PT3240538T - Uso de masitinib para tratamento de uma subpopulação de pacientes com esclerose lateral amiotrófica - Google Patents

Uso de masitinib para tratamento de uma subpopulação de pacientes com esclerose lateral amiotrófica

Info

Publication number
PT3240538T
PT3240538T PT177121753T PT17712175T PT3240538T PT 3240538 T PT3240538 T PT 3240538T PT 177121753 T PT177121753 T PT 177121753T PT 17712175 T PT17712175 T PT 17712175T PT 3240538 T PT3240538 T PT 3240538T
Authority
PT
Portugal
Prior art keywords
masitinib
treatment
lateral sclerosis
amyotrophic lateral
patient subpopulation
Prior art date
Application number
PT177121753T
Other languages
English (en)
Original Assignee
Ab Science
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ab Science filed Critical Ab Science
Publication of PT3240538T publication Critical patent/PT3240538T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/428Thiazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT177121753T 2016-03-25 2017-03-24 Uso de masitinib para tratamento de uma subpopulação de pacientes com esclerose lateral amiotrófica PT3240538T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16162490 2016-03-25

Publications (1)

Publication Number Publication Date
PT3240538T true PT3240538T (pt) 2021-12-07

Family

ID=55637258

Family Applications (1)

Application Number Title Priority Date Filing Date
PT177121753T PT3240538T (pt) 2016-03-25 2017-03-24 Uso de masitinib para tratamento de uma subpopulação de pacientes com esclerose lateral amiotrófica

Country Status (20)

Country Link
US (1) US10092564B2 (pt)
EP (1) EP3240538B1 (pt)
JP (2) JP7250312B2 (pt)
KR (1) KR102293847B1 (pt)
CN (1) CN108883108B (pt)
AU (1) AU2017236177B2 (pt)
BR (1) BR112018069515A2 (pt)
CA (1) CA3018635C (pt)
DK (1) DK3240538T3 (pt)
EA (1) EA038531B1 (pt)
ES (1) ES2899929T3 (pt)
HU (1) HUE057398T2 (pt)
IL (1) IL261856B (pt)
MX (1) MX2018011349A (pt)
NZ (1) NZ745778A (pt)
PL (1) PL3240538T3 (pt)
PT (1) PT3240538T (pt)
SG (1) SG11201808106YA (pt)
SI (1) SI3240538T1 (pt)
WO (1) WO2017162884A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9925282B2 (en) 2009-01-29 2018-03-27 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
CN104869993B (zh) 2012-10-25 2019-01-15 通用医疗公司 治疗阿尔茨海默病及相关疾病的组合疗法
US10525005B2 (en) 2013-05-23 2020-01-07 The General Hospital Corporation Cromolyn compositions and methods thereof
US10188757B2 (en) 2013-10-22 2019-01-29 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
EP3506894B1 (en) * 2016-08-31 2023-08-23 The General Hospital Corporation Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases
DK3425390T3 (da) 2016-11-25 2021-02-15 Genuv Inc Sammensætning til fremme af differentiering og beskyttelse af neurale stamceller og fremgangsmåde til induktion af neural regenerering ved anvendelse heraf
CN110475555A (zh) * 2017-03-28 2019-11-19 诺华股份有限公司 治疗多发性硬化的新方法
CN111328283A (zh) * 2017-05-30 2020-06-23 德西费拉制药有限责任公司 1-[4-溴-5-[1-乙基-7-(甲氨基)-2-氧代-1,2-二氢-1,6-萘啶-3-基]-2-氟苯基]-3-苯基脲和类似物用于治疗与血小板衍生的生长因子受体α中的遗传异常相关的癌症的用途
WO2019173361A2 (en) 2018-03-05 2019-09-12 The Schepens Eye Research Institute, Inc. A therapy for glaucoma and optic neuropathy by targeting colony stimulating factors
AU2019299347A1 (en) 2018-07-02 2021-01-21 Aztherapies, Inc. Powdered formulations of cromolyn sodium and alpha-lactose
CN112618717A (zh) * 2019-09-24 2021-04-09 北京大学深圳研究生院 Btk抑制剂用于治疗肌萎缩侧索硬化症的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW225528B (pt) 1992-04-03 1994-06-21 Ciba Geigy Ag
CO4940418A1 (es) 1997-07-18 2000-07-24 Novartis Ag Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
CN100491374C (zh) 2002-08-02 2009-05-27 Ab科学公司 2-(3-氨基芳基)氨基-4-芳基-噻唑及其作为c-kit抑制剂的应用
US8450302B2 (en) 2002-08-02 2013-05-28 Ab Science 2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors
US8153792B2 (en) 2007-02-13 2012-04-10 Ab Science Process for the synthesis of 2-aminothiazole compounds as kinase inhibitors
US8906357B2 (en) 2010-04-20 2014-12-09 Ab Science Treatment of multiple sclerosis with masitinib
IN2014DN00200A (pt) 2011-07-13 2015-06-05 Cytokinetics Inc
EP2903616B8 (en) * 2012-10-04 2018-02-07 AB Science Use of masitinib in combination with gemcitabine for treating a subgroup of patients suffering from pancreatic cancer
US9676792B2 (en) * 2013-03-15 2017-06-13 Dana-Farber Cancer Institute, Inc. Pyrimido-diazepinone compounds and methods of treating disorders
WO2015063318A1 (en) * 2013-11-04 2015-05-07 Ab Science Use of masitinib for treatment of amyotrophic lateral sclerosis

Also Published As

Publication number Publication date
PL3240538T3 (pl) 2022-01-31
DK3240538T3 (da) 2021-12-06
SI3240538T1 (sl) 2022-02-28
US10092564B2 (en) 2018-10-09
MX2018011349A (es) 2019-02-07
HUE057398T2 (hu) 2022-05-28
BR112018069515A2 (pt) 2019-04-16
AU2017236177B2 (en) 2022-03-31
WO2017162884A1 (en) 2017-09-28
SG11201808106YA (en) 2018-10-30
IL261856B (en) 2022-04-01
JP2019515884A (ja) 2019-06-13
KR20180125966A (ko) 2018-11-26
ES2899929T3 (es) 2022-03-15
JP7250312B2 (ja) 2023-04-03
CA3018635A1 (en) 2017-09-28
AU2017236177A1 (en) 2018-09-20
CN108883108B (zh) 2021-08-06
JP2022037132A (ja) 2022-03-08
CN108883108A (zh) 2018-11-23
EA201800499A1 (ru) 2019-03-29
EA038531B1 (ru) 2021-09-10
CA3018635C (en) 2023-09-26
KR102293847B1 (ko) 2021-08-26
EP3240538A1 (en) 2017-11-08
NZ745778A (en) 2022-07-01
EP3240538B1 (en) 2021-09-29
US20180117037A1 (en) 2018-05-03
IL261856A (en) 2018-10-31

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