EA029180B1 - Лекарственная форма лакозамида для приема один раз в сутки - Google Patents
Лекарственная форма лакозамида для приема один раз в сутки Download PDFInfo
- Publication number
- EA029180B1 EA029180B1 EA201390804A EA201390804A EA029180B1 EA 029180 B1 EA029180 B1 EA 029180B1 EA 201390804 A EA201390804 A EA 201390804A EA 201390804 A EA201390804 A EA 201390804A EA 029180 B1 EA029180 B1 EA 029180B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- lacosamide
- dosage form
- release
- amount
- weight
- Prior art date
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Pain & Pain Management (AREA)
- Psychology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (9)
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| US41915310P | 2010-12-02 | 2010-12-02 | |
| EP10193559 | 2010-12-02 | ||
| EP10193561A EP2468261A1 (en) | 2010-12-02 | 2010-12-02 | Formulation of lacosamide |
| US201161444447P | 2011-02-18 | 2011-02-18 | |
| US201161444439P | 2011-02-18 | 2011-02-18 | |
| US201161485361P | 2011-05-12 | 2011-05-12 | |
| US201161485354P | 2011-05-12 | 2011-05-12 | |
| PCT/EP2011/006027 WO2012072256A2 (en) | 2010-12-02 | 2011-12-01 | Once daily formulation of lacosamide |
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| EP (3) | EP2646001A2 (enExample) |
| JP (2) | JP6027539B2 (enExample) |
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| CN (1) | CN103561727B (enExample) |
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| BR (1) | BR112013013525A2 (enExample) |
| CA (1) | CA2817654A1 (enExample) |
| EA (1) | EA029180B1 (enExample) |
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| MX (1) | MX2013005974A (enExample) |
| NZ (1) | NZ610701A (enExample) |
| WO (2) | WO2012084126A2 (enExample) |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2836778C1 (ru) * | 2024-04-04 | 2025-03-21 | Акционерное общество "Органика" | Фармацевтическая композиция с модифицированным высвобождением на основе полиморфов клозапина |
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| WO2007144195A2 (en) | 2006-06-15 | 2007-12-21 | Schwarz Pharma Ag | Pharmaceutical composition with synergistic anticonvulsant effect |
| CN101466390B (zh) * | 2006-06-15 | 2014-03-12 | 优时比制药有限公司 | 用于治疗难治性癫痫持续状态的肽类化合物 |
| WO2008112661A2 (en) | 2007-03-09 | 2008-09-18 | Alexza Pharmaceuticals, Inc. | Heating unit for use in a drug delivery device |
| EP2468261A1 (en) | 2010-12-02 | 2012-06-27 | UCB Pharma GmbH | Formulation of lacosamide |
| US20120308662A1 (en) * | 2011-06-01 | 2012-12-06 | Nitto Denko Corporation | Particulate preparation and method for producing the same |
| US8779355B2 (en) | 2011-12-28 | 2014-07-15 | Quest Diagnostics Investments, Inc. | Methods for detecting lacosamide by mass spectrometry |
| KR101732731B1 (ko) | 2013-04-02 | 2017-05-08 | 주식회사 바이오파마티스 | 라코사마이드(lacosamide) 또는 이의 약학적으로 허용 가능한 염의 용출 패턴 조절이 용이한 약학 조성물 |
| EP2801350B1 (en) * | 2013-05-08 | 2018-08-01 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical Formulations of Lacosamide |
| EP2878296A1 (en) | 2013-11-29 | 2015-06-03 | UCB Pharma GmbH | Pharmaceutical composition comprising lacosamide and levetiracetam |
| US20170035733A1 (en) * | 2013-11-29 | 2017-02-09 | Ucb Pharma Gmbh | Pharmaceutical composition comprising lacosamide and levetiracetam |
| EP3142644A1 (en) * | 2014-05-16 | 2017-03-22 | Vivus, Inc. | Orally administrable formulations for the controlled release of a pharmacologically active agent |
| WO2016131947A1 (en) | 2015-02-20 | 2016-08-25 | Ucb Biopharma Sprl | Combination treatment |
| JO3543B1 (ar) * | 2015-09-28 | 2020-07-05 | Applied Pharma Res | تراكيب حمض أميني إصدار معدل تعطى عن طريق الفم |
| WO2017058869A1 (en) | 2015-09-29 | 2017-04-06 | Acorda Therapeutics, Inc. | Sustained release compositions of 4-aminopyridine |
| JP6902033B2 (ja) * | 2015-12-30 | 2021-07-14 | アダマス ファーマシューティカルズ， インコーポレイテッド | 発作−関連障害の処置のための方法および組成物 |
| KR102544141B1 (ko) * | 2016-09-29 | 2023-06-16 | 에스케이케미칼 주식회사 | 라코사미드 서방성 제제 |
| CN106551900A (zh) * | 2016-12-05 | 2017-04-05 | 北京万全德众医药生物技术有限公司 | 一种拉科酰胺口服溶液及其制备工艺 |
| KR102871666B1 (ko) | 2016-12-09 | 2025-10-15 | 알렉스자 파마스티칼즈, 인크. | 간질 치료 방법 |
| EP3824906A1 (en) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| EP3746138B1 (en) | 2018-02-02 | 2025-12-10 | Alexza Pharmaceuticals, Inc. | Electrical condensation aerosol device |
| KR102083241B1 (ko) | 2018-02-14 | 2020-03-02 | 환인제약 주식회사 | 라코사미드를 함유하는 약제학적 서방성 조성물 |
| CN110833528A (zh) * | 2018-08-17 | 2020-02-25 | 北京万全德众医药生物技术有限公司 | 一种拉科酰胺脂质体冻干粉针剂及其制备方法 |
