EA027373B1 - Способ разделения рацемического 3-карбокси-4-фенилпирролидин-2-она с помощью 3-(s)-бензоилоксихинуклидина - Google Patents
Способ разделения рацемического 3-карбокси-4-фенилпирролидин-2-она с помощью 3-(s)-бензоилоксихинуклидина Download PDFInfo
- Publication number
- EA027373B1 EA027373B1 EA201691190A EA201691190A EA027373B1 EA 027373 B1 EA027373 B1 EA 027373B1 EA 201691190 A EA201691190 A EA 201691190A EA 201691190 A EA201691190 A EA 201691190A EA 027373 B1 EA027373 B1 EA 027373B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- carboxy
- phenylpyrrolidin
- benzoyloxyquinuclidine
- salt
- water
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LVP-13-209A LV15015B (lv) | 2013-12-13 | 2013-12-13 | 3-karboksi-4-(R)-fenilpirolidin-2-ona sāls un tā pielietošana |
| PCT/IB2014/066846 WO2015087291A1 (en) | 2013-12-13 | 2014-12-12 | 3-carboxy-4-(r)-phenylpyrrolydine-2-one salt and its use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201691190A1 EA201691190A1 (ru) | 2016-12-30 |
| EA027373B1 true EA027373B1 (ru) | 2017-07-31 |
Family
ID=52462958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201691190A EA027373B1 (ru) | 2013-12-13 | 2014-12-12 | Способ разделения рацемического 3-карбокси-4-фенилпирролидин-2-она с помощью 3-(s)-бензоилоксихинуклидина |
Country Status (4)
| Country | Link |
|---|---|
| EA (1) | EA027373B1 (xx) |
| LV (1) | LV15015B (xx) |
| UA (1) | UA114161C2 (xx) |
| WO (1) | WO2015087291A1 (xx) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LV13635B (en) | 2006-02-23 | 2008-01-20 | Olainfarm As | Enzymatic resolution of racemic 3-aryl-4-aminobutyric acids |
| LV13630B (en) | 2006-03-16 | 2007-12-20 | Olainfarm As | Method of preparation and use of pharmaceutically active n-carbamoylmethyl-4(r)-phenyl-2-pyrrolidinone |
-
2013
- 2013-12-13 LV LVP-13-209A patent/LV15015B/lv unknown
-
2014
- 2014-12-12 EA EA201691190A patent/EA027373B1/ru unknown
- 2014-12-12 UA UAA201606170A patent/UA114161C2/uk unknown
- 2014-12-12 WO PCT/IB2014/066846 patent/WO2015087291A1/en active Application Filing
Non-Patent Citations (2)
| Title |
|---|
| ELIEL, E. L.; WILEN, S. H.; MANDER, L. N.: "CHEMICAL SEPARATION OF ENANTIOMERS VIA DIASTEREOMERS", STEREOCHEMISTRY OF ORGANIC COMPOUNDS, XX, XX, 1 January 1994 (1994-01-01), XX, pages 322 - 336, XP002459712 * |
| SOBOCINSKA MARIA; ZOBACHEVA MAIA M.; PEREKALIN VSEVOLOD V.; KUPRYSZEWSKI GOTFRYD: "Configuration of 4-aryl-2-pyrrolidinones and their 3-carboxy derivatives", POLISH JOURNAL OF CHEMISTRY, POLSKIE TOWARZYSTWO CHEMICZNE, POLISH CHEMICAL SOCIETY, PL, vol. 53, 1 January 1979 (1979-01-01), PL, pages 435 - 446, XP002737419, ISSN: 0137-5083 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015087291A1 (en) | 2015-06-18 |
| LV15015B (lv) | 2015-12-20 |
| EA201691190A1 (ru) | 2016-12-30 |
| UA114161C2 (xx) | 2017-04-25 |
| LV15015A (lv) | 2015-06-20 |
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