DK1809273T3 - Anvendelse af 2-phenyl-1,2-ethandiol-(di)carbamater til behandling af epileptogenese - Google Patents

Anvendelse af 2-phenyl-1,2-ethandiol-(di)carbamater til behandling af epileptogenese

Info

Publication number
DK1809273T3
DK1809273T3 DK05810288.0T DK05810288T DK1809273T3 DK 1809273 T3 DK1809273 T3 DK 1809273T3 DK 05810288 T DK05810288 T DK 05810288T DK 1809273 T3 DK1809273 T3 DK 1809273T3
Authority
DK
Denmark
Prior art keywords
phenyl
group
alkyl
epileptogenesis
ethanediol
Prior art date
Application number
DK05810288.0T
Other languages
English (en)
Inventor
Yong Moon Choi
Robert Gordon
Gerald P Novak
Carlos R Plata-Salaman
Roy E Twyman
Steve H White
Boyu Zhao
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1809273T3 publication Critical patent/DK1809273T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK05810288.0T 2004-09-16 2005-09-15 Anvendelse af 2-phenyl-1,2-ethandiol-(di)carbamater til behandling af epileptogenese DK1809273T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US61027604P 2004-09-16 2004-09-16
US69862505P 2005-07-12 2005-07-12
US70724205P 2005-08-11 2005-08-11
PCT/US2005/032861 WO2006033947A2 (en) 2004-09-16 2005-09-15 Use of 2-phenyl-1, 2-ethanediol- (di) carbamates for treating epileptogenesis and epilepsy

Publications (1)

Publication Number Publication Date
DK1809273T3 true DK1809273T3 (da) 2010-08-02

Family

ID=36087909

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05810288.0T DK1809273T3 (da) 2004-09-16 2005-09-15 Anvendelse af 2-phenyl-1,2-ethandiol-(di)carbamater til behandling af epileptogenese

Country Status (23)

Country Link
US (2) US20060194873A1 (da)
JP (1) JP2008513466A (da)
KR (1) KR20070057939A (da)
CN (1) CN101056629B (da)
AT (1) ATE464044T1 (da)
AU (1) AU2005287174B2 (da)
BR (1) BRPI0515374A (da)
CA (1) CA2580640A1 (da)
CO (1) CO6382111A2 (da)
CR (1) CR9053A (da)
DE (1) DE602005020667D1 (da)
DK (1) DK1809273T3 (da)
EA (1) EA200700642A1 (da)
ES (1) ES2342185T3 (da)
HK (1) HK1105583A1 (da)
HR (1) HRP20100304T1 (da)
IL (1) IL181910A0 (da)
MX (1) MX2007003278A (da)
NO (1) NO20071921L (da)
NZ (1) NZ553813A (da)
PT (1) PT1809273E (da)
RS (1) RS51269B (da)
WO (1) WO2006033947A2 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2378955A1 (en) * 1999-08-10 2001-02-15 Uab Research Foundation Use of gaba agonists for treatment of spastic disorders, convulsions, and epilepsy
KR20110049901A (ko) * 2004-10-15 2011-05-12 얀센 파마슈티카 엔.브이. 신경변성 질환 치료에 사용하는 카바메이트 화합물
PE20070325A1 (es) * 2005-06-29 2007-05-12 Alza Corp Formas de dosificacion oral que comprenden compuestos derivados de carbamato
US20070021500A1 (en) * 2005-07-12 2007-01-25 Twyman Roy E Methods for neuroprotection
US20070043120A1 (en) * 2005-08-18 2007-02-22 Bettina Beyreuther Therapeutic combination for painful medical conditions
ES2450070T5 (es) 2006-06-15 2018-05-08 Ucb Pharma Gmbh Composición farmacéutica que comprende lacosamida y levetiracetam con efecto anticonvulsionante sinérgico
WO2008045391A2 (en) * 2006-10-06 2008-04-17 Janssen Pharmaceutica Nv Novel crystal of (s)-(+)-2-(2-chlorophenyl)-2-hydroxy-ethyl carbamate
US20080103199A1 (en) * 2006-10-31 2008-05-01 Haas Magali Treatment of pervasive developmental disorders
US9018253B2 (en) 2010-07-02 2015-04-28 Bio-Pharm Solutions Co., Ltd. Phenylcarbamate compound and muscle relaxant containing the same
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
RU2632659C2 (ru) 2011-12-27 2017-10-09 Байо-Фарм Солюшнс Ко., Лтд. Фенилкарбаматные соединения для применения в предупреждении или лечении эпилепсии
CN105189451A (zh) * 2013-03-12 2015-12-23 比皮艾思药物研发有限公司 氨基甲酸苯酯化合物和包含该化合物的用于预防或治疗神经性毒气引起的疾病的组合物
WO2014142477A1 (en) * 2013-03-12 2014-09-18 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compounds for use in preventing or treating pediatric epilesy and epilesy-related syndromes
EP3423433A4 (en) * 2016-02-29 2019-12-25 Bio-Pharm Solutions Co., Ltd. SULFAMATE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE
CN106053510A (zh) * 2016-05-16 2016-10-26 山东省分析测试中心 一种基于氢核磁共振快速测定普瑞巴林原料药纯度的方法
KR102421006B1 (ko) * 2016-05-19 2022-07-14 에스케이바이오팜 주식회사 두통의 예방학적 치료를 위한 카바메이트 화합물의 용도

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
US20010034365A1 (en) * 1996-01-16 2001-10-25 Choi Yong Moon Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
US6104956A (en) * 1996-05-31 2000-08-15 Board Of Trustees Of Southern Illinois University Methods of treating traumatic brain injury by vagus nerve stimulation
WO2000047202A1 (en) * 1999-02-09 2000-08-17 University Of Virginia Patent Foundation Felbamate derived compounds
JP4951723B2 (ja) * 1999-07-26 2012-06-13 エスケー バイオファーマシューティカルズ カンパニー リミテッド 経鼻抗痙攣組成物及び調節方法
PL364680A1 (en) * 2001-02-27 2004-12-13 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating neurodegenerative disorders
ES2295320T3 (es) * 2001-02-27 2008-04-16 Ortho-Mcneil Pharmaceutical, Inc. Compuestos de carbamato utiles para prevenir o tratar el trastorno bipolar.
EP1408953B1 (en) * 2001-02-27 2006-04-26 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating bipolar disorder

Also Published As

Publication number Publication date
MX2007003278A (es) 2007-10-08
RS51269B (sr) 2010-12-31
WO2006033947A2 (en) 2006-03-30
HRP20100304T1 (hr) 2010-09-30
WO2006033947A3 (en) 2006-06-29
HK1105583A1 (en) 2008-02-22
US20110152362A1 (en) 2011-06-23
CN101056629A (zh) 2007-10-17
JP2008513466A (ja) 2008-05-01
NO20071921L (no) 2007-06-12
AU2005287174B2 (en) 2012-01-12
CR9053A (es) 2009-10-30
US20060194873A1 (en) 2006-08-31
CN101056629B (zh) 2012-01-11
AU2005287174A1 (en) 2006-03-30
BRPI0515374A (pt) 2008-07-22
NZ553813A (en) 2010-09-30
ATE464044T1 (de) 2010-04-15
KR20070057939A (ko) 2007-06-07
DE602005020667D1 (de) 2010-05-27
ES2342185T3 (es) 2010-07-02
IL181910A0 (en) 2007-07-04
EA200700642A1 (ru) 2007-10-26
PT1809273E (pt) 2010-05-10
CA2580640A1 (en) 2006-03-30
CO6382111A2 (es) 2012-02-15

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