EA200601648A1 - Глюкозамин и общие пролекарства глюкозамин/противовоспалительный агент, композиции и способы - Google Patents
Глюкозамин и общие пролекарства глюкозамин/противовоспалительный агент, композиции и способыInfo
- Publication number
- EA200601648A1 EA200601648A1 EA200601648A EA200601648A EA200601648A1 EA 200601648 A1 EA200601648 A1 EA 200601648A1 EA 200601648 A EA200601648 A EA 200601648A EA 200601648 A EA200601648 A EA 200601648A EA 200601648 A1 EA200601648 A1 EA 200601648A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- glucosamine
- compositions
- methods
- inflammatory agent
- general procedures
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Birds (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Agronomy & Crop Science (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Neurosurgery (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Предложены общие пролекарства глюкозамина, и производных, и аналогов глюкозамина, и противовоспалительного агента, их композиции и способы, например, лечения расстройств и состояний путем введения этих композиций. Также предложены композиции глюкозамина, и производных, и аналогов глюкозамина для местного применения.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56012804P | 2004-04-07 | 2004-04-07 | |
PCT/US2005/011739 WO2005116086A2 (en) | 2004-04-07 | 2005-04-07 | Glucosamine and glucosamine/anti-inflammatory mutual prodrugs, compositions, and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
EA200601648A1 true EA200601648A1 (ru) | 2007-04-27 |
Family
ID=35451458
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200601648A EA200601648A1 (ru) | 2004-04-07 | 2005-04-07 | Глюкозамин и общие пролекарства глюкозамин/противовоспалительный агент, композиции и способы |
Country Status (15)
Country | Link |
---|---|
US (1) | US8361990B2 (ru) |
EP (1) | EP1742534A4 (ru) |
JP (1) | JP2007532562A (ru) |
KR (1) | KR20060132036A (ru) |
CN (1) | CN1953660A (ru) |
AP (1) | AP2006003774A0 (ru) |
AU (1) | AU2005248294A1 (ru) |
CA (1) | CA2561672A1 (ru) |
DO (1) | DOP2006000252A (ru) |
EA (1) | EA200601648A1 (ru) |
EC (1) | ECSP066972A (ru) |
IL (1) | IL178500A0 (ru) |
MX (1) | MXPA06011475A (ru) |
WO (1) | WO2005116086A2 (ru) |
ZA (1) | ZA200608364B (ru) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005116086A2 (en) | 2004-04-07 | 2005-12-08 | The University Of Georgia Research Foundation, Inc. | Glucosamine and glucosamine/anti-inflammatory mutual prodrugs, compositions, and methods |
US8034796B2 (en) | 2004-04-07 | 2011-10-11 | The University Of Georgia Research Foundation, Inc. | Glucosamine and glucosamine/anti-inflammatory mutual prodrugs, compositions, and methods |
KR100780868B1 (ko) * | 2006-07-10 | 2007-11-30 | 부경대학교 산학협력단 | 항암효과를 나타내는 4급 아미노 글루코사민 화합물 |
EP1902705A1 (en) * | 2006-09-22 | 2008-03-26 | Pharmatex Italia Srl | Injectable pharmaceutical nimesulide solutions |
KR100857509B1 (ko) * | 2007-01-11 | 2008-09-08 | 주식회사 티디에스팜 | 글루코사민을 포함하는 관절염 치료용 경피흡수제제 |
FR2918376B1 (fr) | 2007-07-04 | 2011-10-28 | Mathieu Borge | Compositions liquides ou pateuses destinees a l'apport en elements essentiels a la synthese et a la constitution des proteoglycanes, notamment pour le traitement de la degradation du cartilage |
JP4490498B2 (ja) * | 2008-09-30 | 2010-06-23 | 新田ゼラチン株式会社 | 疾病抑制剤 |
CN101637451B (zh) * | 2009-06-12 | 2011-03-30 | 陶灵刚 | 一种氯诺昔康脂质体药物组合物及其固体制剂 |
FR2958157B1 (fr) * | 2010-04-02 | 2012-06-29 | Libragen | Composition cosmetique et pharmaceutique comprenant du n-acetyl-glucosamine-6-phosphate |
