EA200300338A1 - Способ контрацепции и формы введения контрацептивов - Google Patents

Способ контрацепции и формы введения контрацептивов

Info

Publication number
EA200300338A1
EA200300338A1 EA200300338A EA200300338A EA200300338A1 EA 200300338 A1 EA200300338 A1 EA 200300338A1 EA 200300338 A EA200300338 A EA 200300338A EA 200300338 A EA200300338 A EA 200300338A EA 200300338 A1 EA200300338 A1 EA 200300338A1
Authority
EA
Eurasian Patent Office
Prior art keywords
reception
administration
during
phase
phases
Prior art date
Application number
EA200300338A
Other languages
English (en)
Other versions
EA006875B1 (ru
Inventor
Херманн Кульманн
Original Assignee
Шеринг Акциенгезельшафт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Шеринг Акциенгезельшафт filed Critical Шеринг Акциенгезельшафт
Publication of EA200300338A1 publication Critical patent/EA200300338A1/ru
Publication of EA006875B1 publication Critical patent/EA006875B1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

В заявке описаны способ гормональной контрацепции, предусматривающий большое количество практически неограниченных по времени периодов, связанных с приемом средства, и необязательно повторяющихся в течение нескольких лет, которые в каждом случае включают, по меньшей мере, один цикл приема, имеющий в течение конкретного периода приема фазу приема постоянной продолжительности, составляющую несколько дней, и паузу в приеме, составляющую несколько дней, где в течение фазы или фаз приема осуществляют ежедневное введение суточной дозы, содержащей, по меньшей мере, один обладающий контрацептивной активностью гормональный компонент, такой как эстроген и/или гестаген, и в течение паузы или пауз в приеме вводят либо плацебо, в которых отсутствуют любые гормональные компоненты, либо в течение конкретной паузы в приеме введение полностью прекращают, и продолжительность фазы или фаз приема, по меньшей мере, в течение последнего периода приема составляет, по меньшей мере, 22 дня, отличающийся тем, что продолжительность фазы или фаз приема в любой предшествующий период приема является более короткой, чем в последующий период приема; а также форма введения, предназначенная для гормональной контрацепции и, прежде всего, для обеспечения ее эффективности.Отчет о международном поиске был опубликован 2002.07.04.
EA200300338A 2000-09-14 2001-09-05 Способ контрацепции и формы введения контрацептивов EA006875B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10045380A DE10045380A1 (de) 2000-09-14 2000-09-14 Verfahren zur Kontrazeption und dessen Darreichungsform
PCT/EP2001/010207 WO2002022110A2 (en) 2000-09-14 2001-09-05 Contraception process and administration form for the same

Publications (2)

Publication Number Publication Date
EA200300338A1 true EA200300338A1 (ru) 2003-08-28
EA006875B1 EA006875B1 (ru) 2006-04-28

Family

ID=7656125

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200300338A EA006875B1 (ru) 2000-09-14 2001-09-05 Способ контрацепции и формы введения контрацептивов

Country Status (32)

Country Link
US (2) US8076317B2 (ru)
EP (2) EP1317286B1 (ru)
JP (3) JP2004508398A (ru)
KR (3) KR20030031185A (ru)
CN (1) CN100560132C (ru)
AR (1) AR030737A1 (ru)
AT (1) ATE447972T1 (ru)
AU (2) AU8405201A (ru)
BG (2) BG107625A (ru)
BR (1) BR0113902A (ru)
CA (1) CA2420292C (ru)
CZ (1) CZ2003723A3 (ru)
DE (2) DE10045380A1 (ru)
EA (1) EA006875B1 (ru)
EE (1) EE200300103A (ru)
HK (1) HK1060305A1 (ru)
HR (1) HRP20030294A2 (ru)
HU (1) HUP0301042A3 (ru)
IL (2) IL154521A0 (ru)
ME (1) ME00291B (ru)
MX (1) MXPA03002070A (ru)
NO (1) NO20031152L (ru)
NZ (1) NZ524448A (ru)
PE (1) PE20020425A1 (ru)
PL (1) PL361161A1 (ru)
SK (1) SK3102003A3 (ru)
TW (1) TWI297271B (ru)
UA (1) UA93650C2 (ru)
UY (1) UY26932A1 (ru)
WO (1) WO2002022110A2 (ru)
YU (1) YU19003A (ru)
ZA (1) ZA200301359B (ru)

