DK2567707T3 - Composition of tumour-associated peptides and related anti-cancer vaccine - Google Patents

Composition of tumour-associated peptides and related anti-cancer vaccine Download PDF

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Publication number
DK2567707T3
DK2567707T3 DK12187307.9T DK12187307T DK2567707T3 DK 2567707 T3 DK2567707 T3 DK 2567707T3 DK 12187307 T DK12187307 T DK 12187307T DK 2567707 T3 DK2567707 T3 DK 2567707T3
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Denmark
Prior art keywords
tumour
composition
cancer vaccine
associated peptides
related anti
Prior art date
Application number
DK12187307.9T
Other languages
English (en)
Inventor
Oliver Schoor
Norbert Hilf
Toni Weinschenk
Steffen Walter
Claudia Trautwein
Harpreet Singh
Peter Lewandrowski
Original Assignee
Immatics Biotechnologies Gmbh
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Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh
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Publication of DK2567707T3 publication Critical patent/DK2567707T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4615—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/46448—Cancer antigens from embryonic or fetal origin
    • A61K39/464482—Carcinoembryonic antigen [CEA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK12187307.9T 2007-07-27 2008-07-25 Composition of tumour-associated peptides and related anti-cancer vaccine DK2567707T3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP07014796 2007-07-27
US95310907P 2007-07-31 2007-07-31
US98124107P 2007-10-19 2007-10-19
EP08785105.1A EP2178557B1 (en) 2007-07-27 2008-07-25 Composition of tumour-associated peptides and related anti-cancer vaccine

Publications (1)

Publication Number Publication Date
DK2567707T3 true DK2567707T3 (en) 2017-07-31

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Family Applications (1)

Application Number Title Priority Date Filing Date
DK12187307.9T DK2567707T3 (en) 2007-07-27 2008-07-25 Composition of tumour-associated peptides and related anti-cancer vaccine

Country Status (21)

Country Link
US (1) US7994276B2 (da)
EP (2) EP2567707B1 (da)
JP (2) JP5352586B2 (da)
KR (1) KR101167392B1 (da)
CN (2) CN101765434B (da)
AU (1) AU2008281013B2 (da)
BR (1) BRPI0814140A2 (da)
CA (2) CA2694771A1 (da)
DK (1) DK2567707T3 (da)
EA (2) EA023928B1 (da)
ES (1) ES2608583T3 (da)
HK (1) HK1182923A1 (da)
HU (1) HUE032379T2 (da)
LT (1) LT2567707T (da)
MX (1) MX2010001088A (da)
NZ (1) NZ582823A (da)
PL (1) PL2567707T3 (da)
PT (1) PT2567707T (da)
SI (1) SI2567707T1 (da)
UA (2) UA117216C2 (da)
WO (1) WO2009015841A1 (da)

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Also Published As

Publication number Publication date
CA2694771A1 (en) 2009-02-05
EA023928B1 (ru) 2016-07-29
AU2008281013B2 (en) 2012-06-28
PT2567707T (pt) 2016-12-27
CN101765434A (zh) 2010-06-30
AU2008281013A2 (en) 2010-04-29
US7994276B2 (en) 2011-08-09
EP2567707B1 (en) 2016-10-05
US20090148400A1 (en) 2009-06-11
EP2178557A1 (en) 2010-04-28
NZ582823A (en) 2012-04-27
CN101765434B (zh) 2014-12-17
AU2008281013A1 (en) 2009-02-05
EA018457B1 (ru) 2013-08-30
EP2178557B1 (en) 2017-03-01
EA201000208A1 (ru) 2011-02-28
CN103360466B (zh) 2016-08-03
EA201300322A1 (ru) 2013-10-30
LT2567707T (lt) 2017-01-10
BRPI0814140A2 (pt) 2017-03-28
UA103882C2 (uk) 2013-12-10
HUE032379T2 (en) 2017-09-28
CN103360466A (zh) 2013-10-23
JP5352586B2 (ja) 2013-11-27
PL2567707T3 (pl) 2017-03-31
MX2010001088A (es) 2010-06-01
JP2013165721A (ja) 2013-08-29
JP2010534627A (ja) 2010-11-11
KR101167392B1 (ko) 2012-07-19
JP5746251B2 (ja) 2015-07-08
KR20100040875A (ko) 2010-04-21
CA2817054C (en) 2017-02-28
WO2009015841A1 (en) 2009-02-05
UA117216C2 (uk) 2018-07-10
SI2567707T1 (sl) 2017-01-31
EP2567707A2 (en) 2013-03-13
HK1182923A1 (zh) 2013-12-13
EP2567707A3 (en) 2013-07-24
CA2817054A1 (en) 2009-02-05
ES2608583T3 (es) 2017-04-12

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