EA035967B1 - Композиции для лечения гепатита в, содержащие олигонуклеотидные хелатные комплексы - Google Patents
Композиции для лечения гепатита в, содержащие олигонуклеотидные хелатные комплексы Download PDFInfo
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- EA035967B1 EA035967B1 EA201401278A EA201401278A EA035967B1 EA 035967 B1 EA035967 B1 EA 035967B1 EA 201401278 A EA201401278 A EA 201401278A EA 201401278 A EA201401278 A EA 201401278A EA 035967 B1 EA035967 B1 EA 035967B1
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- EA
- Eurasian Patent Office
- Prior art keywords
- rep
- chelate
- interferon
- calcium
- pegylated
- Prior art date
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Landscapes
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| US201261695035P | 2012-08-30 | 2012-08-30 | |
| PCT/CA2013/050379 WO2013170386A1 (en) | 2012-05-18 | 2013-05-17 | Oligonucleotide chelate complex-polypeptide compositions and methods |
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| EA201401278A1 EA201401278A1 (ru) | 2015-04-30 |
| EA035967B1 true EA035967B1 (ru) | 2020-09-07 |
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| PL2158316T3 (pl) | 2007-05-11 | 2015-10-30 | Adynxx Inc | Ekspresja genowa oraz ból |
| AU2013259402B2 (en) | 2012-05-10 | 2017-12-21 | Adynxx, Inc. | Formulations for the delivery of active ingredients |
| TWI620568B (zh) | 2012-08-30 | 2018-04-11 | 雷普利可公司 | 用於治療ｂ型肝炎及ｄ型肝炎感染之方法 |
| MX381042B (es) | 2014-07-10 | 2025-03-12 | Replicor Inc | Uso de un complejo quelato y un anàlogo de neucleòsido o neucleòtido para tratar infecciones de virus de la hepatitis b y hepatitis d. |
| EP3180434B1 (en) | 2014-08-15 | 2019-07-17 | Adynxx, Inc. | Oligonucleotide decoys for the treatment of pain |
| SG11202104636XA (en) * | 2018-11-08 | 2021-06-29 | Aligos Therapeutics Inc | S-antigen transport inhibiting oligonucleotide polymers and methods |
| US11166976B2 (en) | 2018-11-08 | 2021-11-09 | Aligos Therapeutics, Inc. | S-antigen transport inhibiting oligonucleotide polymers and methods |
| WO2024255846A1 (en) * | 2023-06-16 | 2024-12-19 | Ractigen Therapeutics | Oligonucleotide formulation |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003037272A2 (en) * | 2001-11-01 | 2003-05-08 | Sciclone Pharmaceuticals, Inc. | Thymosin alpha 1 peptide/polymer conjugates |
| WO2004076474A2 (en) * | 2003-02-26 | 2004-09-10 | Intermune, Inc. | Polyethylene glycol modified interferon compositions and methods of use thereof |
| WO2006042418A1 (en) * | 2004-10-19 | 2006-04-27 | Replicor Inc. | Antiviral oligonucleotides |
| WO2007022642A2 (en) * | 2005-08-25 | 2007-03-01 | Replicor Inc. | Anti-inflammatory molecules and their uses |
| WO2007036016A1 (en) * | 2005-09-29 | 2007-04-05 | Replicor Inc. | Therapeutic molecules and their uses |
| WO2009076679A2 (en) * | 2007-12-13 | 2009-06-18 | Alnylam Pharmaceuticals Inc. | Methods and compositions for prevention or treatment of rsv infection |
| WO2009109665A1 (en) * | 2008-03-07 | 2009-09-11 | Santaris Pharma A/S | Pharmaceutical compositions for treatment of microrna related diseases |
| WO2012021985A1 (en) * | 2010-08-20 | 2012-02-23 | Replicor Inc. | Oligonucleotide chelate complexes |
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| JP2769114B2 (ja) * | 1993-10-29 | 1998-06-25 | サイクローン・ファーマシューティカルズ | ミニマルｂ型肝炎感染症治療用医薬組成物 |
| BR0314236A (pt) * | 2002-09-13 | 2005-08-09 | Replicor Inc | Formulação de oligonucleotìdeo, composição farmacêutica, kit, composto antiviral, preparação de oligonucleotìdeo e métodos para seleção de um oligonucleotìdeo antiviral para uso como um agente antiviral, para profilaxia ou tratamento de uma infecção viral em um paciente, para tratamento profilático de câncer causado por oncovìrus, para identificação de um composto que altera a ligação de um oligonucleotìdeo a pelo menos um componente viral, para purificação da ligação de oligonucleotìdeos a pelo menos um componente viral e para enriquecimento de oligonucleotìdeos a partir de um agrupamento de oligonucleotìdeos |
| KR20060120162A (ko) * | 2003-10-27 | 2006-11-24 | 버텍스 파마슈티칼스 인코포레이티드 | Ｈｃｖ 치료용 배합물 |
| EP1928498A4 (en) * | 2005-09-29 | 2009-11-11 | Cell Biosciences Inc S | METHOD FOR THE TREATMENT OF T-CELL DISORDERS WITH TISF |
| GB0715383D0 (en) * | 2007-08-08 | 2007-09-19 | Asterion Ltd | Interferon |
| WO2009065181A1 (en) * | 2007-11-21 | 2009-05-28 | Apollo Life Sciences Limited | Nanostructures suitable for delivery of agents |
| CA2764683A1 (en) * | 2009-05-28 | 2010-12-02 | Joseph Collard | Treatment of antiviral gene related diseases by inhibition of natural antisense transcript to an antiviral gene |
| CN102762215A (zh) * | 2009-10-16 | 2012-10-31 | 葛兰素集团有限公司 | Hbv反义抑制剂 |
| TWI620568B (zh) | 2012-08-30 | 2018-04-11 | 雷普利可公司 | 用於治療ｂ型肝炎及ｄ型肝炎感染之方法 |
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