EA016625B1 - Способ контроля прорывных кровотечений при пролонгированном режиме приема гормональных контрацептивов - Google Patents

Способ контроля прорывных кровотечений при пролонгированном режиме приема гормональных контрацептивов Download PDF

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Publication number
EA016625B1
EA016625B1 EA200601908A EA200601908A EA016625B1 EA 016625 B1 EA016625 B1 EA 016625B1 EA 200601908 A EA200601908 A EA 200601908A EA 200601908 A EA200601908 A EA 200601908A EA 016625 B1 EA016625 B1 EA 016625B1
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EA
Eurasian Patent Office
Prior art keywords
days
period
specified
break
oral contraceptive
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Application number
EA200601908A
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English (en)
Russian (ru)
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EA200601908A1 (ru
Inventor
Андреас Заксе
Original Assignee
Байер Фарма Акциенгезельшафт
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35056905&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA016625(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Байер Фарма Акциенгезельшафт filed Critical Байер Фарма Акциенгезельшафт
Publication of EA200601908A1 publication Critical patent/EA200601908A1/ru
Publication of EA016625B1 publication Critical patent/EA016625B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Steroid Compounds (AREA)
EA200601908A 2004-04-30 2005-04-29 Способ контроля прорывных кровотечений при пролонгированном режиме приема гормональных контрацептивов EA016625B1 (ru)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US56644304P 2004-04-30 2004-04-30
US57502404P 2004-05-28 2004-05-28
US57719904P 2004-06-07 2004-06-07
US63838004P 2004-12-27 2004-12-27
US66006805P 2005-03-10 2005-03-10
PCT/EP2005/004777 WO2005105103A2 (en) 2004-04-30 2005-04-29 Management of breakthrough bleeding in extended hormonal contraceptive regimens

Publications (2)

Publication Number Publication Date
EA200601908A1 EA200601908A1 (ru) 2007-04-27
EA016625B1 true EA016625B1 (ru) 2012-06-29

Family

ID=35056905

Family Applications (2)

Application Number Title Priority Date Filing Date
EA200601908A EA016625B1 (ru) 2004-04-30 2005-04-29 Способ контроля прорывных кровотечений при пролонгированном режиме приема гормональных контрацептивов
EA201200377A EA031227B1 (ru) 2004-04-30 2005-04-29 Способ пероральной контрацепции у женщин, способ профилактики нежелательных кровотечений в течение пероральной контрацепции у женщин и фармацевтический набор для применения в этих способах

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA201200377A EA031227B1 (ru) 2004-04-30 2005-04-29 Способ пероральной контрацепции у женщин, способ профилактики нежелательных кровотечений в течение пероральной контрацепции у женщин и фармацевтический набор для применения в этих способах

Country Status (29)

Country Link
US (3) US8163721B2 (enExample)
EP (1) EP1747001B1 (enExample)
JP (4) JP2007535519A (enExample)
KR (4) KR20070004919A (enExample)
CN (1) CN103127156A (enExample)
AR (1) AR048722A1 (enExample)
AU (1) AU2005237255B2 (enExample)
BR (1) BRPI0510493A (enExample)
CA (1) CA2562296A1 (enExample)
CR (1) CR8709A (enExample)
DK (1) DK1747001T3 (enExample)
EA (2) EA016625B1 (enExample)
EC (1) ECSP066999A (enExample)
ES (1) ES2704999T3 (enExample)
HU (1) HUE041475T2 (enExample)
IL (1) IL178458A (enExample)
LT (1) LT1747001T (enExample)
MX (1) MXPA06012567A (enExample)
MY (1) MY151322A (enExample)
NO (1) NO341685B1 (enExample)
NZ (1) NZ586107A (enExample)
PA (1) PA8631801A1 (enExample)
PE (1) PE20060467A1 (enExample)
SG (2) SG152288A1 (enExample)
SI (1) SI1747001T1 (enExample)
SV (1) SV2006002100A (enExample)
TW (1) TWI374735B (enExample)
UY (1) UY28875A1 (enExample)
WO (1) WO2005105103A2 (enExample)

