EA028230B1 - Применение негликозилированного белка аполипопротеина a-iv для лечения сахарного диабета 2 типа - Google Patents
Применение негликозилированного белка аполипопротеина a-iv для лечения сахарного диабета 2 типа Download PDFInfo
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- EA028230B1 EA028230B1 EA201491369A EA201491369A EA028230B1 EA 028230 B1 EA028230 B1 EA 028230B1 EA 201491369 A EA201491369 A EA 201491369A EA 201491369 A EA201491369 A EA 201491369A EA 028230 B1 EA028230 B1 EA 028230B1
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
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- Endocrinology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| USPCT/US2012/021802 | 2012-01-19 | ||
| PCT/US2012/021802 WO2012100010A1 (en) | 2011-01-19 | 2012-01-19 | Apolipoprotein aiv as an antidiabetic peptide |
| US201261675692P | 2012-07-25 | 2012-07-25 | |
| US61/675,692 | 2012-07-25 | ||
| PCT/US2012/066314 WO2013109342A1 (en) | 2012-01-19 | 2012-11-21 | Method of treating diabetes using non-glycosylated apolipoprotein a-iv |
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| EA201491369A1 EA201491369A1 (ru) | 2015-03-31 |
| EA028230B1 true EA028230B1 (ru) | 2017-10-31 |
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| EA201491369A EA028230B1 (ru) | 2012-01-19 | 2012-11-21 | Применение негликозилированного белка аполипопротеина a-iv для лечения сахарного диабета 2 типа |
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| US (1) | US9951120B2 (enExample) |
| EP (1) | EP2804618B1 (enExample) |
| JP (1) | JP6310398B2 (enExample) |
| KR (1) | KR20140117565A (enExample) |
| CN (1) | CN104066436B (enExample) |
| AU (1) | AU2012366182B2 (enExample) |
| BR (1) | BR112014017141A2 (enExample) |
| CA (1) | CA2860782A1 (enExample) |
| EA (1) | EA028230B1 (enExample) |
| HK (1) | HK1203823A1 (enExample) |
| IL (1) | IL233351A (enExample) |
| MX (1) | MX357071B (enExample) |
| WO (1) | WO2013109342A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX342020B (es) | 2011-01-19 | 2016-09-08 | Univ Cincinnati | Apolipoproteina a-iv como un peptido antidiabetico. |
| HK1203823A1 (en) | 2012-01-19 | 2015-11-06 | University Of Cincinnati | Method of treating diabetes using non-glycosylated apolipoprotein a-iv |
| WO2014018763A2 (en) * | 2012-07-25 | 2014-01-30 | University Of Cincinnati | Method of treating type i diabetes using apolipoprotein aiv |
| WO2014018079A1 (en) | 2012-07-25 | 2014-01-30 | University Of Cincinnati | Method of treating hyperglycemic disorders using apoliprotein aiv |
| EP3159354B1 (en) * | 2014-06-23 | 2020-09-09 | Toagosei Co., Ltd. | Novel synthetic peptide and use thereof |
| CN112546201A (zh) * | 2019-09-26 | 2021-03-26 | 中国科学院生物物理研究所 | 人工脂蛋白颗粒apoA-Ⅳ脂肪体在治疗和/或预防糖尿病中的应用 |
| CN113018459A (zh) * | 2021-03-09 | 2021-06-25 | 百码科技(深圳)有限公司 | 一种基因治疗减肥的生物药剂及其制备方法 |
| CN112891561A (zh) * | 2021-03-09 | 2021-06-04 | 百码科技(深圳)有限公司 | 一种基因治疗脂肪肝的生物药剂及其制备方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993015198A1 (fr) * | 1992-01-27 | 1993-08-05 | Rhone-Poulenc Rorer S.A. | Polypeptides derives de l'apolipoproteine aiv humaine, leur preparation et leur utilisation |
| WO2009116861A2 (en) * | 2008-03-21 | 2009-09-24 | Podiceps B.V. | Diagnostic of pre-symptomatic metabolic syndrome |
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| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
| AU7242394A (en) | 1993-05-28 | 1994-12-20 | Merck & Co., Inc. | Method to control appetite and treat obesity |
| US6729075B2 (en) * | 2000-10-19 | 2004-05-04 | Wenger Corporation | Audience seating system |
