EA017558B1 - ШТАММ БАКТЕРИЙ Е.Mundtii ST4SA, СПОСОБНЫЙ ПРОДУЦИРОВАТЬ АНТИБАКТЕРИАЛЬНЫЙ ПЕПТИД ST4SA, СПОСОБ ПОЛУЧЕНИЯ ПЕПТИДА ST4SA И ПРИМЕНЕНИЕ ШТАММА БАКТЕРИЙ Е.Mundtii ST4SA И ПЕПТИДА - Google Patents

ШТАММ БАКТЕРИЙ Е.Mundtii ST4SA, СПОСОБНЫЙ ПРОДУЦИРОВАТЬ АНТИБАКТЕРИАЛЬНЫЙ ПЕПТИД ST4SA, СПОСОБ ПОЛУЧЕНИЯ ПЕПТИДА ST4SA И ПРИМЕНЕНИЕ ШТАММА БАКТЕРИЙ Е.Mundtii ST4SA И ПЕПТИДА Download PDF

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EA017558B1
EA017558B1 EA200802409A EA200802409A EA017558B1 EA 017558 B1 EA017558 B1 EA 017558B1 EA 200802409 A EA200802409 A EA 200802409A EA 200802409 A EA200802409 A EA 200802409A EA 017558 B1 EA017558 B1 EA 017558B1
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Prior art keywords
peptide
strain
animal
st4sa
activity
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EA200802409A
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English (en)
Russian (ru)
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EA200802409A1 (ru
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Леон Милнер Теодоре Дикс
Светослав Димитров Тодоров
Хенриетте Кноетзе
Марелизе Бринк
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Сипла Медпро Ресеч Энд Девелопмент (Пти) Лтд.
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Priority claimed from ZA200604035A external-priority patent/ZA200604035B/xx
Application filed by Сипла Медпро Ресеч Энд Девелопмент (Пти) Лтд. filed Critical Сипла Медпро Ресеч Энд Девелопмент (Пти) Лтд.
Publication of EA200802409A1 publication Critical patent/EA200802409A1/ru
Publication of EA017558B1 publication Critical patent/EA017558B1/ru

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50Isolated enzymes; Isolated proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46Streptococcus ; Enterococcus; Lactococcus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Genetics & Genomics (AREA)
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  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA200802409A 2006-05-28 2007-05-25 ШТАММ БАКТЕРИЙ Е.Mundtii ST4SA, СПОСОБНЫЙ ПРОДУЦИРОВАТЬ АНТИБАКТЕРИАЛЬНЫЙ ПЕПТИД ST4SA, СПОСОБ ПОЛУЧЕНИЯ ПЕПТИДА ST4SA И ПРИМЕНЕНИЕ ШТАММА БАКТЕРИЙ Е.Mundtii ST4SA И ПЕПТИДА EA017558B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA200604035A ZA200604035B (en) 2005-05-31 2006-05-28 Improved grenade launcher
PCT/IB2007/051982 WO2007138538A2 (en) 2006-05-28 2007-05-25 Probiotic strain and antimicrobial peptide derived therefrom

Publications (2)

Publication Number Publication Date
EA200802409A1 EA200802409A1 (ru) 2009-10-30
EA017558B1 true EA017558B1 (ru) 2013-01-30

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EA200802409A EA017558B1 (ru) 2006-05-28 2007-05-25 ШТАММ БАКТЕРИЙ Е.Mundtii ST4SA, СПОСОБНЫЙ ПРОДУЦИРОВАТЬ АНТИБАКТЕРИАЛЬНЫЙ ПЕПТИД ST4SA, СПОСОБ ПОЛУЧЕНИЯ ПЕПТИДА ST4SA И ПРИМЕНЕНИЕ ШТАММА БАКТЕРИЙ Е.Mundtii ST4SA И ПЕПТИДА

