EA023928B1 - Композиция опухолеассоциированных пептидов и относящаяся к ним противораковая вакцина - Google Patents

Композиция опухолеассоциированных пептидов и относящаяся к ним противораковая вакцина Download PDF

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Publication number
EA023928B1
EA023928B1 EA201300322A EA201300322A EA023928B1 EA 023928 B1 EA023928 B1 EA 023928B1 EA 201300322 A EA201300322 A EA 201300322A EA 201300322 A EA201300322 A EA 201300322A EA 023928 B1 EA023928 B1 EA 023928B1
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EA
Eurasian Patent Office
Prior art keywords
peptide
peptides
cells
cell
cancer
Prior art date
Application number
EA201300322A
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English (en)
Russian (ru)
Other versions
EA201300322A1 (ru
Inventor
Харпрет Сингх
Оливер Шор
Клаудиа Траутвайн
Норберт Хильф
Тони Вайншенк
Штеффен Вальтер
Петер Левандровски
Original Assignee
Имматикс Байотекнолоджиз Гмбх
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Application filed by Имматикс Байотекнолоджиз Гмбх filed Critical Имматикс Байотекнолоджиз Гмбх
Publication of EA201300322A1 publication Critical patent/EA201300322A1/ru
Publication of EA023928B1 publication Critical patent/EA023928B1/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/19Dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/20Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24Antigen-presenting cells [APC]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4264Cancer antigens from embryonic or fetal origin
    • A61K40/4266Carcinoembryonic antigen [CEA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EA201300322A 2007-07-27 2008-07-25 Композиция опухолеассоциированных пептидов и относящаяся к ним противораковая вакцина EA023928B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07014796 2007-07-27
US95310907P 2007-07-31 2007-07-31
US98124107P 2007-10-19 2007-10-19

Publications (2)

Publication Number Publication Date
EA201300322A1 EA201300322A1 (ru) 2013-10-30
EA023928B1 true EA023928B1 (ru) 2016-07-29

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EA201300322A EA023928B1 (ru) 2007-07-27 2008-07-25 Композиция опухолеассоциированных пептидов и относящаяся к ним противораковая вакцина
EA201000208A EA018457B1 (ru) 2007-07-27 2008-07-25 Композиция опухолеассоциированных пептидов и относящаяся к ним противораковая вакцина

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Country Status (20)

Country Link
US (1) US7994276B2 (enExample)
EP (2) EP2178557B1 (enExample)
JP (2) JP5352586B2 (enExample)
KR (1) KR101167392B1 (enExample)
CN (2) CN101765434B (enExample)
AU (1) AU2008281013B2 (enExample)
BR (1) BRPI0814140A2 (enExample)
CA (2) CA2817054C (enExample)
DK (1) DK2567707T3 (enExample)
EA (2) EA023928B1 (enExample)
ES (1) ES2608583T3 (enExample)
HU (1) HUE032379T2 (enExample)
LT (1) LT2567707T (enExample)
MX (1) MX2010001088A (enExample)
NZ (1) NZ582823A (enExample)
PL (1) PL2567707T3 (enExample)
PT (1) PT2567707T (enExample)
SI (1) SI2567707T1 (enExample)
UA (2) UA103882C2 (enExample)
WO (1) WO2009015841A1 (enExample)

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ES2608583T3 (es) 2017-04-12
KR101167392B1 (ko) 2012-07-19
CA2817054C (en) 2017-02-28
EA201000208A1 (ru) 2011-02-28
EP2567707A3 (en) 2013-07-24
EP2178557A1 (en) 2010-04-28
UA103882C2 (uk) 2013-12-10
HUE032379T2 (en) 2017-09-28
JP2013165721A (ja) 2013-08-29
CA2694771A1 (en) 2009-02-05
CN101765434A (zh) 2010-06-30
NZ582823A (en) 2012-04-27
CN103360466B (zh) 2016-08-03
AU2008281013A1 (en) 2009-02-05
JP2010534627A (ja) 2010-11-11
KR20100040875A (ko) 2010-04-21
UA117216C2 (uk) 2018-07-10
EP2567707A2 (en) 2013-03-13
MX2010001088A (es) 2010-06-01
US20090148400A1 (en) 2009-06-11
JP5746251B2 (ja) 2015-07-08
PL2567707T3 (pl) 2017-03-31
CN103360466A (zh) 2013-10-23
DK2567707T3 (en) 2017-07-31
WO2009015841A1 (en) 2009-02-05
LT2567707T (lt) 2017-01-10
BRPI0814140A2 (pt) 2017-03-28
CN101765434B (zh) 2014-12-17
US7994276B2 (en) 2011-08-09
AU2008281013B2 (en) 2012-06-28
JP5352586B2 (ja) 2013-11-27
HK1182923A1 (en) 2013-12-13
SI2567707T1 (sl) 2017-01-31
CA2817054A1 (en) 2009-02-05
EA201300322A1 (ru) 2013-10-30
PT2567707T (pt) 2016-12-27
EA018457B1 (ru) 2013-08-30
EP2178557B1 (en) 2017-03-01
EP2567707B1 (en) 2016-10-05
AU2008281013A2 (en) 2010-04-29

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