RU2004126203A - Антимикробная композиция для перорального введения - Google Patents

Антимикробная композиция для перорального введения Download PDF

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Publication number
RU2004126203A
RU2004126203A RU2004126203/15A RU2004126203A RU2004126203A RU 2004126203 A RU2004126203 A RU 2004126203A RU 2004126203/15 A RU2004126203/15 A RU 2004126203/15A RU 2004126203 A RU2004126203 A RU 2004126203A RU 2004126203 A RU2004126203 A RU 2004126203A
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RU
Russia
Prior art keywords
antimicrobial composition
composition according
lactulose
oral administration
composition
Prior art date
Application number
RU2004126203/15A
Other languages
English (en)
Other versions
RU2284832C2 (ru
Inventor
Николай Александрович Киселев (RU)
Николай Александрович Киселев
Дмитрий Сергеевич Чигерин (RU)
Дмитрий Сергеевич Чигерин
Original Assignee
Николай Александрович Киселев (RU)
Николай Александрович Киселев
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36000449&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2004126203(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Николай Александрович Киселев (RU), Николай Александрович Киселев filed Critical Николай Александрович Киселев (RU)
Priority to RU2004126203/15A priority Critical patent/RU2284832C2/ru
Priority to AT05782960T priority patent/ATE410185T1/de
Priority to BRPI0514708-5A priority patent/BRPI0514708A/pt
Priority to PL05782960T priority patent/PL1790357T3/pl
Priority to TR2007/03565T priority patent/TR200703565T1/xx
Priority to AU2005280704A priority patent/AU2005280704B2/en
Priority to JP2007529762A priority patent/JP5062480B2/ja
Priority to US11/661,472 priority patent/US8231871B2/en
Priority to PT05782960T priority patent/PT1790357E/pt
Priority to EA200700357A priority patent/EA010199B1/ru
Priority to ES05782960T priority patent/ES2314708T3/es
Priority to DK05782960T priority patent/DK1790357T3/da
Priority to EP05782960A priority patent/EP1790357B1/en
Priority to CN2005800291966A priority patent/CN101031321B/zh
Priority to PCT/RU2005/000434 priority patent/WO2006025767A2/ru
Priority to CA2620919A priority patent/CA2620919C/en
Priority to UAA200702431A priority patent/UA85608C2/ru
Priority to NZ554212A priority patent/NZ554212A/en
Priority to MX2007002291A priority patent/MX2007002291A/es
Priority to DE602005010280T priority patent/DE602005010280D1/de
Publication of RU2004126203A publication Critical patent/RU2004126203A/ru
Publication of RU2284832C2 publication Critical patent/RU2284832C2/ru
Application granted granted Critical
Priority to ZA200704449A priority patent/ZA200704449B/xx

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Claims (8)

1. Антимикробная композиция для перорального введения, отличающаяся тем, что она содержит антибиотик, выбранный из группы, включающей пенициллины широкого спектра действия, цефалоспорины, тетрациклины, линкозамиды, макролиды, и лактулозу при соотношении активных компонентов 1:1-1:100, причем средний размер частиц лактулозы составляет 100 нм-200 мкм.
2. Антимикробная композиция по п.1, отличающаяся тем, что она содержит дополнительно фармацевтически приемлемые вспомогательные вещества.
3. Антимикробная композиция по п.2, отличающаяся тем, что она выполнена в форме таблетки.
4. Антимикробная композиция по п.2, отличающаяся тем, что она выполнена в форме порошка.
5. Антимикробная композиция по п.2, отличающаяся тем, что она выполнена в форме капсулы.
6. Антимикробная композиция по п.2, отличающаяся тем, что она выполнена в форме гранулы.
7. Антимикробная композиция по п.2, отличающаяся тем, что она выполнена в форме сиропа.
8. Антимикробная композиция по п.2, отличающаяся тем, что она выполнена в форме суспензии.
RU2004126203/15A 2004-08-30 2004-08-30 Антимикробная композиция для перорального введения RU2284832C2 (ru)

Priority Applications (21)

Application Number Priority Date Filing Date Title
RU2004126203/15A RU2284832C2 (ru) 2004-08-30 2004-08-30 Антимикробная композиция для перорального введения
ES05782960T ES2314708T3 (es) 2004-08-30 2005-08-25 Composicion antimicrobiana administrble peroralmente.
EP05782960A EP1790357B1 (en) 2004-08-30 2005-08-25 Perorally administrable antimicrobial composition
PL05782960T PL1790357T3 (pl) 2004-08-30 2005-08-25 Kompozycja antybakteryjna do podawania doustnego
TR2007/03565T TR200703565T1 (tr) 2004-08-30 2005-08-25 Peroral uygulanabilir antimikrobiyal kompozisyon.
AU2005280704A AU2005280704B2 (en) 2004-08-30 2005-08-25 Perorally administrable antimicrobial composition
JP2007529762A JP5062480B2 (ja) 2004-08-30 2005-08-25 経口投与可能な抗菌性組成物
US11/661,472 US8231871B2 (en) 2004-08-30 2005-08-25 Perorally administrable antimicrobial composition
PT05782960T PT1790357E (pt) 2004-08-30 2005-08-25 Composição antimicrobiana administrável por via oral
EA200700357A EA010199B1 (ru) 2004-08-30 2005-08-25 Антимикробная композиция для перорального введения
AT05782960T ATE410185T1 (de) 2004-08-30 2005-08-25 Oral verabreichbare antimikrobielle zusammensetzung
DK05782960T DK1790357T3 (da) 2004-08-30 2005-08-25 Peroralt indgivelig antimikrobiel sammensætning
BRPI0514708-5A BRPI0514708A (pt) 2004-08-30 2005-08-25 composição antimicrobiana para administração peroral
CN2005800291966A CN101031321B (zh) 2004-08-30 2005-08-25 口服抗菌组合物
PCT/RU2005/000434 WO2006025767A2 (fr) 2004-08-30 2005-08-25 Composition antimicrobienne destinee a une administration perorale
CA2620919A CA2620919C (en) 2004-08-30 2005-08-25 Perorally administrable antimicrobial composition
UAA200702431A UA85608C2 (ru) 2004-08-30 2005-08-25 Противомикробная композиция для перорального введения c лактулозой
NZ554212A NZ554212A (en) 2004-08-30 2005-08-25 Perorally administrable antimicrobial composition comprising an antibiotic drug and lactulose particles
MX2007002291A MX2007002291A (es) 2004-08-30 2005-08-25 Composicion antimicrobiana administrable oralmente.
DE602005010280T DE602005010280D1 (de) 2004-08-30 2005-08-25 Oral verabreichbare antimikrobielle zusammensetzung
ZA200704449A ZA200704449B (en) 2004-08-30 2007-05-30 Perorally administrable antimicrobial composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2004126203/15A RU2284832C2 (ru) 2004-08-30 2004-08-30 Антимикробная композиция для перорального введения

Publications (2)

Publication Number Publication Date
RU2004126203A true RU2004126203A (ru) 2006-02-10
RU2284832C2 RU2284832C2 (ru) 2006-10-10

Family

ID=36000449

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2004126203/15A RU2284832C2 (ru) 2004-08-30 2004-08-30 Антимикробная композиция для перорального введения

Country Status (21)

