DK3240538T3 - Anvendelse af masitinib til behandling af en underpopulation af patienter med amyotrofisk lateralsklerose - Google Patents
Anvendelse af masitinib til behandling af en underpopulation af patienter med amyotrofisk lateralsklerose Download PDFInfo
- Publication number
- DK3240538T3 DK3240538T3 DK17712175.3T DK17712175T DK3240538T3 DK 3240538 T3 DK3240538 T3 DK 3240538T3 DK 17712175 T DK17712175 T DK 17712175T DK 3240538 T3 DK3240538 T3 DK 3240538T3
- Authority
- DK
- Denmark
- Prior art keywords
- unpopulation
- masitinib
- patients
- treatment
- lateral sclerosis
- Prior art date
Links
- 239000002139 L01XE22 - Masitinib Substances 0.000 title 1
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 title 1
- WJEOLQLKVOPQFV-UHFFFAOYSA-N masitinib Chemical compound C1CN(C)CCN1CC1=CC=C(C(=O)NC=2C=C(NC=3SC=C(N=3)C=3C=NC=CC=3)C(C)=CC=2)C=C1 WJEOLQLKVOPQFV-UHFFFAOYSA-N 0.000 title 1
- 229960004655 masitinib Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16162490 | 2016-03-25 | ||
| PCT/EP2017/057134 WO2017162884A1 (en) | 2016-03-25 | 2017-03-24 | Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3240538T3 true DK3240538T3 (da) | 2021-12-06 |
Family
ID=55637258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17712175.3T DK3240538T3 (da) | 2016-03-25 | 2017-03-24 | Anvendelse af masitinib til behandling af en underpopulation af patienter med amyotrofisk lateralsklerose |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US10092564B2 (da) |
| EP (1) | EP3240538B1 (da) |
| JP (2) | JP7250312B2 (da) |
| KR (1) | KR102293847B1 (da) |
| CN (1) | CN108883108B (da) |
| AU (1) | AU2017236177B2 (da) |
| BR (1) | BR112018069515A2 (da) |
| CA (1) | CA3018635C (da) |
| DK (1) | DK3240538T3 (da) |
| EA (1) | EA038531B1 (da) |
| ES (1) | ES2899929T3 (da) |
| HU (1) | HUE057398T2 (da) |
| IL (1) | IL261856B (da) |
| MX (1) | MX2018011349A (da) |
| NZ (1) | NZ745778A (da) |
| PL (1) | PL3240538T3 (da) |
| PT (1) | PT3240538T (da) |
| SG (1) | SG11201808106YA (da) |
| SI (1) | SI3240538T1 (da) |
| WO (1) | WO2017162884A1 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| EP3563849A3 (en) | 2012-10-25 | 2020-02-12 | The General Hospital Corporation | Combination therapies for the treatment of alzheimer's disease and related disorders |
| US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
| CA2928028A1 (en) | 2013-10-22 | 2015-04-30 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| CN116889562A (zh) | 2016-08-31 | 2023-10-17 | 通用医疗公司 | 与神经退行性疾病相关的神经炎症中的巨噬细胞/小胶质细胞 |
| CN115025225A (zh) | 2016-11-25 | 2022-09-09 | 基诺富公司 | 用于诱导神经干细胞的分化和保护的组合物及使用该组合物诱导神经再生的方法 |
| CA3057040A1 (en) * | 2017-03-28 | 2018-10-04 | Novartis Ag | New methods for the treatment of multiple sclerosis |
| US20200129489A1 (en) * | 2017-05-30 | 2020-04-30 | Deciphera Pharmaceuticals, Llc | Use of 1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea and analogs for the treatment of cancers associated with genetic abnormalities in platelet derived growth factor receptor alpha |
| JP7463281B2 (ja) * | 2018-03-05 | 2024-04-08 | ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド | コロニー刺激因子を標的とすることによる、緑内障および視神経症のための療法 |
| AU2019299347A1 (en) | 2018-07-02 | 2021-01-21 | Aztherapies, Inc. | Powdered formulations of cromolyn sodium and alpha-lactose |
| CN112618717A (zh) * | 2019-09-24 | 2021-04-09 | 北京大学深圳研究生院 | Btk抑制剂用于治疗肌萎缩侧索硬化症的用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW225528B (da) | 1992-04-03 | 1994-06-21 | Ciba Geigy Ag | |
| CO4940418A1 (es) | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