Families Citing this family (27)

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Publication number Priority date Publication date Assignee Title
US20020132801A1 (en) * 2001-01-11 2002-09-19 Schering Aktiengesellschaft Drospirenone for hormone replacement therapy
MY151322A (en) * 2004-04-30 2014-05-15 Bayer Ip Gmbh Management of breakthrough bleeding in extended hormonal contraceptive regimens
US20070111975A1 (en) 2004-10-07 2007-05-17 Duramed Pharmaceuticals, Inc. Methods of Hormonal Treatment Utilizing Ascending-Dose Extended Cycle Regimens
US20070088010A1 (en) * 2005-10-17 2007-04-19 Doris Huebler Method of making a single-stage pharmaceutical preparation for oral therapy of dysfunctional uterine bleeding, containing ethinyl estradiol and dienogest
EP1977752A1 (de) * 2007-03-01 2008-10-08 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Zubereitung zur Verminderung der Endometriose
DE102007011105A1 (de) * 2007-03-02 2008-09-04 Bayer Schering Pharma Aktiengesellschaft Mineralcorticoid-Rezeptor-Antagonisten zur Behandlung von Endometriose
WO2010033188A2 (en) * 2008-09-16 2010-03-25 Playtex Products, Llc. Dosages for menstrual suppression, contraception, and hormone replacement therapy, and methods of administering same
EP2343963B1 (en) 2008-10-08 2019-04-10 Agile Therapeutics, Inc. Transdermal delivery
US9198919B2 (en) 2008-10-08 2015-12-01 Agile Therapeutics, Inc. Contraceptive transdermal delivery of hormones
US9192614B2 (en) 2008-10-08 2015-11-24 Agile Therapeutics, Inc. Contraceptive transdermal delivery of hormones
WO2010111488A1 (en) 2009-03-27 2010-09-30 Agile Therapeutics, Inc. Transdermal delivery
AR081670A1 (es) 2010-06-29 2012-10-10 Leon Farma Sa Lab Composicion farmaceutica que comprende drospirenona y kit anticonceptivo
US10849857B2 (en) 2010-07-28 2020-12-01 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
US11351122B1 (en) 2010-07-28 2022-06-07 Laboratorios Leon Farma Sa Synthetic progestogens and pharmaceutical compositions comprising the same
US9603860B2 (en) 2010-07-28 2017-03-28 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
ES2877186T3 (es) 2015-06-18 2021-11-16 Estetra Sprl Comprimido orodispersable que contiene estetrol
US11147771B2 (en) 2015-06-18 2021-10-19 Estetra Sprl Orodispersible dosage unit containing an estetrol component
CN116077454A (zh) 2015-06-18 2023-05-09 埃斯特拉有限责任公司 含雌四醇组分的口腔分散剂量单位
JP6813150B2 (ja) 2015-06-18 2021-01-13 エステトラ ソシエテ プリーヴ ア レスポンサビリテ リミテ エステトロールを含有する口腔内崩壊錠
HUE065350T2 (hu) * 2015-06-23 2024-05-28 Laboratorios Leon Farma Sa Drospirenonalapú fogamzásgátló túlsúllyal érintett nõi beteg számára
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
MD3518933T4 (ro) 2016-09-30 2025-10-31 Myovant Sciences Gmbh Metode de tratare a fibromului uterin și a endometriozei
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物
US12138270B2 (en) 2021-09-07 2024-11-12 Millicent Pharma Limited Contraceptive regimen including reduced level of estrogen

Citations (7)

