EA199700310A1 - Биологический способ получения соединений дипептидной природы - Google Patents
Биологический способ получения соединений дипептидной природыInfo
- Publication number
- EA199700310A1 EA199700310A1 EA199700310A EA199700310A EA199700310A1 EA 199700310 A1 EA199700310 A1 EA 199700310A1 EA 199700310 A EA199700310 A EA 199700310A EA 199700310 A EA199700310 A EA 199700310A EA 199700310 A1 EA199700310 A1 EA 199700310A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- dipeptid
- nature
- biological method
- obtaining compounds
- dipeptide intermediate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/463—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from amphibians
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Botany (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Раскрывается биологический способ получения соединений, которые могут быть получены из дипептидного интермедиата. Указанный способ включает продуцирование рекомбинантного полипептида, который содержит дипептидный интермедиат. Дипептидный интермедиат далее подвергают процессингу с получением готового продукта.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41978795A | 1995-04-11 | 1995-04-11 | |
PCT/US1996/004794 WO1996032468A2 (en) | 1995-04-11 | 1996-04-08 | Bioprocess for production of dipeptide based compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
EA199700310A1 true EA199700310A1 (ru) | 1998-04-30 |
EA000736B1 EA000736B1 (ru) | 2000-02-28 |
Family
ID=23663762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA199700310A EA000736B1 (ru) | 1995-04-11 | 1996-04-08 | Способ получения дипептидов |
Country Status (13)
Country | Link |
---|---|
US (1) | US6204008B1 (ru) |
EP (1) | EP0820465B1 (ru) |
CN (1) | CN1193998A (ru) |
AR (1) | AR001594A1 (ru) |
AT (1) | ATE247129T1 (ru) |
AU (1) | AU5445596A (ru) |
BR (1) | BR9608278A (ru) |
CZ (1) | CZ321497A3 (ru) |
DE (1) | DE69629460T2 (ru) |
EA (1) | EA000736B1 (ru) |
ES (1) | ES2203690T3 (ru) |
SK (1) | SK138197A3 (ru) |
WO (1) | WO1996032468A2 (ru) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006521724A (ja) * | 2003-01-28 | 2006-09-21 | セルポート システムズ インコーポレイテッド | セキュア・テレマティクス |
CN100420746C (zh) * | 2005-06-24 | 2008-09-24 | 北京化工大学 | 重组降压肽的设计与发酵生产 |
GB0608368D0 (en) * | 2006-04-28 | 2006-06-07 | Isis Innovation | Process for making Oligopeptides |
JP6628285B2 (ja) * | 2013-03-14 | 2020-01-08 | ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド | Als関連ジアミノ酸リピート含有タンパク質 |
WO2016196324A1 (en) | 2015-05-29 | 2016-12-08 | University Of Floridia Research Foundation, Inc. | Methods for diagnosing huntington's disease |
US10940161B2 (en) | 2016-04-04 | 2021-03-09 | University Of Florida Research Foundation, Incorporated | Manipulation of EIF3 to modulate repeat associated non-ATG (RAN) translation |
EP3612190A4 (en) | 2017-04-17 | 2021-01-20 | University of Florida Research Foundation, Incorporated | REGULATION OF RAN TRANSLATION THROUGH PKR AND EIF2A-P WAYS |
CA3076214A1 (en) | 2017-09-26 | 2019-04-04 | University Of Florida Research Foundation, Incorporated | Use of metformin and analogs thereof to reduce ran protein levels in the treatment of neurological disorders |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL58849A (en) | 1978-12-11 | 1983-03-31 | Merck & Co Inc | Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them |
GB2068971B (en) * | 1980-01-30 | 1983-06-08 | Searle & Co | Recombinant dna techniques |
EP0036258A3 (en) * | 1980-03-14 | 1982-02-10 | Cetus Corporation | Process for producing aspartame |
US4555502A (en) | 1982-09-30 | 1985-11-26 | Merck & Co., Inc. | Aminoacyl-containing dipeptide derivatives useful as antihypertensives |
DD248961A1 (de) * | 1984-05-22 | 1987-08-26 | Akad Wissenschaften Ddr | Verfahren zur herstellung wundheilungsfoerdernder praeparationen |
US5089406A (en) | 1987-01-07 | 1992-02-18 | Allied-Signal Inc. | Method of producing a gene cassette coding for polypeptides with repeating amino acid sequences |
NL8700767A (nl) | 1987-04-01 | 1988-11-01 | Groningen Science Park | Dipeptidase, isolering daarvan uit melkzuurbacterien, antilichamen tegen het dipeptidase, gebruik van het dipeptidase en van de antilichamen daartegen. |
JPH07108232B2 (ja) * | 1990-10-09 | 1995-11-22 | エム・ディ・リサーチ株式会社 | ペプチド又は蛋白質の製造方法 |
PT524906E (pt) * | 1991-07-24 | 2003-08-29 | Novartis Ag | Dna codificador de prolilendopeptidase |
ATE253639T1 (de) | 1991-08-19 | 2003-11-15 | Daiichi Suntory Pharma Co Ltd | Verfahren zur herstellung von peptiden |
WO1994016082A1 (en) * | 1992-12-30 | 1994-07-21 | Communaute Economique Europeenne (Cee) | X-prolyl-dipeptidyl-aminopeptidase from lactobacillus delbrückii ssp. lactis, nucleic acids coding for the same and its use in fermented foodstuff preparation processes |
-
1996
- 1996-04-08 CZ CZ973214A patent/CZ321497A3/cs unknown
- 1996-04-08 AU AU54455/96A patent/AU5445596A/en not_active Abandoned
- 1996-04-08 CN CN96194302A patent/CN1193998A/zh active Pending
- 1996-04-08 ES ES96911630T patent/ES2203690T3/es not_active Expired - Lifetime
- 1996-04-08 WO PCT/US1996/004794 patent/WO1996032468A2/en active IP Right Grant
- 1996-04-08 BR BR9608278-0A patent/BR9608278A/pt not_active Application Discontinuation
- 1996-04-08 AT AT96911630T patent/ATE247129T1/de not_active IP Right Cessation
- 1996-04-08 EP EP96911630A patent/EP0820465B1/en not_active Expired - Lifetime
- 1996-04-08 SK SK1381-97A patent/SK138197A3/sk unknown
- 1996-04-08 EA EA199700310A patent/EA000736B1/ru not_active IP Right Cessation
- 1996-04-08 DE DE69629460T patent/DE69629460T2/de not_active Expired - Fee Related
- 1996-04-10 AR AR33611996A patent/AR001594A1/es unknown
- 1996-11-12 US US08/748,073 patent/US6204008B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69629460D1 (de) | 2003-09-18 |
ATE247129T1 (de) | 2003-08-15 |
ES2203690T3 (es) | 2004-04-16 |
WO1996032468A2 (en) | 1996-10-17 |
BR9608278A (pt) | 1999-10-13 |
CN1193998A (zh) | 1998-09-23 |
EA000736B1 (ru) | 2000-02-28 |
WO1996032468A3 (en) | 1996-11-28 |
SK138197A3 (en) | 1998-07-08 |
DE69629460T2 (de) | 2004-06-24 |
EP0820465A2 (en) | 1998-01-28 |
EP0820465B1 (en) | 2003-08-13 |
US6204008B1 (en) | 2001-03-20 |
AR001594A1 (es) | 1997-11-26 |
AU5445596A (en) | 1996-10-30 |
CZ321497A3 (cs) | 1998-06-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM |
|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): RU |