EA038531B1 - Способ лечения амиотрофного латерального склероза, применение фармацевтической композиции, содержащей мазитиниб - Google Patents
Способ лечения амиотрофного латерального склероза, применение фармацевтической композиции, содержащей мазитиниб Download PDFInfo
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- EA038531B1 EA038531B1 EA201800499A EA201800499A EA038531B1 EA 038531 B1 EA038531 B1 EA 038531B1 EA 201800499 A EA201800499 A EA 201800499A EA 201800499 A EA201800499 A EA 201800499A EA 038531 B1 EA038531 B1 EA 038531B1
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16162490 | 2016-03-25 | ||
| PCT/EP2017/057134 WO2017162884A1 (en) | 2016-03-25 | 2017-03-24 | Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201800499A1 EA201800499A1 (ru) | 2019-03-29 |
| EA038531B1 true EA038531B1 (ru) | 2021-09-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201800499A EA038531B1 (ru) | 2016-03-25 | 2017-03-24 | Способ лечения амиотрофного латерального склероза, применение фармацевтической композиции, содержащей мазитиниб |
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| JP (2) | JP7250312B2 (enExample) |
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| CA (1) | CA3018635C (enExample) |
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| PT (1) | PT3240538T (enExample) |
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| US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| CN104869993B (zh) | 2012-10-25 | 2019-01-15 | 通用医疗公司 | 治疗阿尔茨海默病及相关疾病的组合疗法 |
| US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
| AU2014340182B2 (en) | 2013-10-22 | 2019-05-23 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| US20190240194A1 (en) * | 2016-08-31 | 2019-08-08 | The General Hospital Corporation | Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases |
| MX379222B (es) | 2016-11-25 | 2025-03-10 | Genuv Inc | Composición para promover la diferenciación y protección de células madre neurales y método para inducir la regeneración neural usando las mismas. |
| CA3057040A1 (en) * | 2017-03-28 | 2018-10-04 | Novartis Ag | New methods for the treatment of multiple sclerosis |
| BR112019025346A2 (pt) * | 2017-05-30 | 2020-06-30 | Deciphera Pharmaceuticals, Inc. | uso de 1-[4-bromo-5-[1-etil-7-(metilamino)-2-oxo-1,2-dihidro-1,6-naftiridin-3-il]-2-fluorofenil]-3-fenilureia e análogos para o tratamento de cânceres associados a anormalidades genéticas no receptor alfa do fator de crescimento derivado de plaquetas |
| US11692029B2 (en) | 2018-03-05 | 2023-07-04 | The Schepens Eye Research Institute, Inc. | Therapy for glaucoma and optic neuropathy by targeting colony stimulating factors |
| KR20210071943A (ko) | 2018-07-02 | 2021-06-16 | 더 제너럴 하스피탈 코포레이션 | 크로몰린 소듐 및 α-락토스의 분말화된 제형 |
| US12383528B2 (en) | 2018-12-10 | 2025-08-12 | The General Hospital Corporation | Cromolyn esters and uses thereof |
| CN112618717A (zh) * | 2019-09-24 | 2021-04-09 | 北京大学深圳研究生院 | Btk抑制剂用于治疗肌萎缩侧索硬化症的用途 |
| FI4084779T3 (fi) * | 2019-12-30 | 2024-12-16 | Deciphera Pharmaceuticals Llc | 1-(4-bromi-5-(1-etyyli-7-(metyyliamino)-2-okso-1,2-dihydro-1,6-naftyridin-3-yyli)-2-fluorifenyyli)-3-fenyyliurean koostumuksia |
| WO2021207060A1 (en) | 2020-04-06 | 2021-10-14 | The General Hospital Corporation | Methods of treatment of coronavirus-induced inflammation conditions |
| US12612391B2 (en) | 2020-12-28 | 2026-04-28 | The General Hospital Corporation | Cromolyn derivatives and uses thereof |
| US20250129067A1 (en) * | 2021-11-08 | 2025-04-24 | Progentos Therapeutics, Inc. | Platelet-derived growth factor receptor (pdgfr) alpha inhibitors and uses thereof |
| WO2025113494A1 (zh) * | 2023-11-27 | 2025-06-05 | 浙江径科医药有限公司 | 多环类化合物及其应用 |
| WO2026015576A1 (en) * | 2024-07-09 | 2026-01-15 | PhenoNet, Inc. | Methods and systems for treatment of neurodegenerative disease and uses thereof |
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| WO2015063318A1 (en) * | 2013-11-04 | 2015-05-07 | Ab Science | Use of masitinib for treatment of amyotrophic lateral sclerosis |
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| HRP20110709T1 (hr) | 2007-02-13 | 2011-11-30 | Ab Science | Postupak sinteze spojeva 2-aminotioazola kao inhibitora kinaza |
| TW201204360A (en) | 2010-04-20 | 2012-02-01 | Ab Science | Treatment of multiple sclerosis with MASITINIB |
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| AU2013326463B2 (en) * | 2012-10-04 | 2018-01-18 | Ab Science | Use of masitinib for treatment of cancer in patient subpopulations identified using predictor factors |
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| EA201800499A1 (ru) | 2019-03-29 |
| CN108883108A (zh) | 2018-11-23 |
| KR20180125966A (ko) | 2018-11-26 |
| PT3240538T (pt) | 2021-12-07 |
| EP3240538B1 (en) | 2021-09-29 |
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| BR112018069515A2 (pt) | 2019-04-16 |
| SI3240538T1 (sl) | 2022-02-28 |
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| HUE057398T2 (hu) | 2022-05-28 |
| KR102293847B1 (ko) | 2021-08-26 |
| AU2017236177B2 (en) | 2022-03-31 |
| JP2022037132A (ja) | 2022-03-08 |
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