| CN109010301B (zh) * | 2018-09-05 | 2021-01-26 | 上海上药第一生化药业有限公司 | 一种拉考沙胺晶型ii片剂及其制备方法和应用 |
| CN114173763A (zh) * | 2019-06-06 | 2022-03-11 | 上海奥科达生物医药科技有限公司 | 一种拉考沙胺药物组合物及其药物制剂 |
| US12042474B2 (en) | 2019-06-06 | 2024-07-23 | Shanghai Aucta Pharmaceuticals Co., Ltd. | Lacosamide pharmaceutical composition and dosage form thereof |
| CN112022804A (zh) * | 2020-09-28 | 2020-12-04 | 健民药业集团股份有限公司 | 一种拉考沙胺口服溶液及制备方法 |
| CN115105478B (zh) * | 2021-03-17 | 2024-07-09 | 上海云晟研新生物科技有限公司 | 一种拉考沙胺药物组合物、其制备方法及应用 |
| WO2024054987A1 (en) * | 2022-09-08 | 2024-03-14 | The Children's Hospital Of Philadlphia | Gpcr latrophilin-3 as biomarker for detecting increased risk for mild brain injury and methods of use thereof for diagnosis and treatment of the same |
| CN115581676A (zh) * | 2022-09-30 | 2023-01-10 | 澳美制药(苏州)有限公司 | 拉考沙胺片剂及其制备工艺 |
| US12478587B1 (en) | 2025-02-06 | 2025-11-25 | Shanghai Aucta Pharmaceuticals Co., Ltd. | Formulation for lacosamide |
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-
2011
- 2011-12-01 WO PCT/EP2011/006026 patent/WO2012084126A2/en not_active Ceased
- 2011-12-01 WO PCT/EP2011/006027 patent/WO2012072256A2/en not_active Ceased
- 2011-12-01 AU AU2011335415A patent/AU2011335415B2/en not_active Ceased
- 2011-12-01 US US13/990,863 patent/US20130251813A1/en not_active Abandoned
- 2011-12-01 EA EA201390804A patent/EA029180B1/ru not_active IP Right Cessation
- 2011-12-01 JP JP2013541248A patent/JP6027539B2/ja active Active
- 2011-12-01 EP EP11817472.1A patent/EP2646001A2/en not_active Withdrawn
- 2011-12-01 CN CN201180057820.9A patent/CN103561727B/zh not_active Expired - Fee Related
- 2011-12-01 BR BR112013013525A patent/BR112013013525A2/pt not_active Application Discontinuation
- 2011-12-01 CA CA 2817654 patent/CA2817654A1/en not_active Abandoned
- 2011-12-01 NZ NZ610701A patent/NZ610701A/en not_active IP Right Cessation
- 2011-12-01 EP EP11791442.4A patent/EP2645997B1/en not_active Revoked
- 2011-12-01 EP EP20188230.5A patent/EP3766485A1/en not_active Withdrawn
- 2011-12-01 MX MX2013005974A patent/MX2013005974A/es not_active Application Discontinuation
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2012
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2013
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2014
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2016
- 2016-10-14 JP JP2016202383A patent/JP6357687B2/ja active Active
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2018
- 2018-07-05 US US16/027,963 patent/US20190008758A1/en not_active Abandoned
- 2018-08-21 US US16/106,655 patent/US20190054009A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2008086492A1 (en) * | 2007-01-11 | 2008-07-17 | Xenoport, Inc. | Sustained release oral dosage forms of a prodrug of r-baclofen and methods of treatment |
| WO2010060624A2 (de) * | 2008-11-27 | 2010-06-03 | Ratiopharm Gmbh | Trockenverarbeitung und neue formen von lacosamid |
| WO2011055385A1 (en) * | 2009-11-03 | 2011-05-12 | Lupin Limited | Modified release formulation of lacosamide |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2836778C1 (ru) * | 2024-04-04 | 2025-03-21 | Акционерное общество "Органика" | Фармацевтическая композиция с модифицированным высвобождением на основе полиморфов клозапина |
Also Published As
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| CN103561727B (zh) | 2018-03-27 |
| US20190054009A1 (en) | 2019-02-21 |
| CN103561727A (zh) | 2014-02-05 |
| NZ610701A (en) | 2015-06-26 |
| CA2817654A1 (en) | 2012-06-07 |
| US20190008758A1 (en) | 2019-01-10 |
| EP2646001A2 (en) | 2013-10-09 |
| MX2013005974A (es) | 2013-07-29 |
| JP2013545762A (ja) | 2013-12-26 |
| EP2645997B1 (en) | 2022-08-10 |
| IL226231B (en) | 2018-01-31 |
| EA201390804A1 (ru) | 2013-10-30 |
| AU2011335415B2 (en) | 2016-05-19 |
| EP3766485A1 (en) | 2021-01-20 |
| KR20150034579A (ko) | 2015-04-03 |
| JP2017031206A (ja) | 2017-02-09 |
| JP6027539B2 (ja) | 2016-11-16 |
| BR112013013525A2 (pt) | 2016-10-18 |
| WO2012084126A2 (en) | 2012-06-28 |
| ZA201303289B (en) | 2014-02-26 |
| WO2012072256A2 (en) | 2012-06-07 |
| JP6357687B2 (ja) | 2018-07-18 |
| WO2012072256A3 (en) | 2014-01-23 |
| US20130251813A1 (en) | 2013-09-26 |
| KR101980386B1 (ko) | 2019-05-20 |
| WO2012084126A3 (en) | 2013-05-02 |
| AU2011335415A1 (en) | 2013-06-20 |
| EP2645997A2 (en) | 2013-10-09 |
| IL226231A0 (en) | 2013-07-31 |
| US20150104507A1 (en) | 2015-04-16 |
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