Country Link
US (1) US8231871B2 (ru)
EP (1) EP1790357B1 (ru)
JP (1) JP5062480B2 (ru)
CN (1) CN101031321B (ru)
AT (1) ATE410185T1 (ru)
AU (1) AU2005280704B2 (ru)
BR (1) BRPI0514708A (ru)
CA (1) CA2620919C (ru)
DE (1) DE602005010280D1 (ru)
DK (1) DK1790357T3 (ru)
EA (1) EA010199B1 (ru)
ES (1) ES2314708T3 (ru)
MX (1) MX2007002291A (ru)
NZ (1) NZ554212A (ru)
PL (1) PL1790357T3 (ru)
PT (1) PT1790357E (ru)
RU (1) RU2284832C2 (ru)
TR (1) TR200703565T1 (ru)
UA (1) UA85608C2 (ru)
WO (1) WO2006025767A2 (ru)
ZA (1) ZA200704449B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103040773A (zh) 2003-07-25 2013-04-17 沃纳奇尔科特有限责任公司 多西环素金属络合物固体剂型
SG158869A1 (en) * 2005-01-21 2010-02-26 Warner Chilcott Co Llc A tetracycline metal complex in a solid dosage form
CN101998859B (zh) * 2008-03-18 2014-03-05 亚历山大·弗拉基米罗维奇·季科夫斯基 用于预防与抗生素肠道给药相关的生态失调的药物组合物
BRPI0822359A2 (pt) 2008-03-18 2015-07-14 Aleksander Vladimirovich Dikovskiy Composição farmacêutica de antibióticos e prebióticos para prevenir e tratar disbiose durante terapia antibacteriana
WO2014182831A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
CN113476472A (zh) * 2021-07-22 2021-10-08 中国科学院烟台海岸带研究所 一种用于缓解肠道紊乱的益生元组合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1582068A (en) * 1977-12-09 1980-12-31 Morinaga Milk Industry Co Ltd Powder composition comprising viable bifidobacteria cells containing powder and lactulose containing powder
IL75800A (en) * 1984-07-23 1988-11-30 Lilly Co Eli Pharmaceutical formulations comprising ceftazidime pentahydrate and amorphous lactose
US4963141A (en) * 1985-08-16 1990-10-16 Alza Corporation Dispensing system for administering beneficial agent formulation to ruminants
JPH0614862B2 (ja) * 1987-05-22 1994-03-02 東京田辺製薬株式会社 ビフィドバクテリウム菌の増殖促進剤
JPS6483025A (en) * 1987-09-24 1989-03-28 Fujio Hayashi Blended preparation of drug-resistant live bacterium agent for controlling intestinal function and antibacterial agent
NZ228342A (en) * 1988-03-18 1991-03-26 Duphar Int Res Preparing solid form of lactulose from lactulose syrup
FI87880C (fi) * 1990-06-27 1993-03-10 Valio Meijerien Foder som befraemjar tillvaexten och tarmfunktionen hos djur
ES2283503T3 (es) * 1994-04-22 2007-11-01 Astellas Pharma Inc. Sistema de liberacion de farmaco especifico de colon.
US6709678B2 (en) * 1996-08-15 2004-03-23 Losan Pharma Gmbh Easy to swallow oral medicament composition
JPH10194975A (ja) * 1997-01-10 1998-07-28 Morinaga Milk Ind Co Ltd 肝疾患治療剤
IT1297538B1 (it) * 1997-08-01 1999-12-17 Francesco Vicidomini Enteroclisma di lattulosio/lattitolo con o senza aggiunta di neomicina per la cura della encefalopatia portosistemica acuta
FR2769839B1 (fr) * 1997-10-21 1999-12-17 Odette Mercedes Salsarulo Composition anhydre a base de lactulose
US6368591B2 (en) * 1998-05-15 2002-04-09 Shanghai Sine Pharmaceutical Corporation Ltd. Beneficial microbe composition, new protective materials for the microbes, method to prepare the same and uses thereof
RU2131260C1 (ru) * 1998-10-14 1999-06-10 Плисов Николай Валерьевич Препарат для лечения желудочно-кишечных заболеваний
IL145187A0 (en) * 1999-03-03 2002-06-30 Lilly Co Eli Echinocandin/carbohydrate complexes
ATE314091T1 (de) * 1999-06-09 2006-01-15 Mochida Pharm Co Ltd System für wirkstofffreisetzung im unteren verdauungstrakt

Also Published As

Publication number Publication date
JP2008511622A (ja) 2008-04-17
EP1790357A4 (en) 2007-11-07
CA2620919C (en) 2014-10-14
MX2007002291A (es) 2008-02-12
US8231871B2 (en) 2012-07-31
DK1790357T3 (da) 2009-02-02
WO2006025767A3 (fr) 2006-08-17
CN101031321A (zh) 2007-09-05
JP5062480B2 (ja) 2012-10-31
ZA200704449B (en) 2008-08-27
ES2314708T3 (es) 2009-03-16
US20070254023A1 (en) 2007-11-01
WO2006025767A8 (fr) 2007-04-05
ATE410185T1 (de) 2008-10-15
TR200703565T1 (tr) 2007-08-21
PT1790357E (pt) 2008-12-31
DE602005010280D1 (de) 2008-11-20
AU2005280704A1 (en) 2006-03-09
UA85608C2 (ru) 2009-02-10
EP1790357A2 (en) 2007-05-30
EA200700357A1 (ru) 2008-06-30
CN101031321B (zh) 2010-12-15
PL1790357T3 (pl) 2009-03-31
EA010199B1 (ru) 2008-06-30
BRPI0514708A (pt) 2008-06-24
AU2005280704B2 (en) 2010-10-07
NZ554212A (en) 2009-08-28
WO2006025767A2 (fr) 2006-03-09
EP1790357B1 (en) 2008-10-08
RU2284832C2 (ru) 2006-10-10
CA2620919A1 (en) 2006-03-09

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