LV15015A - 3-karboksi-4-(R)-fenilpirolidin-2-ona sāls un tā pielietošana - Google Patents

3-karboksi-4-(R)-fenilpirolidin-2-ona sāls un tā pielietošana

Info

Publication number
LV15015A
LV15015A LVP-13-209A LV130209A LV15015A LV 15015 A LV15015 A LV 15015A LV 130209 A LV130209 A LV 130209A LV 15015 A LV15015 A LV 15015A
Authority
LV
Latvia
Prior art keywords
carboxy
phenylpyrrolidinone
salt
phenylpyrrolidin
racemic
Prior art date
Application number
LVP-13-209A
Other languages
English (en)
Other versions
LV15015B (lv
Inventor
Gaļina KUHAREVA
Evgenij Matiushenkov
Original Assignee
Olainfarm, A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olainfarm, A/S filed Critical Olainfarm, A/S
Priority to LVP-13-209A priority Critical patent/LV15015B/lv
Priority to EA201691190A priority patent/EA027373B1/ru
Priority to UAA201606170A priority patent/UA114161C2/uk
Priority to PCT/IB2014/066846 priority patent/WO2015087291A1/en
Publication of LV15015A publication Critical patent/LV15015A/lv
Publication of LV15015B publication Critical patent/LV15015B/lv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Izgudrots jauns paņēmiens 3-karboksi-4-(R)-fenilpirolidin-2-ona iegūšanai no racēmiskā 3-karboksi-4-(R,S)-fenilpirolidin-2-ona, kurā racemāta sadalīšanai izmanto 3-(S)-benzoiloksihinuklidīnu.
LVP-13-209A 2013-12-13 2013-12-13 3-karboksi-4-(R)-fenilpirolidin-2-ona sāls un tā pielietošana LV15015B (lv)

Priority Applications (4)

Application Number Priority Date Filing Date Title
LVP-13-209A LV15015B (lv) 2013-12-13 2013-12-13 3-karboksi-4-(R)-fenilpirolidin-2-ona sāls un tā pielietošana
EA201691190A EA027373B1 (ru) 2013-12-13 2014-12-12 Способ разделения рацемического 3-карбокси-4-фенилпирролидин-2-она с помощью 3-(s)-бензоилоксихинуклидина
UAA201606170A UA114161C2 (xx) 2013-12-13 2014-12-12 Сіль 3-карбокси-4-(r)-фенілпіролідин-2-ону та її застосування
PCT/IB2014/066846 WO2015087291A1 (en) 2013-12-13 2014-12-12 3-carboxy-4-(r)-phenylpyrrolydine-2-one salt and its use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LVP-13-209A LV15015B (lv) 2013-12-13 2013-12-13 3-karboksi-4-(R)-fenilpirolidin-2-ona sāls un tā pielietošana

Publications (2)

Publication Number Publication Date
LV15015A true LV15015A (lv) 2015-06-20
LV15015B LV15015B (lv) 2015-12-20

Family

ID=52462958

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-13-209A LV15015B (lv) 2013-12-13 2013-12-13 3-karboksi-4-(R)-fenilpirolidin-2-ona sāls un tā pielietošana

Country Status (4)

Country Link
EA (1) EA027373B1 (lv)
LV (1) LV15015B (lv)
UA (1) UA114161C2 (lv)
WO (1) WO2015087291A1 (lv)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LV13635B (en) 2006-02-23 2008-01-20 Olainfarm As Enzymatic resolution of racemic 3-aryl-4-aminobutyric acids
LV13630B (en) 2006-03-16 2007-12-20 Olainfarm As Method of preparation and use of pharmaceutically active n-carbamoylmethyl-4(r)-phenyl-2-pyrrolidinone

Also Published As

Publication number Publication date
UA114161C2 (xx) 2017-04-25
LV15015B (lv) 2015-12-20
EA201691190A1 (ru) 2016-12-30
WO2015087291A1 (en) 2015-06-18
EA027373B1 (ru) 2017-07-31

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LV15015A (lv) 3-karboksi-4-(R)-fenilpirolidin-2-ona sāls un tā pielietošana