EA200401600A1 - Новые комплексы карбоксипроизводных пиридина и эфиров жирной кислоты и полигидроксиалканов - Google Patents

Новые комплексы карбоксипроизводных пиридина и эфиров жирной кислоты и полигидроксиалканов

Info

Publication number
EA200401600A1
EA200401600A1 EA200401600A EA200401600A EA200401600A1 EA 200401600 A1 EA200401600 A1 EA 200401600A1 EA 200401600 A EA200401600 A EA 200401600A EA 200401600 A EA200401600 A EA 200401600A EA 200401600 A1 EA200401600 A1 EA 200401600A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pyridine
fatty acid
carboxy derivatives
polyhydroxialcanes
derivatives
Prior art date
Application number
EA200401600A
Other languages
English (en)
Other versions
EA008023B1 (ru
Inventor
Мортэн Слот Вэйднер
Original Assignee
Астион Дерматолоджи А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=30001772&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200401600(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Астион Дерматолоджи А/С filed Critical Астион Дерматолоджи А/С
Publication of EA200401600A1 publication Critical patent/EA200401600A1/ru
Publication of EA008023B1 publication Critical patent/EA008023B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)

Abstract

Данное изобретение касается новых комбинаций производных жирных кислот и карбоксипроизводных пиридина, включающих эфиры жирной кислоты и глицерина и 3-карбоксипроизводные пиридина, такие как ниацинамид. Такие комбинации проявляют удивительную антивирусную и антимикробную активность, и раскрыто их применение для лечения воспалительных состояний и инфекций.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200401600A 2002-06-20 2003-06-20 Новые комплексы карбоксипроизводных пиридина и эфиров жирной кислоты и полигидроксиалканов EA008023B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38987902P 2002-06-20 2002-06-20
DKPA200200951 2002-06-20
PCT/DK2003/000423 WO2004000333A1 (en) 2002-06-20 2003-06-20 Novel complexes of fatty acid esters of polyhydroxyalkanes and pyridine carboxy derivatives

Publications (2)

Publication Number Publication Date
EA200401600A1 true EA200401600A1 (ru) 2005-12-29
EA008023B1 EA008023B1 (ru) 2007-02-27

Family

ID=30001772

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200401600A EA008023B1 (ru) 2002-06-20 2003-06-20 Новые комплексы карбоксипроизводных пиридина и эфиров жирной кислоты и полигидроксиалканов

Country Status (20)

Country Link
US (2) US8084049B2 (ru)
EP (2) EP1640011A1 (ru)
JP (1) JP4589721B2 (ru)
KR (1) KR100983802B1 (ru)
CN (1) CN1674921A (ru)
AT (1) ATE341334T1 (ru)
AU (1) AU2003240441B2 (ru)
CA (1) CA2491871C (ru)
CY (1) CY1105902T1 (ru)
DE (1) DE60308891T2 (ru)
DK (1) DK1560589T3 (ru)
EA (1) EA008023B1 (ru)
ES (1) ES2274236T3 (ru)
HK (1) HK1076395A1 (ru)
NO (1) NO334647B1 (ru)
NZ (1) NZ537783A (ru)
PL (1) PL213646B1 (ru)
PT (1) PT1560589E (ru)
SI (1) SI1560589T1 (ru)
WO (1) WO2004000333A1 (ru)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6964297B1 (en) * 1998-07-14 2005-11-15 L & M Radiator, Inc. Removable tube heat exchanger and header plate
CA2531253A1 (en) 2003-07-02 2005-02-24 Vern L. Schramm Sir2 regulation
GB0425658D0 (en) 2004-11-22 2004-12-22 Stanford Rook Ltd Immunotherapeutic agent
US8858968B2 (en) 2005-12-05 2014-10-14 L'oreal Use of tyrosine-arginine dipeptide and niacinamide as substance P antagonist
FR2894142B1 (fr) * 2005-12-05 2009-06-12 Oreal Utilisation de l'association du dipeptide tyrosine-arginine et de la niacimanide en tant qu'antagoniste de substance p
EP1864657A1 (en) * 2006-06-08 2007-12-12 Astion Pharma A/S Treatment of cutaneous neurogenic inflammation
US8816110B2 (en) 2007-02-15 2014-08-26 Scf Pharma Inc. Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof
CA2672513C (en) * 2007-02-15 2010-05-25 Centre De Recherche Sur Les Biotechnologies Marines Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof
EP2136844B1 (en) 2007-03-20 2018-10-31 SCF Pharma Inc. Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof
JP2011526900A (ja) * 2008-06-30 2011-10-20 イーエルシー マネージメント エルエルシー イソニコチンアミドを含む外用組成物
JP2010126472A (ja) * 2008-11-27 2010-06-10 Marubeni Nisshin Feed Co Ltd クロストリジウム症の予防及び／又は治療用飼料
US20110097770A1 (en) * 2009-10-27 2011-04-28 Dr. Chifu Huang Novel method to generate bioactive compounds in algae
US20130052162A1 (en) * 2010-04-20 2013-02-28 Cedars-Sinai Medical Center Boosting immune defense by upregulating ccaat/enhancer binding protein epsilon
JP5726481B2 (ja) * 2010-10-29 2015-06-03 日本精化株式会社 ヒドロキシニコチン酸又はその誘導体を含有する化粧料又は皮膚外用剤
BR112013016220A2 (pt) 2010-12-23 2016-08-30 Hills Pet Nutrition Inc composições alimentares para animais domésticos e métodos para tratar artrite e inflamação associada com artrite
EP3062888A1 (en) 2013-10-28 2016-09-07 Cipher Pharmaceuticals Compositions for dermatological use
US9447020B2 (en) 2013-10-31 2016-09-20 Scf Pharma Inc. Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof
CN105061446B (zh) * 2015-07-17 2017-04-26 福建省肿瘤医院 源于桔青霉的penicitrinine A及在制备抗鼻咽癌药物上的应用
CN105001228B (zh) * 2015-07-17 2017-03-22 福建省肿瘤医院 源于桔青霉的penicitrinine A在制备抗人口腔表皮样瘤药物中的应用
CN105153176B (zh) * 2015-07-17 2017-06-06 福建省肿瘤医院 源于桔青霉的penicitrinine A及其制备抗人肺癌药物的应用
CN105061444B (zh) * 2015-07-17 2017-04-26 福建省肿瘤医院 源于桔青霉的penicitrinine A及其制备抗人结直肠癌药物的应用
CN105061445B (zh) * 2015-07-17 2017-04-26 福建省肿瘤医院 源于桔青霉的penicitrinine A及其制备抗人胃癌药物的应用
JP6880011B2 (ja) * 2015-10-05 2021-06-02 ユニリーバー・ナームローゼ・ベンノートシヤープ 皮膚美白組成物
CN106749211B (zh) * 2016-11-22 2019-08-09 斯芬克司药物研发（天津）股份有限公司 一种烟酸酯及其制备方法与应用
CN106854204B (zh) * 2016-11-22 2019-10-08 斯芬克司药物研发（天津）股份有限公司 一种烟酸脂化合物及其制备方法与应用
CN106749210B (zh) * 2016-11-22 2019-08-09 斯芬克司药物研发（天津）股份有限公司 一种烟酸酯类化合物及其制备方法与应用
EP3749297A4 (en) 2018-02-07 2021-04-14 SCF Pharma Inc. POLYUNSATURATED FATTY ACID MONOGLYCERIDES, CORRESPONDING COMPOSITIONS, METHODS AND USES
CN112384212A (zh) 2018-05-03 2021-02-19 Scf制药股份有限公司 多不饱和脂肪酸单甘油酯、其组合物、方法和用途
WO2021043719A1 (fr) * 2019-09-03 2021-03-11 Universite De Picardie Jules Verne Composition pharmaceutique antivirale contenant du thionicotinamide
CN113197897A (zh) * 2021-04-29 2021-08-03 四川大学 烟酰胺在制备变异链球菌产酸和生物膜形成抑制剂的应用

