EA200100187A1 - Фармацевтическая композиция для инъекций на основе парацетамола - Google Patents

Фармацевтическая композиция для инъекций на основе парацетамола

Info

Publication number
EA200100187A1
EA200100187A1 EA200100187A EA200100187A EA200100187A1 EA 200100187 A1 EA200100187 A1 EA 200100187A1 EA 200100187 A EA200100187 A EA 200100187A EA 200100187 A EA200100187 A EA 200100187A EA 200100187 A1 EA200100187 A1 EA 200100187A1
Authority
EA
Eurasian Patent Office
Prior art keywords
paracetamol
pharmaceutical composition
weight
injections based
injections
Prior art date
Application number
EA200100187A
Other languages
English (en)
Other versions
EA002648B1 (ru
Inventor
Джованни Кавалло
Марио Пинца
Original Assignee
Ацьенде Кимике Рьюните Анджелини Франческо А.К.Р.А.Ф. С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ацьенде Кимике Рьюните Анджелини Франческо А.К.Р.А.Ф. С.П.А. filed Critical Ацьенде Кимике Рьюните Анджелини Франческо А.К.Р.А.Ф. С.П.А.
Publication of EA200100187A1 publication Critical patent/EA200100187A1/ru
Publication of EA002648B1 publication Critical patent/EA002648B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Фармацевтическая композиция, отличающаяся тем, что a) она включает i) парацетамол, ii) от 1 до 4 об.ч. низкомолекулярного спирта на каждую вес.ч. парацетамола и iii) от 1 до 5 об.ч. полиэтиленгликоля на каждую вес.ч. парацетамола; b) она является, по существу, безводной; и c) она образует прозрачный раствор для инъекций с 4-10 об.ч. воды на каждую вес.ч. парацетамола.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200100187A 1998-07-31 1999-07-27 Фармацевтическая композиция для инъекций на основе парацетамола EA002648B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI001795A IT1301976B1 (it) 1998-07-31 1998-07-31 Composizione farmaceutica iniettabile a base di paracetamolo
PCT/EP1999/005486 WO2000007588A1 (en) 1998-07-31 1999-07-27 Pharmaceutical composition for injection based on paracetamol

Publications (2)

Publication Number Publication Date
EA200100187A1 true EA200100187A1 (ru) 2001-08-27
EA002648B1 EA002648B1 (ru) 2002-08-29

Family

ID=11380579

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200100187A EA002648B1 (ru) 1998-07-31 1999-07-27 Фармацевтическая композиция для инъекций на основе парацетамола

Country Status (25)