WO2014037832A2 (en) | 2012-09-06 | 2014-03-13 | Mahesh Kandula | Compositions and methods for the treatment of epilepsy and neurological diseases |
JP2015522531A (ja) | 2012-05-07 | 2015-08-06 | セリックスビオ プライヴェート リミテッド | 神経筋疾患及び神経変性疾患の治療のための組成物及び方法 |
US9738631B2 (en) | 2012-05-07 | 2017-08-22 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological disorders |
WO2013167990A1 (en) | 2012-05-07 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of depression |
US9522884B2 (en) | 2012-05-08 | 2016-12-20 | Cellix Bio Private Limited | Compositions and methods for the treatment of metabolic disorders |
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US9403826B2 (en) | 2012-05-08 | 2016-08-02 | Cellix Bio Private Limited | Compositions and methods for the treatment of inflammatory disorders |
US20150148306A1 (en) * | 2012-05-08 | 2015-05-28 | Mahesh Kandula | Compositions and methods for the treatment of inflammation |
US9573927B2 (en) | 2012-05-10 | 2017-02-21 | Cellix Bio Private Limited | Compositions and methods for the treatment of severe pain |
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US20190021995A1 (en) * | 2015-12-30 | 2019-01-24 | Alexander Vilenovich ASAFOV | Formulation for treatment of peripheral joints, spinal joints and/or extracellular matrix elements of connective tissue, method of manufacture and uses |
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CN109929001B (zh) * | 2017-12-18 | 2022-07-08 | 润佳(苏州)医药科技有限公司 | 葡萄糖胺衍生物、其组合物及其医药用途 |
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RU2685436C1 (ru) * | 2018-06-22 | 2019-04-18 | ЗАО "ФармФирма "Сотекс" | Трансдермальный препарат для лечения и профилактики болезней суставов и мягких тканей |
EP4361164A1 (en) * | 2021-06-04 | 2024-05-01 | Risen (Suzhou) Pharma Tech Co., Ltd. | Crystal forms of glucosamine derivative, and preparation method therefor and use thereof |
IT202200004574A1 (it) | 2022-03-10 | 2023-09-10 | Sergio Ammendola | Nanoparticelle di N-acetilglucosammina e loro applicazioni |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2223051C2 (de) | 1972-05-09 | 1983-02-03 | Farmades S.p.A., Rom | Monohydrat des d(+)-Glucosamids der 1-(p-Chlorbenzoyl)2-methyl-5-methoxy-indolyl-3-essigsäure, Verfahren zu seiner Herstellung und pharmazeutische Zubereitung |
GB1383465A (en) * | 1972-05-09 | 1974-02-12 | Sir Labo Chimico Biologi | Glucosamide of 1- p-chlorobenzoyl indolyl-3-acetic acid and processes for its preparation |
JPS5455545A (en) * | 1977-10-12 | 1979-05-02 | Hokuriku Pharmaceutical | Glucosamide derivative |
US4278679A (en) | 1980-05-01 | 1981-07-14 | Chromalloy American Corporation | Combination of two or more drugs in a single dosage form wherein one of the drugs is a physostigmine compound |
US5234767A (en) | 1987-03-13 | 1993-08-10 | Micro-Pak, Inc. | Hybrid paucilamellar lipid vesicles |
US5147723A (en) | 1987-07-28 | 1992-09-15 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
US4855090A (en) | 1987-03-13 | 1989-08-08 | Micro-Pak, Inc. | Method of producing high aqueous volume multilamellar vesicles |
US4917951A (en) | 1987-07-28 | 1990-04-17 | Micro-Pak, Inc. | Lipid vesicles formed of surfactants and steroids |
US5474848A (en) | 1987-03-13 | 1995-12-12 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
US5219538A (en) | 1987-03-13 | 1993-06-15 | Micro-Pak, Inc. | Gas and oxygen carrying lipid vesicles |
US5628936A (en) | 1987-03-13 | 1997-05-13 | Micro-Pak, Inc. | Hybrid paucilamellar lipid vesicles |
US4942038A (en) | 1987-03-13 | 1990-07-17 | Micro Vesicular Systems, Inc. | Encapsulated humectant |
US5000960A (en) | 1987-03-13 | 1991-03-19 | Micro-Pak, Inc. | Protein coupling to lipid vesicles |