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3676556A (en) * 1969-09-26 1972-07-11 Hoffmann La Roche Method of stabilizing nialinamide against caking
US4002775A (en) * 1973-07-09 1977-01-11 Kabara Jon J Fatty acids and derivatives of antimicrobial agents
US5474783A (en) * 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5231087A (en) 1988-03-16 1993-07-27 Cellegy Pharmaceuticals, Inc. Treatment of skin diseases and tumors with esters and amides of monocarboxylic acids
JP2848830B2 (ja) * 1988-09-02 1999-01-20 旭電化工業株式会社 水に難溶性の脂肪酸エステルの可溶化方法
FI912955A (fi) 1990-06-25 1991-12-26 Res Found Mental Hygiene Antimikroba fettsyrasammansaettningar.
AU668559B2 (en) * 1992-06-03 1996-05-09 Unilever Plc Improvements relating to cosmetic compositions
DE4234188C2 (de) * 1992-10-10 1996-01-11 Beiersdorf Ag Antimycotische kosmetische und dermatologische Verwendungen
JPH06245719A (ja) * 1993-02-19 1994-09-06 Nippon Oil & Fats Co Ltd 粉末乳化剤および製造方法
DE4337711A1 (de) * 1993-11-05 1995-05-11 Beiersdorf Ag Gegen unreine Haut und milde Formen der Akne wirksame Zubereitungen mit einem Gehalt an Monocarbonsäuremonoglyceriden kurzer und mittellanger Fettsäuren
DE69501325T2 (de) * 1994-03-14 1998-09-03 Sloth Weidner Morten Methode zur solubilisierung organischer verbindungen in lipophilen systemen ,neue chemische komplexe solcher verbindungen und verschiedene anwendungen dieser komplexe
DE4434775A1 (de) * 1994-09-29 1996-04-04 Beiersdorf Ag Dermatologische Zubereitungen mit einem Gehalt an Fettsäureglyceriden gegen Superinfektionen
DE4434781A1 (de) * 1994-09-29 1996-04-04 Beiersdorf Ag Verwendung von Fettsäureestern zur Bekämpfung von Superinfektionen
DE4438588A1 (de) * 1994-10-28 1996-05-02 Beiersdorf Ag Gegen unreine Haut, leichte Formen der Akne sowie Propionibacterium acnes wirksame Wirkstoffkombinationen auf der Basis von Wollwachssäuren und Glycerinestern gesättigter Fettsäuren
WO1996034858A1 (en) * 1995-05-01 1996-11-07 Scotia Holdings Plc Nicotinic acid esters and pharmaceutical compositions containing them
JP3585306B2 (ja) * 1996-01-16 2004-11-04 エーザイ株式会社 防腐防黴剤
US6248763B1 (en) * 1998-05-19 2001-06-19 Scivoletto Rosemarie Composition for treating skin conditions
JP2003502435A (ja) * 1999-05-25 2003-01-21 ザ、プロクター、エンド、ギャンブル、カンパニー 軽減された粘着性を有するニコチン酸アミド組成物
JP3530075B2 (ja) * 1999-06-07 2004-05-24 三菱化学フーズ株式会社 乳化剤組成物
GB9916536D0 (en) * 1999-07-14 1999-09-15 Scarista Limited Nutritional or pharmaceutical compositions
JP2001078735A (ja) * 1999-09-09 2001-03-27 Yakult Honsha Co Ltd 乳化剤含有飲食品
JP2001128644A (ja) * 1999-11-05 2001-05-15 Takeda Chem Ind Ltd 固形状食品組成物
IL133976A (en) 2000-01-11 2006-09-05 Dermipsor Ltd Agents for the treatment of skin disorders
JP2003529590A (ja) 2000-03-21 2003-10-07 アスション デヴェロップメント エーピーエス ピリジンカルボキシ誘導体およびｈ２ヒスタミン受容体アンタゴニストからなる化学的複合体
WO2001074781A1 (en) 2000-03-21 2001-10-11 Astion Development Aps Chemical complex comprising a substituted pyridine carboxy derivative and a glucosaminoglycan
JP4921630B2 (ja) * 2000-05-10 2012-04-25 小川香料株式会社 ビタミン臭抑制剤
JP2003534361A (ja) * 2000-06-01 2003-11-18 ザ、プロクター、エンド、ギャンブル、カンパニー 油中水型乳化メークアップ組成物
CA2416512C (en) 2000-07-19 2010-10-19 Pitmy International N.V. Enhancement of the action of anti-infective agents
IL142536A0 (en) 2001-04-11 2002-03-10 Yeda Res & Dev Carriers for therapeutic preparations for treatment of t-cell mediated diseases