Country Link
US (1) US6423749B1 (ru)
EP (1) EP1094802B1 (ru)
JP (1) JP2002522384A (ru)
KR (1) KR20010071061A (ru)
CN (1) CN1146413C (ru)
AR (1) AR020638A1 (ru)
AT (1) ATE212225T1 (ru)
AU (1) AU754902B2 (ru)
BG (1) BG105274A (ru)
CA (1) CA2338728C (ru)
DE (1) DE69900823T2 (ru)
DK (1) DK1094802T3 (ru)
EA (1) EA002648B1 (ru)
ES (1) ES2170589T3 (ru)
GE (1) GEP20032986B (ru)
HK (1) HK1036011A1 (ru)
HU (1) HUP0102842A3 (ru)
IL (1) IL140920A0 (ru)
IT (1) IT1301976B1 (ru)
PL (1) PL196604B1 (ru)
PT (1) PT1094802E (ru)
SI (1) SI1094802T1 (ru)
SK (1) SK1222001A3 (ru)
TR (1) TR200100273T2 (ru)
WO (1) WO2000007588A1 (ru)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2796843B1 (fr) * 1999-07-29 2003-05-09 So Ge Val Sa Composition antipyretique concentree et stabilisee a usage veterinaire destine a etre incorporee a l'alimentation des animaux ainsi que procede d'incorporation de cette composition a l'eau de boisson d'animaux
ITMI20012135A1 (it) 2001-10-16 2003-04-16 Bioren S A Soluzioni iniettabili pronte all'uso di paracetamolo
FR2851164B1 (fr) * 2003-02-14 2005-04-22 Xuan Tho Nguyen Formulation liquide injectable de paracetamol
WO2005055148A1 (en) * 2003-11-29 2005-06-16 Vital Images, Inc. Segmented volume rendering using a programmable graphics pipeline
FR2862872A1 (fr) * 2003-12-02 2005-06-03 Palbian Snc Composition a l'etat aqueux pour l'application perfusable d'un principe actif, notamment pharmacologique tel que le paracetamol.
CA2628806C (en) 2006-07-18 2012-08-21 Genfarma Laboratorio S.L. Injectable liquid paracetamol formulation
ES2321906B1 (es) * 2008-11-28 2010-02-09 Laboratorios Normon, S.A. Composicion farmaceutica que comprende una solucion acuosa de paracetamol.
EP2243477A1 (de) * 2009-04-22 2010-10-27 Fresenius Kabi Deutschland GmbH Paracetamol zur parenteralen Verabreichung
EP2308463A1 (en) * 2009-10-12 2011-04-13 EMP Pharma GmbH Aqueous acetaminophen compositions and method of preparation
CN101816643B (zh) * 2009-12-31 2013-02-13 王石齐 含有双氯芬酸钠和对乙酰氨基酚的药物组合物
PT2377516E (pt) 2010-04-14 2012-07-02 Braun Melsungen Ag Composição acetaminofeno
CN102958519B (zh) * 2010-06-30 2016-01-13 特罗伊卡药品有限公司 包含扑热息痛的药物组合物及其制备方法
CN102258485A (zh) * 2011-01-11 2011-11-30 北京润德康医药技术有限公司 一种含对乙酰氨基酚的注射用制剂及其应用
US20150141518A1 (en) * 2013-11-21 2015-05-21 Emphascience, Inc. Water-miscible stable solution composition for pharmaceutically active ingredients that are poorly soluble in water and susceptible to chemical degradation
US20160144033A1 (en) * 2014-11-21 2016-05-26 Emphascience, Inc. Concentrated acetaminophen solution
SG11201704435PA (en) * 2014-12-20 2017-06-29 Troikaa Pharmaceuticals Ltd Injectable formulations of paracetamol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307073A (en) 1980-08-08 1981-12-22 The Research Foundation Of State University Of New York Method and composition for reducing the toxicity of acetaminophen
DD279405A1 (de) 1989-01-10 1990-06-06 Berlin Chemie Veb Verfahren zur herstellung eines parenteral applizierbaren analgetikums/antipyretikums
KR930011994B1 (ko) 1991-08-16 1993-12-23 대광제약 주식회사 파라세타몰의 생체이용율을 높이는 방법 및 이 생체이용율이 높아진 파라세타몰을 함유한 제제
FR2751875B1 (fr) 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation

Also Published As

Publication number Publication date
PL345767A1 (en) 2002-01-02
ITMI981795A0 (it) 1998-07-31
GEP20032986B (en) 2003-06-25
AR020638A1 (es) 2002-05-22
HUP0102842A3 (en) 2003-12-29
HUP0102842A2 (hu) 2002-05-29
ITMI981795A1 (it) 2000-01-31
JP2002522384A (ja) 2002-07-23
EP1094802A1 (en) 2001-05-02
US6423749B1 (en) 2002-07-23
IL140920A0 (en) 2002-02-10
DE69900823D1 (de) 2002-03-14
AU5729499A (en) 2000-02-28
WO2000007588A1 (en) 2000-02-17
CN1146413C (zh) 2004-04-21
CN1311672A (zh) 2001-09-05
HK1036011A1 (en) 2001-12-21
AU754902B2 (en) 2002-11-28
ATE212225T1 (de) 2002-02-15
PT1094802E (pt) 2002-07-31
SK1222001A3 (en) 2001-09-11
SI1094802T1 (en) 2002-08-31
KR20010071061A (ko) 2001-07-28
EP1094802B1 (en) 2002-01-23
PL196604B1 (pl) 2008-01-31
BG105274A (en) 2001-11-30
IT1301976B1 (it) 2000-07-20
EA002648B1 (ru) 2002-08-29
ES2170589T3 (es) 2002-08-01
DE69900823T2 (de) 2002-08-29
CA2338728A1 (en) 2000-02-17
DK1094802T3 (da) 2002-05-06
CA2338728C (en) 2008-01-22
TR200100273T2 (tr) 2001-05-21

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU