EA013371B1 - Новые соединения, содержащие их фармацевтические композиции и способы их применения - Google Patents
Новые соединения, содержащие их фармацевтические композиции и способы их применения Download PDFInfo
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- EA013371B1 EA013371B1 EA200500178A EA200500178A EA013371B1 EA 013371 B1 EA013371 B1 EA 013371B1 EA 200500178 A EA200500178 A EA 200500178A EA 200500178 A EA200500178 A EA 200500178A EA 013371 B1 EA013371 B1 EA 013371B1
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- Eurasian Patent Office
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- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39458502P | 2002-07-09 | 2002-07-09 | |
| PCT/US2003/021700 WO2004005277A1 (en) | 2002-07-09 | 2003-07-09 | Novel compunds, pharmaceutical compositions containing same, and methods of use for same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200500178A1 EA200500178A1 (ru) | 2006-02-24 |
| EA013371B1 true EA013371B1 (ru) | 2010-04-30 |
Family
ID=30115739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200500178A EA013371B1 (ru) | 2002-07-09 | 2003-07-09 | Новые соединения, содержащие их фармацевтические композиции и способы их применения |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7649012B2 (OSRAM) |
| EP (3) | EP1539730A4 (OSRAM) |
| JP (3) | JP2005533835A (OSRAM) |
| KR (1) | KR101087559B1 (OSRAM) |
| CN (2) | CN101602756B (OSRAM) |
| AU (1) | AU2003265267B2 (OSRAM) |
| BR (1) | BRPI0312649A2 (OSRAM) |
| CA (2) | CA2767092C (OSRAM) |
| EA (1) | EA013371B1 (OSRAM) |
| IL (2) | IL166108A0 (OSRAM) |
| MX (1) | MXPA05000365A (OSRAM) |
| SG (1) | SG169236A1 (OSRAM) |
| WO (1) | WO2004005277A1 (OSRAM) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04007556A (es) | 2002-02-08 | 2005-12-05 | Univ Johns Hopkins Med | Estimulacion de cpt-1 como medio para reducir peso. |
| WO2004005277A1 (en) * | 2002-07-09 | 2004-01-15 | Fasgen, Inc. | Novel compunds, pharmaceutical compositions containing same, and methods of use for same |
| JP4493494B2 (ja) * | 2002-07-09 | 2010-06-30 | ファスゲン，インク． | ヒトおよび動物における微生物感染症の治療方法 |
| BRPI0510397A (pt) * | 2004-05-26 | 2007-11-13 | Fasgen Llc | compostos, composições farmacêuticas contendo os mesmos, e métodos de uso dos mesmos |
| BRPI0715160A2 (pt) | 2006-08-08 | 2013-06-11 | Sanofi Aventis | imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso |
| KR20090098804A (ko) * | 2006-11-08 | 2009-09-17 | 파스젠, 엘엘씨. | 신규한 화합물, 이를 함유하는 약제학적 조성물 및 이의 사용 방법 |
| WO2008059214A1 (en) * | 2006-11-13 | 2008-05-22 | Astrazeneca Ab | Bisamlde derivatives and use thereof as fatty acid synthase inhibitors |
| CN102111998A (zh) * | 2008-06-02 | 2011-06-29 | 法斯根公司 | 新化合物，含有它们的药物组合物及其使用方法 |
| US8470841B2 (en) | 2008-07-09 | 2013-06-25 | Sanofi | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
| WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
| WO2010118324A2 (en) | 2009-04-09 | 2010-10-14 | Nuclea Biotechnologies, LLC | Antibodies against fatty acid synthase |
| US9149445B2 (en) | 2009-07-27 | 2015-10-06 | The Trustees Of Princeton University | Inhibition of glycerol-3-phosphate acyltransferase (GPAT) and associated enzymes for treatment of viral infections |
| ES2443016T3 (es) | 2009-08-26 | 2014-02-17 | Sanofi | Nuevos hidratos cristalinos de fluoroglicósidos heteroaromáticos, productos farmacéuticos que comprenden estos compuestos, y su empleo |