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US (2) US7951385B2 (https=)
EP (1) EP2021457B1 (https=)
JP (1) JP2009538614A (https=)
KR (1) KR101521123B1 (https=)
CN (1) CN101454440B (https=)
AP (1) AP2841A (https=)
AU (1) AU2007266675B2 (https=)
CA (1) CA2647161A1 (https=)
EA (1) EA017558B1 (https=)
IL (2) IL195520A0 (https=)
NO (1) NO20084577L (https=)
NZ (1) NZ571619A (https=)
WO (1) WO2007138538A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101521123B1 (ko) * 2006-05-28 2015-05-19 시플라 메드프로 리서치 앤드 디벨롭먼트 (피티와이) 엘티디 프로바이오틱 스트레인 및 그로부터 유도된 항균 펩티드
US8357519B2 (en) * 2008-11-19 2013-01-22 The Ohio State University Methods and processes for producing esters
WO2011045764A1 (en) * 2009-10-15 2011-04-21 Cipla Medpro Research And Development (Pty) Ltd A product for delivering antimicrobially active substances to an infected site
JP5881017B2 (ja) * 2010-11-05 2016-03-09 国立大学法人広島大学 籾殻または玄米から単離された植物乳酸菌およびその利用
WO2012148891A1 (en) * 2011-04-29 2012-11-01 Evonik Degussa Corporation Peptide-lipid conjugates and uses thereof
RU2532227C1 (ru) * 2013-10-23 2014-10-27 Федеральное бюджетное учреждение науки Государственный научный центр прикладной микробиологии и биотехнологии (ФБУН ГНЦ ПМБ) Штамм enterоcoccus mundtii, продуцирующий субстанцию пептидной природы с антилистериозной активностью
RU2599430C1 (ru) * 2015-07-23 2016-10-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" ШТАММ ЛАКТОБАКТЕРИЙ Enterococcus mundtii - ПРОДУЦЕНТ МОЛОЧНОЙ КИСЛОТЫ И АНТИБИОТИЧЕСКИХ ВЕЩЕСТВ
US9944960B2 (en) * 2015-11-17 2018-04-17 Premier Research Labs, Lp Process for microbial production of dihydrolipoic acid and extraction of dihydrolipoic acid with edible oils
CN105385636A (zh) * 2015-12-07 2016-03-09 江南大学 一株产细菌素的肠膜明串珠菌及其应用
AU2017240064B8 (en) 2016-03-31 2021-11-11 Gojo Industries, Inc. Antimicrobial peptide stimulating sanitizing composition
EP3436041B1 (en) 2016-03-31 2023-05-24 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
WO2017173240A1 (en) 2016-03-31 2017-10-05 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
KR101722255B1 (ko) * 2016-04-22 2017-04-03 주식회사 폴인브레드 쌀과 쌀누룩을 이용한 자연발효종 제조방법
JP2020500860A (ja) 2016-11-23 2020-01-16 ゴジョ・インダストリーズ・インコーポレイテッド プロバイオティック/プレバイオティックな有効成分を含む消毒薬組成物
AU2018336988B2 (en) * 2017-09-19 2023-06-22 Advaxis, Inc. Compositions and methods for lyophilization of bacteria or Listeria strains
WO2019151371A1 (ja) * 2018-01-31 2019-08-08 ニュートリー株式会社 肺炎球菌感染症の予防及び/又は治療剤
KR102076089B1 (ko) 2018-10-02 2020-02-11 서울대학교 산학협력단 니신 z 생산능이 우수한 락토코커스 락티스 서브스페시스 락티스 ldtm 6804 신균주(kctc 13564bp)
CN109456911B (zh) * 2018-10-10 2019-10-18 南京林业大学 一株蒙氏肠球菌HcM7及其应用
CN110846260B (zh) * 2019-12-18 2021-03-02 江南大学 一株降低生物胺的肉葡萄球菌及其应用
KR102951826B1 (ko) * 2023-01-18 2026-04-13 조선대학교산학협력단 오리 유래 항균 펩타이드로부터 설계된 신규 항균 펩타이드 및 이의 용도

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003339377A (ja) * 2002-05-23 2003-12-02 Prima Meat Packers Ltd 新規バクテリオシン