| CN100491374C (zh) | 2002-08-02 | 2009-05-27 | Ab科学公司 | 2-(3-氨基芳基)氨基-4-芳基-噻唑及其作为c-kit抑制剂的应用 |
| US8450302B2 (en) | 2002-08-02 | 2013-05-28 | Ab Science | 2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors |
| US8153792B2 (en) | 2007-02-13 | 2012-04-10 | Ab Science | Process for the synthesis of 2-aminothiazole compounds as kinase inhibitors |
| WO2011131705A1 (en) | 2010-04-20 | 2011-10-27 | Ab Science | Treatment of multiple sclerosis with masitinib |
| CA2849213A1 (en) | 2011-07-13 | 2013-01-17 | Cytokinetics, Inc. | Combination of riluzole and ck-2017357 for treating als |
| SI2903616T1 (en) * | 2012-10-04 | 2018-02-28 | Ab Science | The use of masitinib in combination with gemcitabine for the treatment of a subgroup of patients suffering from foot-and-mouth disease |
| EP3738964A1 (en) * | 2013-03-15 | 2020-11-18 | Dana Farber Cancer Institute, Inc. | Pyrimido-diazepinone compounds and methods of treating disorders |
| US20160263110A1 (en) * | 2013-11-04 | 2016-09-15 | Ab Science | Use of masitinib for treatment of amyotrophic lateral sclerosis |
-
2017
- 2017-03-24 JP JP2018549902A patent/JP7250312B2/ja active Active
- 2017-03-24 WO PCT/EP2017/057134 patent/WO2017162884A1/en active Application Filing
- 2017-03-24 EP EP17712175.3A patent/EP3240538B1/en active Active
- 2017-03-24 ES ES17712175T patent/ES2899929T3/es active Active
- 2017-03-24 PL PL17712175T patent/PL3240538T3/pl unknown
- 2017-03-24 DK DK17712175.3T patent/DK3240538T3/da active
- 2017-03-24 KR KR1020187026871A patent/KR102293847B1/ko active IP Right Grant
- 2017-03-24 MX MX2018011349A patent/MX2018011349A/es unknown
- 2017-03-24 EA EA201800499A patent/EA038531B1/ru unknown
- 2017-03-24 PT PT177121753T patent/PT3240538T/pt unknown
- 2017-03-24 SI SI201730997T patent/SI3240538T1/sl unknown
- 2017-03-24 CA CA3018635A patent/CA3018635C/en active Active
- 2017-03-24 BR BR112018069515A patent/BR112018069515A2/pt not_active Application Discontinuation
- 2017-03-24 NZ NZ745778A patent/NZ745778A/en unknown
- 2017-03-24 AU AU2017236177A patent/AU2017236177B2/en active Active
- 2017-03-24 SG SG11201808106YA patent/SG11201808106YA/en unknown
- 2017-03-24 CN CN201780019760.9A patent/CN108883108B/zh active Active
- 2017-03-24 HU HUE17712175A patent/HUE057398T2/hu unknown
- 2017-03-24 US US15/545,800 patent/US10092564B2/en active Active
-
2018
- 2018-09-20 IL IL261856A patent/IL261856B/en unknown
-
2021
- 2021-12-16 JP JP2021204244A patent/JP2022037132A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20180117037A1 (en) | 2018-05-03 |
| CN108883108B (zh) | 2021-08-06 |
| CN108883108A (zh) | 2018-11-23 |
| MX2018011349A (es) | 2019-02-07 |
| BR112018069515A2 (pt) | 2019-04-16 |
| KR102293847B1 (ko) | 2021-08-26 |
| EA038531B1 (ru) | 2021-09-10 |
| AU2017236177A1 (en) | 2018-09-20 |
| AU2017236177B2 (en) | 2022-03-31 |
| HUE057398T2 (hu) | 2022-05-28 |
| NZ745778A (en) | 2022-07-01 |
| EP3240538B1 (en) | 2021-09-29 |
| EA201800499A1 (ru) | 2019-03-29 |
| PL3240538T3 (pl) | 2022-01-31 |
| IL261856A (en) | 2018-10-31 |
| SG11201808106YA (en) | 2018-10-30 |
| KR20180125966A (ko) | 2018-11-26 |
| JP2022037132A (ja) | 2022-03-08 |
| PT3240538T (pt) | 2021-12-07 |
| ES2899929T3 (es) | 2022-03-15 |
| CA3018635C (en) | 2023-09-26 |
| IL261856B (en) | 2022-04-01 |
| CA3018635A1 (en) | 2017-09-28 |
| SI3240538T1 (sl) | 2022-02-28 |
| JP7250312B2 (ja) | 2023-04-03 |
| US10092564B2 (en) | 2018-10-09 |
| WO2017162884A1 (en) | 2017-09-28 |
| JP2019515884A (ja) | 2019-06-13 |
| EP3240538A1 (en) | 2017-11-08 |
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