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Publication number Priority date Publication date Assignee Title
WO1998004269A1 (en) * 1996-07-26 1998-02-05 American Home Products Corporation Monophasic contraceptive method and kit comprising a combination of a progestin and estrogen
EP0911029A2 (en) * 1997-06-23 1999-04-28 Medical College Of Hampton Roads Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy
WO2002022110A2 (en) * 2000-09-14 2002-03-21 Schering Aktiengesellschaft Contraception process and administration form for the same
USRE37838E1 (en) * 1993-12-22 2002-09-10 Schering Aktiengesellschaft Composition for contraception
US6451778B1 (en) * 1996-07-26 2002-09-17 Wyeth Oral contraceptive
US6500814B1 (en) * 1997-09-11 2002-12-31 Wyeth Pharmaceuticals Hormonal contraceptive
US20030119798A1 (en) * 1999-08-31 2003-06-26 Schering Aktiengesellschaft Pharmaceutical composition for use as a contraceptive

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US5244096A (en) 1988-04-22 1993-09-14 Stoner Fred L Preventive treatment kit against sexually transmitted disease
WO1993013801A1 (en) 1992-01-17 1993-07-22 The Procter & Gamble Company Treatment for atherosclerosis
US5552394A (en) 1994-07-22 1996-09-03 The Medical College Of Hampton Roads Low dose oral contraceptives with less breakthrough bleeding and sustained efficacy
US5842441A (en) 1996-08-26 1998-12-01 Pharmalett Denmark A/S Medicated and individualized treatment shampoo for dermatological disturbances of companion animals
DE60042089D1 (de) * 1999-08-31 2009-06-04 Bayer Schering Pharma Ag Pharmazeutische Kombination von Ethinylestradiol und Drospirenon als empfängnisverhütendes Mittel
CO5271709A1 (es) 2000-01-12 2003-04-30 Pfizer Prod Inc Composiciones y procedimientos para el y tratamiento de afecciones que responden a estrogenos
US6653298B2 (en) * 2000-01-14 2003-11-25 Sterix Limited Composition
IL145876A0 (en) 2000-10-17 2002-07-25 Pfizer Prod Inc Methods and kits for improving vascular health
US20020193356A1 (en) * 2001-05-23 2002-12-19 Van Beek Agatha Antonia Magdalena Means and method for hormonal contraception
US20030018018A1 (en) 2001-07-10 2003-01-23 Medical College Of Hampton Roads Ultra low dose oral contraceptives with sustained efficacy and induced amenorrhea
MY151322A (en) 2004-04-30 2014-05-15 Bayer Ip Gmbh Management of breakthrough bleeding in extended hormonal contraceptive regimens
US8501720B2 (en) 2004-07-30 2013-08-06 Bayer Pharma AG Method for treatment of dysmenorrhea

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USRE37838E1 (en) * 1993-12-22 2002-09-10 Schering Aktiengesellschaft Composition for contraception
WO1998004269A1 (en) * 1996-07-26 1998-02-05 American Home Products Corporation Monophasic contraceptive method and kit comprising a combination of a progestin and estrogen
US6451778B1 (en) * 1996-07-26 2002-09-17 Wyeth Oral contraceptive
EP0911029A2 (en) * 1997-06-23 1999-04-28 Medical College Of Hampton Roads Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy
US6500814B1 (en) * 1997-09-11 2002-12-31 Wyeth Pharmaceuticals Hormonal contraceptive
US20030119798A1 (en) * 1999-08-31 2003-06-26 Schering Aktiengesellschaft Pharmaceutical composition for use as a contraceptive
WO2002022110A2 (en) * 2000-09-14 2002-03-21 Schering Aktiengesellschaft Contraception process and administration form for the same

Non-Patent Citations (5)

