09-26
TWI232759B (en) 2005-05-21
HUP0102036A2 (en) 2002-03-28
NZ507610A (en) 2003-08-29
AU3147099A (en) 1999-10-18
PL192969B1 (en) 2006-12-29
IL137479A (en) 2005-09-25
JP2002509875A (en) 2002-04-02
ATE225648T1 (en) 2002-10-15
KR20010042197A (en) 2001-05-25

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20190325