| NZ537006A (en) | 2002-05-17 | 2008-01-31 | Esperion Therapeutics Inc | The use of apolipoprotein A-I Milano, for the manufacture ofa composition for treating preventing or reducing ischemic reperfusion injury in a tissue or organ |
| AU2007272954A1 (en) * | 2006-07-11 | 2008-01-17 | Harkness Pharmaceuticals, Inc. | Methods of treating obesity using satiety factors |
| US20100267052A1 (en) | 2006-09-01 | 2010-10-21 | American Type Culture Collection | Compositions and methods for diagnosis and treatment of type 2 diabetes |
| CN101747305B (zh) | 2008-11-28 | 2014-06-18 | 中国医学科学院药物研究所 | 硝克柳胺化合物晶v型、其制法和其药物组合物与用途 |
| ES2558751T3 (es) * | 2010-08-30 | 2016-02-08 | F. Hoffmann-La Roche Ag | Alimento alcalino |
| MX342020B (es) | 2011-01-19 | 2016-09-08 | Univ Cincinnati | Apolipoproteina a-iv como un peptido antidiabetico. |
| HK1203823A1 (en) | 2012-01-19 | 2015-11-06 | University Of Cincinnati | Method of treating diabetes using non-glycosylated apolipoprotein a-iv |
| WO2014018763A2 (en) | 2012-07-25 | 2014-01-30 | University Of Cincinnati | Method of treating type i diabetes using apolipoprotein aiv |
| WO2014018079A1 (en) | 2012-07-25 | 2014-01-30 | University Of Cincinnati | Method of treating hyperglycemic disorders using apoliprotein aiv |
-
2012
- 2012-11-21 HK HK15104317.1A patent/HK1203823A1/xx unknown
- 2012-11-21 US US14/373,259 patent/US9951120B2/en active Active
- 2012-11-21 WO PCT/US2012/066314 patent/WO2013109342A1/en not_active Ceased
- 2012-11-21 KR KR1020147023031A patent/KR20140117565A/ko not_active Withdrawn
- 2012-11-21 BR BR112014017141A patent/BR112014017141A2/pt not_active IP Right Cessation
- 2012-11-21 CA CA2860782A patent/CA2860782A1/en not_active Abandoned
- 2012-11-21 EA EA201491369A patent/EA028230B1/ru not_active IP Right Cessation
- 2012-11-21 EP EP12795976.5A patent/EP2804618B1/en active Active
- 2012-11-21 AU AU2012366182A patent/AU2012366182B2/en not_active Expired - Fee Related
- 2012-11-21 CN CN201280067554.2A patent/CN104066436B/zh not_active Expired - Fee Related
- 2012-11-21 JP JP2014553292A patent/JP6310398B2/ja not_active Expired - Fee Related
- 2012-11-21 MX MX2014008829A patent/MX357071B/es active IP Right Grant
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2014
- 2014-06-24 IL IL233351A patent/IL233351A/en active IP Right Grant
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993015198A1 (fr) * | 1992-01-27 | 1993-08-05 | Rhone-Poulenc Rorer S.A. | Polypeptides derives de l'apolipoproteine aiv humaine, leur preparation et leur utilisation |
| WO2009116861A2 (en) * | 2008-03-21 | 2009-09-24 | Podiceps B.V. | Diagnostic of pre-symptomatic metabolic syndrome |
Non-Patent Citations (1)
| Title |
|---|
| BIOLOGICAL ABSTRACTS, 1 July 2002, Philadelphia, PA, US; "Physiology of the small intestine in the glycemic control and the treatment of diabetes mellitus" XP002676412 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2804618B1 (en) | 2018-03-07 |
| CA2860782A1 (en) | 2013-07-25 |
| BR112014017141A2 (pt) | 2019-09-24 |
| AU2012366182A8 (en) | 2015-06-18 |
| IL233351A0 (en) | 2014-08-31 |
| AU2012366182B2 (en) | 2017-08-17 |
| CN104066436A (zh) | 2014-09-24 |
| CN104066436B (zh) | 2016-12-14 |
| US9951120B2 (en) | 2018-04-24 |
| EA201491369A1 (ru) | 2015-03-31 |
| AU2012366182A1 (en) | 2014-08-07 |
| IL233351A (en) | 2016-12-29 |
| HK1203823A1 (en) | 2015-11-06 |
| KR20140117565A (ko) | 2014-10-07 |
| JP2015506942A (ja) | 2015-03-05 |
| JP6310398B2 (ja) | 2018-04-11 |
| EP2804618A1 (en) | 2014-11-26 |
| MX357071B (es) | 2018-06-22 |
| MX2014008829A (es) | 2014-10-24 |
| WO2013109342A1 (en) | 2013-07-25 |
| US20150011469A1 (en) | 2015-01-08 |
| WO2013109342A8 (en) | 2014-09-04 |
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