EA200601123A1 - Фармацевтические композиции и способы лечения инсулином - Google Patents

Фармацевтические композиции и способы лечения инсулином

Info

Publication number
EA200601123A1
EA200601123A1 EA200601123A EA200601123A EA200601123A1 EA 200601123 A1 EA200601123 A1 EA 200601123A1 EA 200601123 A EA200601123 A EA 200601123A EA 200601123 A EA200601123 A EA 200601123A EA 200601123 A1 EA200601123 A1 EA 200601123A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
pharmaceutical compositions
treatment insulin
insulin
treatment
Prior art date
Application number
EA200601123A
Other languages
English (en)
Other versions
EA010885B1 (ru
Inventor
Роберт Дж. Гьюрик
Карл Реппуччи
Original Assignee
Бентли Фармасьютикалз Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бентли Фармасьютикалз Инк. filed Critical Бентли Фармасьютикалз Инк.
Publication of EA200601123A1 publication Critical patent/EA200601123A1/ru
Publication of EA010885B1 publication Critical patent/EA010885B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Раскрыты композиции и способы лечения пациента инсулином, которые включают в себя инсулин, усилитель проницаемости и носитель, который поддерживает кислое значение рН.
EA200601123A 2003-12-08 2004-12-02 Фармацевтические композиции и способы лечения инсулином EA010885B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52772803P 2003-12-08 2003-12-08
PCT/US2004/040313 WO2005056038A1 (en) 2003-12-08 2004-12-02 Pharmaceutical compositions and methods for insulin treatment

Publications (2)

Publication Number Publication Date
EA200601123A1 true EA200601123A1 (ru) 2006-10-27
EA010885B1 EA010885B1 (ru) 2008-12-30

Family

ID=34676771

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200601123A EA010885B1 (ru) 2003-12-08 2004-12-02 Фармацевтические композиции и способы лечения инсулином

Country Status (19)

Country Link
US (4) US7112561B2 (ru)
EP (2) EP2241326A1 (ru)
JP (2) JP2007513199A (ru)
KR (1) KR100978717B1 (ru)
CN (2) CN1913912B (ru)
AT (1) ATE474591T1 (ru)
AU (2) AU2004296784B2 (ru)
BR (1) BRPI0418589A (ru)
CA (1) CA2547990C (ru)
DE (1) DE602004028284D1 (ru)
DK (1) DK1706128T3 (ru)
EA (1) EA010885B1 (ru)
ES (1) ES2348303T3 (ru)
HK (1) HK1097464A1 (ru)
IL (1) IL176015A (ru)
NO (1) NO330737B1 (ru)
NZ (2) NZ547587A (ru)
WO (1) WO2005056038A1 (ru)
ZA (1) ZA200604683B (ru)

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US9925232B2 (en) 2013-07-23 2018-03-27 Serenity Pharmaceuticals, Llc Methods and compositions comprising desmopressin in combination with a 5-alpha reductase inhibitor
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CA2547990C (en) 2011-08-02
DE602004028284D1 (de) 2010-09-02
ZA200604683B (en) 2007-04-25
AU2010219399A1 (en) 2010-09-30
WO2005056038A1 (en) 2005-06-23
BRPI0418589A (pt) 2008-01-29
EP1706128B1 (en) 2010-07-21
US8044020B2 (en) 2011-10-25
CN1913912A (zh) 2007-02-14
EA010885B1 (ru) 2008-12-30
IL176015A0 (en) 2006-10-05
US20100144593A1 (en) 2010-06-10
JP2007513199A (ja) 2007-05-24
JP2009292820A (ja) 2009-12-17
KR100978717B1 (ko) 2010-08-30
NO20063135L (no) 2006-09-08
ES2348303T3 (es) 2010-12-02
US7112561B2 (en) 2006-09-26
AU2004296784A1 (en) 2005-06-23
US20050123592A1 (en) 2005-06-09
NO330737B1 (no) 2011-06-27
US7651996B2 (en) 2010-01-26
HK1097464A1 (en) 2007-06-29
US20090156464A1 (en) 2009-06-18
US20070010425A1 (en) 2007-01-11
CA2547990A1 (en) 2005-06-23
EP2241326A1 (en) 2010-10-20
NZ547587A (en) 2009-09-25
ATE474591T1 (de) 2010-08-15
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EP1706128A4 (en) 2008-11-26
CN1913912B (zh) 2010-06-16
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