Also Published As

Publication number Publication date
JP2005537238A (ja) 2005-12-08
KR20050024356A (ko) 2005-03-10
PL375204A1 (en) 2005-11-28
PL213646B1 (pl) 2013-04-30
WO2004000333A1 (en) 2003-12-31
US8084049B2 (en) 2011-12-27
NZ537783A (en) 2006-12-22
DK1560589T3 (da) 2007-02-12
CN1674921A (zh) 2005-09-28
EP1560589A1 (en) 2005-08-10
CY1105902T1 (el) 2011-02-02
CA2491871A1 (en) 2003-12-31
HK1076395A1 (en) 2006-01-20
AU2003240441B2 (en) 2008-09-18
EP1640011A1 (en) 2006-03-29
US20060069131A1 (en) 2006-03-30
PT1560589E (pt) 2007-01-31
JP4589721B2 (ja) 2010-12-01
DE60308891T2 (de) 2007-05-24
AU2003240441A1 (en) 2004-01-06
EA008023B1 (ru) 2007-02-27
US20120142744A1 (en) 2012-06-07
ATE341334T1 (de) 2006-10-15
KR100983802B1 (ko) 2010-09-27
ES2274236T3 (es) 2007-05-16
EP1560589B1 (en) 2006-10-04
CA2491871C (en) 2011-01-04
SI1560589T1 (sl) 2007-02-28
DE60308891D1 (de) 2006-11-16
NO334647B1 (no) 2014-05-05
NO20050309L (no) 2005-03-18

Similar Documents

Publication Publication Date Title
EA200401600A1 (ru) Новые комплексы карбоксипроизводных пиридина и эфиров жирной кислоты и полигидроксиалканов
EA200401294A1 (ru) Производные хинолина и изохинолина, способ их получения и их применение в качестве ингибиторов воспаления
EA200400892A1 (ru) Производные никотинамида, полезные в качестве ингибиторов pde4
EA200401167A1 (ru) Производные тропана в качестве модуляторов ccr5
EA200401157A1 (ru) N-аминоацетилпирролидин-2-карбонитрилы и их применение в качестве ингибиторов ddp-iv
EA200800664A1 (ru) Производные пирролопиримидина в качестве ингибиторов syk
CO5700775A2 (es) Nuevos derivados triciclicos como antagonistas de ltd4
MY140841A (en) Indozolone derivatives as 11b-hsd1 inhibitors
EA201001455A1 (ru) Пиридины и пиразины в качестве ингибиторов pi3k (фосфатидилинозиткиназы-3)
ME01285A (me) Derivati dioksa-bicikl0[3.2.1]oktan-2,3,4-triola
DE60141895D1 (de) Substituierte beta-carboline mit ikb-kinase hemmender wirkung
CY1109925T1 (el) Η χρηση πυριδυλ αμιδιων ως παρεμποδιστων της αγγειογενεσης
PE20020058A1 (es) Derivados de piperidina tetrahidroquinolina, tetrahidroisoquinolina como inhibidores de caspasas
EA200300836A1 (ru) Производные фталазинон-пиперидина в качестве ингибиторов pde4
EA200401199A1 (ru) Ингибиторы гистондеацетилазы
EA199901026A1 (ru) Соединения и способы ингибирования экспрессии vcam-1
EA200400971A1 (ru) Фторзамещенные циклоалканоиндолы, композиции, содержащие такие соединения, и способы лечения
RS53617B1 (en) NEW UNITS USEFUL FOR TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES
DE602005008953D1 (de) Substituierte chinolinderivate als inhibitoren von mitotischem kinesin
ZA200709817B (en) 2,3 substituted pyrazine sulfonmides as inhibitors of CRTH2
CY1109992T1 (el) Παραγωγα του αλφα-αμιναμιδιου χρησιμα ως αντιφλεγμονωδη μεσα
DE60311869D1 (de) Kristalline cefdinirsalze
RS50781B (sr) Derivati pirido (2,3-d) pirimidina, njihovo dobijanje, njihova primena u terapiji
EA200300988A1 (ru) Производные фенил-гетероциклильных эфиров в качестве ингибиторов обратного захвата серотонина
EA200100852A1 (ru) Производные резорцина

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY RU

NF4A Restoration of lapsed right to a eurasian patent

Designated state(s): RU

PC4A Registration of transfer of a eurasian patent by assignment
PC4A Registration of transfer of a eurasian patent by assignment
TC4A Change in name of a patent proprietor in a eurasian patent
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY RU