US4911928A (en) | 1987-03-13 | 1990-03-27 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
US5032457A (en) | 1988-03-03 | 1991-07-16 | Micro Vesicular Systems, Inc. | Paucilamellar lipid vesicles using charge-localized, single chain, nonphospholipid surfactants |
US5104736A (en) | 1988-03-03 | 1992-04-14 | Micro-Pak, Inc. | Reinforced paucilamellar lipid vesicles |
AU6524990A (en) | 1989-09-21 | 1991-04-18 | Micro Vesicular Systems, Inc. | Hybrid paucilamellar lipid vesicles |
US5358964A (en) | 1993-07-26 | 1994-10-25 | Warner-Lambert Company | Benzylidene-lactone and their thiocarbonyl analogs as inhibitors of proteoglycan degradation |
AU7271996A (en) | 1995-10-23 | 1997-05-15 | Queen's University At Kingston | Method and pharmaceutical composition for chondrostimulation with a prostaglandin (e.g. misoprostol) and tgf-beta, optionally in combination with igf-1 |
US6083996A (en) | 1997-11-05 | 2000-07-04 | Nexmed Holdings, Inc. | Topical compositions for NSAI drug delivery |
EP1024808A1 (en) * | 1998-04-11 | 2000-08-09 | Errekappa Euroterapici S.p.a. | Pharmaceutical preparations containing hydrosoluble ketoprofen salts and their application |
US6656925B2 (en) | 1998-09-09 | 2003-12-02 | Advanced Medical Instruments | Composition and method of treating arthritis |
US6346519B1 (en) | 1998-09-09 | 2002-02-12 | Advanced Medical Instruments | Method and composition for treating arthritis |
US6299902B1 (en) | 1999-05-19 | 2001-10-09 | The University Of Georgia Research Foundation, Inc. | Enhanced transdermal anesthesia of local anesthetic agents |
US6368618B1 (en) | 1999-07-01 | 2002-04-09 | The University Of Georgia Research Foundation, Inc. | Composition and method for enhanced transdermal absorption of nonsteroidal anti-inflammatory drugs |
WO2001041753A2 (en) | 1999-12-07 | 2001-06-14 | Rutgers, The State University Of New Jersey | Therapeutic compositions and methods for treating periodontitis with antiinflamatory compounds |
US20040038948A1 (en) | 1999-12-07 | 2004-02-26 | Uhrich Kathryn E. | Therapeutic compositions and methods |
US6685928B2 (en) | 1999-12-07 | 2004-02-03 | Rutgers, The State University Of New Jersey | Therapeutic compositions and methods |
US6677321B1 (en) | 1999-12-09 | 2004-01-13 | Bruce Levin | Methods and compositions for treatment of inflammatory disease |
AU1953701A (en) | 1999-12-09 | 2001-06-18 | Bruce Levin | Methods and compositions for treatment of inflammatory disease |
WO2003099013A1 (en) * | 2000-01-24 | 2003-12-04 | Omni Nutraceuticals, Inc. | Acetaminophen/non-steroidal anti-inflamatory drug-glucosamine composition |
US20020022052A1 (en) | 2000-04-06 | 2002-02-21 | Dransfield Charles William | Transdermal delivery system |
US6429223B1 (en) | 2000-06-23 | 2002-08-06 | Medinox, Inc. | Modified forms of pharmacologically active agents and uses therefor |
US6355666B1 (en) | 2000-06-23 | 2002-03-12 | Medinox, Inc. | Protected forms of pharmacologically active agents and uses therefor |
CA2317305A1 (en) | 2000-08-29 | 2002-02-28 | Tassos P. Anastassiades | Method of enhancing chondrocyte cell growth and glycosaminoglycan production |
CA2423585A1 (en) * | 2000-09-26 | 2002-04-04 | Temple University Of The Commonwealth System Of Higher Education | Analgesic and glucosamine compositions |
US20020182237A1 (en) | 2001-03-22 | 2002-12-05 | The Procter & Gamble Company | Skin care compositions containing a sugar amine |
US20030105144A1 (en) | 2001-04-17 | 2003-06-05 | Ping Gao | Stabilized oral pharmaceutical composition |
