EA019757B1 - Фармацевтическая композиция с синергетическим противосудорожным эффектом - Google Patents
Фармацевтическая композиция с синергетическим противосудорожным эффектом Download PDFInfo
- Publication number
- EA019757B1 EA019757B1 EA200900020A EA200900020A EA019757B1 EA 019757 B1 EA019757 B1 EA 019757B1 EA 200900020 A EA200900020 A EA 200900020A EA 200900020 A EA200900020 A EA 200900020A EA 019757 B1 EA019757 B1 EA 019757B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- lacosamide
- pharmaceutical composition
- compound
- levetiracetam
- seizures
- Prior art date
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Landscapes
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Applications Claiming Priority (5)
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| US81396706P | 2006-06-15 | 2006-06-15 | |
| EP06021469 | 2006-10-12 | ||
| EP06021470A EP1920780A1 (en) | 2006-10-12 | 2006-10-12 | Peptide compounds for the treatment of hyperexcitability disorders |
| EP06024241A EP1925314A1 (en) | 2006-11-22 | 2006-11-22 | Pharmaceutical composition with synergistic anticonvulsant effect |
| PCT/EP2007/005304 WO2007144195A2 (en) | 2006-06-15 | 2007-06-15 | Pharmaceutical composition with synergistic anticonvulsant effect |
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| EA201300702A EA027836B1 (ru) | 2006-06-15 | 2007-06-15 | Фармацевтическая комбинация для профилактики, облегчения и/или лечения приступов эпилепсии и ее применение |
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| ATE228358T1 (de) * | 2001-03-21 | 2002-12-15 | Sanol Arznei Schwarz Gmbh | Neue verwendung einer klasse von peptidverbindungen zur behandlung von allodynie oder andere arten von chronischen oder phantomschmerzen |
| US20100256179A1 (en) * | 2004-03-26 | 2010-10-07 | Ucb Pharma Gmbh | Combination therapy for pain in painful diabetic neuropathy |
| JP2007532607A (ja) * | 2004-04-16 | 2007-11-15 | シュバルツ ファルマ アクチェンゲゼルシャフト | 慢性頭痛の予防及び治療のためのペプチド化合物の使用 |
| EP1604655A1 (en) | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating pain in trigeminal neuralgia |
| ATE471717T1 (de) * | 2004-08-27 | 2010-07-15 | Ucb Pharma Gmbh | Verwendung von peptidverbindungen zur behandlung von schmerzen durch knochenkrebs, chemotherapie- und nucleosid-bedingten schmerzen |
| EP1642889A1 (en) * | 2004-10-02 | 2006-04-05 | Schwarz Pharma Ag | Improved synthesis scheme for lacosamide |
| EP1754476A1 (en) * | 2005-08-18 | 2007-02-21 | Schwarz Pharma Ag | Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia |
| EP1873527A1 (en) * | 2006-06-30 | 2008-01-02 | Schwarz Pharma Ag | Method for identifying CRMP modulators |
| CN101466390B (zh) | 2006-06-15 | 2014-03-12 | 优时比制药有限公司 | 用于治疗难治性癫痫持续状态的肽类化合物 |
| EP2037965B1 (en) * | 2006-06-15 | 2017-08-30 | UCB Pharma GmbH | Pharmaceutical composition with synergistic anticonvulsant effect |
| JP2010024156A (ja) * | 2008-07-16 | 2010-02-04 | Ucb Pharma Sa | レベチラセタムを含む医薬組成物 |
| EP2509939A4 (en) | 2009-09-23 | 2013-09-18 | Univ North Carolina | NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2- (ACYLAMIDO) ACETIC ACID AND 2- (ACYLAMIDO) PROPIONIC ACIDS: POWERFUL NEUROLOGIC AGENTS |
| EP2468261A1 (en) | 2010-12-02 | 2012-06-27 | UCB Pharma GmbH | Formulation of lacosamide |
| JP6027539B2 (ja) | 2010-12-02 | 2016-11-16 | ウーツェーベー ファルマ ゲーエムベーハーＵｃｂ Ｐｈａｒｍａ Ｇｍｂｈ | ラコサミドの１日１回投与用製剤 |
| EP2878296A1 (en) * | 2013-11-29 | 2015-06-03 | UCB Pharma GmbH | Pharmaceutical composition comprising lacosamide and levetiracetam |
| EP3074004A2 (en) * | 2013-11-29 | 2016-10-05 | UCB Pharma GmbH | Pharmaceutical composition comprising lacosamide and levetiracetam |
| UA121965C2 (uk) | 2014-01-21 | 2020-08-25 | Янссен Фармацевтика Нв | Комбінації, які містять позитивні алостеричні модулятори або ортостеричні агоністи метаботропного глутаматергічного рецептора 2 підтипу, та їх застосування |
| KR102502485B1 (ko) * | 2014-01-21 | 2023-02-21 | 얀센 파마슈티카 엔.브이. | 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도 |
| MX2018008021A (es) | 2015-12-30 | 2018-11-09 | Adamas Pharmaceuticals Inc | Metodos y composiciones para el tratamiento de trastornos relacionados con convulsiones. |
| PL3464336T3 (pl) | 2016-06-01 | 2022-05-16 | Athira Pharma, Inc. | Związki |
| US11806405B1 (en) | 2021-07-19 | 2023-11-07 | Zeno Management, Inc. | Immunoconjugates and methods |
| CN116359512A (zh) * | 2023-03-08 | 2023-06-30 | 南方医科大学南方医院 | Crmp3作为癫痫的诊断、治疗、预后分子标志物的应用 |
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| EP1541138A1 (en) * | 2003-12-05 | 2005-06-15 | Schwarz Pharma Ag | Novel use of peptide compounds for treating status epilepticus or related conditions |
| WO2006079547A2 (en) * | 2005-01-28 | 2006-08-03 | Schwarz Pharma Ag | Spm 927 for add-on therapy of schizophrenia |
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| DE2937698A1 (de) * | 1979-09-18 | 1981-04-02 | A. Nattermann & Cie GmbH, 5000 Köln | N-propionylsarcosinanilide, deren herstellungsverfahren und arzneimittel auf deren basis |
| FR2480747A1 (fr) * | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
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| FR2518088B1 (fr) * | 1981-12-16 | 1987-11-27 | Roques Bernard | Nouveaux derives d'aminoacides, et leur application therapeutique |
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| JPH0680079B2 (ja) * | 1984-11-09 | 1994-10-12 | エーザイ株式会社 | ポリペプチド |
| US5654301A (en) | 1985-02-15 | 1997-08-05 | Research Corporation Technologies, Inc. | Amino acid derivative anticonvulsant |
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| JPH03506045A (ja) * | 1989-05-19 | 1991-12-26 | リサーチ・コーポレイション・テクノロジーズ・インコーポレイテッド | アミノ酸誘導体抗けいれん薬 |
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