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Title
BIRKHAEUSER M. ET AL.: "EMPFEHLUNGEN ZUR HORMONALEN KONTRAZEPTION". FRAUENARZT, PUBLIMED, MED. U. MEDIEN DEUTSCHE GESELLSCHAFT F}R GYN{KOLOGIE, DE, vol. 44, no. 12, 2003, pages 1270-1273, XP009055739, ISSN: 0016-0237, the whole document *
JENAPHARM: "NEUES PERIODENSYSTEM MIT VALETTE". JENAPHARM, March 2004 (2004-03), XP002350231, the whole document *
ROSENBERG ET AL.: "Causes and consequences of oral contraceptive noncompliance". AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY, MOSBY, ST LOUIS, MO, US, vol. 180, no. 2, February 1999 (1999-02), pages S276-S279, XP005179066, ISSN: 0002-9378, the whole document *
SILLEM M. ET AL.: "Use of an oral contraceptive containing drospirenone in an extended regimen". THE EUROPEAN JOURNAL OF CONTRACEPTION & REPRODUCTIVE HEALTH CARE: THE OFFICIAL JOURNAL OF THE EUROPEAN SOCIETY OF CONTRACEPTION. SEP 2003, vol. 8, no. 3, September 2003 (2003-09), pages 162-169, XP008064769, ISSN: 1362-5187, abstract, page 163, paragraph 3, page 165, paragraphs 1, 2, page 167, column 2, paragraph 3 - page 168, column 2, paragraph 2 *
WIEGRATZ I. ET AL.: "Attitude of German women and gynecologists towards long-cycle treatment with oral contraceptives". CONTRACEPTION, GERON-X, INC., LOS ALTOS, CA, US, vol. 69, no. 1, January 2004 (2004-01), pages 37-42, XP002353728, ISSN: 0010-7824, the whole document *

Also Published As

Publication number Publication date
NO341685B1 (no) 2017-12-18
EA200601908A1 (ru) 2007-04-27
ES2704999T3 (es) 2019-03-21
ECSP066999A (es) 2006-12-29
KR20150058555A (ko) 2015-05-28
EA201200377A1 (ru) 2012-08-30
JP2007535519A (ja) 2007-12-06
EA201200377A8 (ru) 2018-01-31
WO2005105103A2 (en) 2005-11-10
HUE041475T2 (hu) 2019-05-28
US8163721B2 (en) 2012-04-24
MXPA06012567A (es) 2006-12-15
JP2015187157A (ja) 2015-10-29
MY151322A (en) 2014-05-15
KR20130022425A (ko) 2013-03-06
TWI374735B (en) 2012-10-21
CN103127156A (zh) 2013-06-05
DK1747001T3 (en) 2019-02-04
JP2017048253A (ja) 2017-03-09
SV2006002100A (es) 2006-02-15
JP6134491B2 (ja) 2017-05-24
JP6153967B2 (ja) 2017-06-28
SI1747001T1 (sl) 2019-02-28
AU2005237255B2 (en) 2011-07-07
EP1747001A2 (en) 2007-01-31
PE20060467A1 (es) 2006-06-11
US20150174142A1 (en) 2015-06-25
JP2013018787A (ja) 2013-01-31
US20120202779A1 (en) 2012-08-09
CR8709A (es) 2007-08-28
NO20065499L (no) 2006-11-29
NZ586107A (en) 2012-05-25
IL178458A (en) 2016-08-31
EP1747001B1 (en) 2018-10-10
LT1747001T (lt) 2019-01-25
KR20160150113A (ko) 2016-12-28
US20050250747A1 (en) 2005-11-10
KR101812160B1 (ko) 2017-12-27
BRPI0510493A (pt) 2007-11-13
PA8631801A1 (es) 2006-11-09
WO2005105103A3 (en) 2006-09-08
IL178458A0 (en) 2008-04-13
TW200603781A (en) 2006-02-01
KR20070004919A (ko) 2007-01-09
CA2562296A1 (en) 2005-11-10
AR048722A1 (es) 2006-05-17
SG10201701904TA (en) 2017-05-30
EA031227B1 (ru) 2018-12-28
AU2005237255A1 (en) 2005-11-10
UY28875A1 (es) 2005-11-30
SG152288A1 (en) 2009-05-29

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