US20030114418A1 (en) * | 2001-08-14 | 2003-06-19 | Pharmacia Corporation | Method for the treatment and prevention of pain and inflammation with glucosamine and a cyclooxygenase-2 selective inhibitor and compositions therefor |
US20050101563A1 (en) | 2001-08-14 | 2005-05-12 | Pharmacia Corporation | Method and compositions for the treatment and prevention of pain and inflammation |
US20030114416A1 (en) | 2001-08-14 | 2003-06-19 | Pharmacia Corporation | Method and compositions for the treatment and prevention of pain and inflammation with a cyclooxygenase-2 selective inhibitor and chondroitin sulfate |
US20030125303A1 (en) | 2001-12-28 | 2003-07-03 | Andrew Kucharchuk | Transdermal formulation for repair and maintenance of connective tissue |
US6579543B1 (en) | 2002-02-22 | 2003-06-17 | Jackie H. McClung | Composition for topical application to skin |
PL373523A1 (en) | 2002-04-22 | 2005-09-05 | Pfizer Products Inc. | Indol-2-ones as selective inhibitors of cyclooxygenase-2 |
US20050215487A1 (en) * | 2002-06-27 | 2005-09-29 | Holick Michael F | Conjugates comprising an nsaid and a sugar and uses thereof |
CA2490190A1 (en) * | 2002-06-27 | 2004-01-08 | A & D Bioscience, Inc. | Conjugates comprising an nsaid and a sugar and uses thereof |
WO2004060346A2 (en) | 2002-12-30 | 2004-07-22 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
CA2417943A1 (en) | 2003-01-31 | 2004-07-31 | Tassos P. Anastassiades | Weight gain and growth stimulation in mammals by n-acylated glucosamines |
US8034796B2 (en) | 2004-04-07 | 2011-10-11 | The University Of Georgia Research Foundation, Inc. | Glucosamine and glucosamine/anti-inflammatory mutual prodrugs, compositions, and methods |
WO2005116086A2 (en) | 2004-04-07 | 2005-12-08 | The University Of Georgia Research Foundation, Inc. | Glucosamine and glucosamine/anti-inflammatory mutual prodrugs, compositions, and methods |
-
2005
- 2005-04-07 WO PCT/US2005/011739 patent/WO2005116086A2/en active Application Filing
- 2005-04-07 AP AP2006003774A patent/AP2006003774A0/xx unknown
- 2005-04-07 CA CA002561672A patent/CA2561672A1/en not_active Abandoned
- 2005-04-07 EA EA200601648A patent/EA200601648A1/ru unknown
- 2005-04-07 KR KR1020067023235A patent/KR20060132036A/ko not_active Application Discontinuation
- 2005-04-07 MX MXPA06011475A patent/MXPA06011475A/es not_active Application Discontinuation
- 2005-04-07 EP EP05778582A patent/EP1742534A4/en not_active Withdrawn
- 2005-04-07 CN CNA2005800141070A patent/CN1953660A/zh active Pending
- 2005-04-07 AU AU2005248294A patent/AU2005248294A1/en not_active Abandoned
- 2005-04-07 JP JP2007507491A patent/JP2007532562A/ja active Pending
-
2006
- 2006-10-05 IL IL178500A patent/IL178500A0/en unknown
- 2006-10-06 ZA ZA200608364A patent/ZA200608364B/en unknown
- 2006-11-08 EC EC2006006972A patent/ECSP066972A/es unknown
- 2006-11-15 DO DO2006P000252A patent/DOP2006000252A/es unknown
-
2011
- 2011-09-09 US US13/229,049 patent/US8361990B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US8361990B2 (en) | 2013-01-29 |
IL178500A0 (en) | 2007-02-11 |
CA2561672A1 (en) | 2005-12-08 |
US20120021046A1 (en) | 2012-01-26 |
EP1742534A4 (en) | 2011-04-13 |
CN1953660A (zh) | 2007-04-25 |
MXPA06011475A (es) | 2007-04-25 |
KR20060132036A (ko) | 2006-12-20 |
AP2006003774A0 (en) | 2006-10-31 |
JP2007532562A (ja) | 2007-11-15 |
DOP2006000252A (es) | 2007-09-30 |
ECSP066972A (es) | 2007-03-29 |
WO2005116086A3 (en) | 2006-08-24 |
AU2005248294A1 (en) | 2005-12-08 |
ZA200608364B (en) | 2008-06-25 |
WO2005116086A2 (en) | 2005-12-08 |
EP1742534A2 (en) | 2007-01-17 |
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