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1084969A (ja) 1996-09-19 1998-04-07 Chemo Sero Therapeut Res Inst ヘモフィルス・パラガリナルム由来新規ポリペプチド及びその製法
US7655775B2 (en) * 1997-09-05 2010-02-02 Canbiocin, Inc. Expression vectors for treating bacterial infections
AU7898700A (en) 1999-10-22 2001-05-08 Shanghai Bio Road Gene Development Ltd. A novel polypeptide-rna binding protein 33 and polynucleotide encoding said polypeptide
GB0027761D0 (en) 2000-11-14 2000-12-27 Nestle Sa Nutritional composition for an immune condition
DE10105347A1 (de) * 2001-02-05 2002-08-22 Nutrinova Gmbh Sorbinsäurepräparat enthaltend Probiotika als Futtermittelzusatz in der Nutztieraufzucht
GB0125535D0 (en) 2001-10-24 2001-12-12 Microbiological Res Authority Mycobacterial genes down-regulated during latency
US6878373B2 (en) 2001-12-03 2005-04-12 Micropure Technologies, Inc. Probiotic composition containing Bacillus cereus RRRL B-30535
WO2004005492A2 (fr) * 2002-07-03 2004-01-15 Galina Gennadievna Alekhina Composition probiotique a base d'une souche d'enterocoques pour moyens de traitement et de prevention et procede de fabrication correspondant
EP1384483A1 (en) * 2002-07-23 2004-01-28 Nestec S.A. Probiotics for treatment of irritable bowel disease (IBS) through improvement of gut neuromuscular function
ITBO20020564A1 (it) 2002-09-06 2004-03-07 Alfa Wassermann Spa Bifidobatteri e preparazioni che li contengono.
KR101521123B1 (ko) * 2006-05-28 2015-05-19 시플라 메드프로 리서치 앤드 디벨롭먼트 (피티와이) 엘티디 프로바이오틱 스트레인 및 그로부터 유도된 항균 펩티드

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003339377A (ja) * 2002-05-23 2003-12-02 Prima Meat Packers Ltd 新規バクテリオシン

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DE KWAADSTENIET ET AL.: "Characterization of a 3944 Da bacteriocin, produced by Enterococcus mundtii ST15, with activity against Gram-positive and Gram-negative bacteria". INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 105, no. 3, 15 December, 2005 (2005-12-15), pages 433-444, XP005186610, ISSN: 0168-1605 *
KAWAMOTO SHINICHI ET AL.: "Biochemical and genetic characterization of mundticin KS, an antilisterial peptide produced by Enterococcus mundtii NFRI 7393". APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 68, no. 8, August 2002 (2002-08), pages 3830-3840, XP002465640, ISSN: 0099-2240, the whole document *
SAAVEDRA LUCILA ET AL.: "Enhancement of the enterocin CRL35 activity by a synthetic peptide derived from the NH2-terminal sequence". ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 48, no. 7, July 2004 (2004-07), pages 2778-2781, XP002465641, ISSN: 0066-4804, the whole document *
TODOROV S.D. ET AL.: "An antibacterial and antiviral peptide produced by Enterococcus mundtii ST4V isolated from soya beans". INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, AMSTERDAM, NL, vol. 25, no. 6, June 2005 (2005-06), pages 508-513, XP004911700, ISSN: 0924-8579 *
ZENDO T. ET AL.: "Identification and production of a bacteriocin from Enterococcus mundtii QU 2 isolated from soybean". JOURNAL OF APPLIED MICROBIOLOGY, vol. 99, no. 5, 2005, pages 1181-1190, XP002465642, ISSN: 1364-5072 *

Also Published As

Publication number Publication date
AU2007266675A1 (en) 2007-12-06
AU2007266675B2 (en) 2012-09-06
US20110268703A1 (en) 2011-11-03
AP2841A (en) 2014-02-28
AP2008004626A0 (en) 2008-10-31
US20090297482A1 (en) 2009-12-03
CA2647161A1 (en) 2007-12-06
US8444998B2 (en) 2013-05-21
NO20084577L (no) 2008-12-19
KR101521123B1 (ko) 2015-05-19
EP2021457B1 (en) 2015-02-11
NZ571619A (en) 2011-10-28
IL195520A0 (en) 2011-08-01
WO2007138538A3 (en) 2008-04-17
IL250634A0 (en) 2017-03-30
KR20090023626A (ko) 2009-03-05
EA200802409A1 (ru) 2009-10-30
CN101454440A (zh) 2009-06-10
US7951385B2 (en) 2011-05-31
WO2007138538A2 (en) 2007-12-06
EP2021457A2 (en) 2009-02-11
CN101454440B (zh) 2013-05-29
JP2009538614A (ja) 2009-11-12

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