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Publication number Priority date Publication date Assignee Title
DE102004019743B4 (de) 2004-04-20 2008-11-27 Bayer Schering Pharma Aktiengesellschaft Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens
MY151322A (en) * 2004-04-30 2014-05-15 Bayer Ip Gmbh Management of breakthrough bleeding in extended hormonal contraceptive regimens
AU2011226911B2 (en) * 2004-04-30 2014-06-19 Bayer Intellectual Property Gmbh Management of breakthrough bleeding in extended hormonal contraceptive regimens
DE102004026670A1 (de) * 2004-05-28 2005-12-15 Grünenthal GmbH Hormonales Kontrazeptivum enthaltend eine Kombination aus Ethinylestradiol und Chlormadinonacetat
DE102004026669A1 (de) * 2004-05-28 2005-12-15 Grünenthal GmbH Verwendung einer Kombination aus Ethinylestradiol und Chlormadinonacetat zur Herstellung eines Arzneimittels
DE102004026679A1 (de) * 2004-05-28 2005-12-15 Grünenthal GmbH Hormonales Kontrazeptivum enthaltend eine Kombination aus Ethinylestradiol und Chlormadinonacetat
DE102004026671A1 (de) * 2004-05-28 2005-12-15 Grünenthal GmbH Darreichungsform zur hormonalen Kontrazeption
EP1655031A1 (de) 2004-10-08 2006-05-10 Schering AG Dienogest enthaltendes Langzeit-Verfahren zur Empfängnisverhütung
TW200727920A (en) * 2005-06-21 2007-08-01 Organon Nv New regimens for oral monophasic contraceptives
TW200744610A (en) * 2005-06-21 2007-12-16 Organon Nv New regimens for controlled drug delivery devices for contraception
US8153616B2 (en) 2005-10-17 2012-04-10 Bayer Pharma Aktiengesellschaft Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same
DE102006003509A1 (de) * 2006-01-24 2007-07-26 Grünenthal GmbH Kontrazeptivum
EP1930010A1 (de) 2006-10-20 2008-06-11 Bayer Schering Pharma Aktiengesellschaft Verwendung von Estradiolvalerat oder 17ß-Estradiol in Kombination mit Dienogest zur oralen Therapie für den Erhalt und/oder die Steigerung der weiblichen Libido
GB0623813D0 (en) * 2006-11-29 2007-01-10 Stephenson Group Ltd Foam reduction
DE102007011486A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Arzneimittel umfassend wenigstens ein Gestagen
EP2140860A1 (en) * 2008-07-03 2010-01-06 Bayer Schering Pharma Oy An improved method of contraception
LT2782584T (lt) 2011-11-23 2021-09-10 Therapeuticsmd, Inc. Natūralios kombinuotos pakaitinės hormonų terapijos kompozicijos ir gydymas
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
AU2015264003A1 (en) 2014-05-22 2016-11-17 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
DE2365103C3 (de) * 1973-12-21 1980-08-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen V erwendung von Hormonen zur Kontrazeption
NL9301562A (nl) * 1993-09-09 1995-04-03 Saturnus Ag Preparaat voor substitutietherapie.
DE4344462C2 (de) * 1993-12-22 1996-02-01 Schering Ag Zusammensetzung für die Empfängnisverhütung
ES2218556T3 (es) * 1994-11-22 2004-11-16 Balance Pharmaceuticals, Inc. Metodos de contracepcion.
DE19525017A1 (de) * 1995-06-28 1997-01-02 Schering Ag Pharmazeutisches Kombinatonspräparat, Kit und Methode zur hormonalen Kontrazeption
US5897539A (en) * 1995-09-28 1999-04-27 Schering Aktiengesellschaft Hormone replacement therapy method and hormone dispenser
ATE271386T1 (de) 1996-07-26 2004-08-15 Wyeth Corp Orale einstufige empfängnisverhütungsmethode und kombinationspräparat das gestagen und estrogen enthält
US5898032A (en) * 1997-06-23 1999-04-27 Medical College Of Hampton Roads Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy

Also Published As

Publication number Publication date
EP1317286B1 (en) 2009-11-11
YU19003A (sh) 2006-05-25
NO20031152D0 (no) 2003-03-13
BG111090A (bg) 2012-03-30
ME00291B (me) 2011-05-10
EP2153849A2 (en) 2010-02-17
HUP0301042A2 (hu) 2003-10-28
US20120129823A1 (en) 2012-05-24
HUP0301042A3 (en) 2010-03-29
KR20090033502A (ko) 2009-04-03
CA2420292A1 (en) 2002-03-21
KR20100056577A (ko) 2010-05-27
JP2013241456A (ja) 2013-12-05
US8536156B2 (en) 2013-09-17
AU8405201A (en) 2002-03-26
JP2013006866A (ja) 2013-01-10
TWI297271B (en) 2008-06-01
US20040219174A1 (en) 2004-11-04
CN100560132C (zh) 2009-11-18
JP2004508398A (ja) 2004-03-18
CA2420292C (en) 2010-12-14
AR030737A1 (es) 2003-09-03
IL154521A (en) 2014-05-28
BG107625A (bg) 2003-11-28
CN1455681A (zh) 2003-11-12
SK3102003A3 (en) 2003-09-11
UY26932A1 (es) 2001-12-28
HK1060305A1 (en) 2004-08-06
KR20030031185A (ko) 2003-04-18
MXPA03002070A (es) 2003-06-24
BR0113902A (pt) 2003-07-22
WO2002022110A3 (en) 2002-07-04
US8076317B2 (en) 2011-12-13
NO20031152L (no) 2003-05-14
EE200300103A (et) 2005-02-15
EP2153849A3 (en) 2011-09-14
ATE447972T1 (de) 2009-11-15
PL361161A1 (en) 2004-09-20
WO2002022110A2 (en) 2002-03-21
EA006875B1 (ru) 2006-04-28
NZ524448A (en) 2005-03-24
DE60140462D1 (de) 2009-12-24
IL154521A0 (en) 2003-09-17
HRP20030294A2 (en) 2005-02-28
PE20020425A1 (es) 2002-06-15
EP1317286A2 (en) 2003-06-11
CZ2003723A3 (cs) 2003-06-18
KR101240232B1 (ko) 2013-03-07
DE10045380A1 (de) 2002-04-04
UA93650C2 (ru) 2011-03-10
ZA200301359B (en) 2004-02-05
AU2001284052B2 (en) 2006-11-30
MEP37608A (en) 2011-02-10

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