| US8450350B2 (en) | 2010-05-05 | 2013-05-28 | Infinity Pharmaceuticals, Inc. | Triazoles as inhibitors of fatty acid synthase |
| EP3159331A1 (en) | 2010-05-05 | 2017-04-26 | Infinity Pharmaceuticals, Inc. | Tetrazolones as inhibitors of fatty acid synthase |
| WO2012120050A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683703B1 (de) | 2011-03-08 | 2015-05-27 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683701B1 (de) | 2011-03-08 | 2014-12-24 | Sanofi | Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8710050B2 (en) | 2011-03-08 | 2014-04-29 | Sanofi | Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US8809325B2 (en) | 2011-03-08 | 2014-08-19 | Sanofi | Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof |
| EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012135027A2 (en) * | 2011-03-25 | 2012-10-04 | The Research Foundation Of State University Of New York | Thiolactone antibiotics |
| EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| JP6228198B2 (ja) | 2012-06-25 | 2017-11-08 | トーマス・ジェファーソン・ユニバーシティＴｈｏｍａｓ Ｊｅｆｆｅｒｓｏｎ Ｕｎｉｖｅｒｓｉｔｙ | 異常な脂質生合成シグナル伝達を有するがんを処置するための組成物および方法 |
| EP2892892B1 (en) * | 2012-09-07 | 2017-05-31 | Janssen Pharmaceutica NV | Imidazolin-5-one derivatives useful as fatty acid synthase (fasn) inhibitors for the treatment of cancer |
| SG11201507486SA (en) | 2013-03-13 | 2015-10-29 | Forma Therapeutics Inc | Novel compounds and compositions for inhibition of fasn |
| WO2016079317A1 (en) | 2014-11-20 | 2016-05-26 | Vib Vzw | Means and methods for treatment of early-onset parkinson's disease |
| CN113382633A (zh) | 2018-10-29 | 2021-09-10 | 福马治疗股份有限公司 | (4-(2-氟-4-(1-甲基-1H-苯并[d]咪唑-5-基)苯甲酰基)哌嗪-1-基)(1-羟基环丙基)甲酮的固体形式 |
| CN114480521B (zh) * | 2020-11-13 | 2024-07-26 | 中国科学院青岛生物能源与过程研究所 | 一种三氮菌素c的制备方法 |
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| SU1512481A3 (ru) * | 1986-09-24 | 1989-09-30 | Лонца Аг (Фирма) | Способ получени тиотетроновой кислоты |
| US6376682B1 (en) * | 2000-02-01 | 2002-04-23 | Takama System, Ltd. | Compound with α-glucosidase inhibiting action and method for producing the same |
| US6380214B1 (en) * | 1999-05-19 | 2002-04-30 | Pfizer Inc. | Heterocyclic derivatives useful as anticancer agents |
| US6391912B1 (en) * | 1996-12-12 | 2002-05-21 | Bayer Aktiengesellschaft | Substituted phenylketoenols |
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| US3496187A (en) * | 1967-03-20 | 1970-02-17 | American Home Prod | N-(heterocyclyl)aconamides |
| US3472878A (en) * | 1969-01-27 | 1969-10-14 | American Home Prod | N-(hydroxyaryl)aconamides |
| JPS5859920A (ja) * | 1981-10-05 | 1983-04-09 | Chugai Pharmaceut Co Ltd | 生体防禦能賦活剤 |
| US4565699A (en) * | 1983-07-18 | 1986-01-21 | The Upjohn Company | Composition of matter and process |
| US4720503A (en) * | 1985-08-02 | 1988-01-19 | Merck & Co., Inc. | N-substituted fused-heterocyclic carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors |
| US4753871A (en) * | 1986-12-12 | 1988-06-28 | Eastman Kodak Company | Cyan dye-forming couplers and photographic materials containing same |
| WO1988004652A1 (fr) * | 1986-12-17 | 1988-06-30 | Nippon Soda Co., Ltd. | Composes heterocycliques possedant un squelette triketo |
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| US5614551A (en) | 1994-01-24 | 1997-03-25 | The Johns Hopkins University | Inhibitors of fatty acid synthesis as antimicrobial agents |
| BR9608229A (pt) * | 1995-05-09 | 1998-12-29 | Bayer Ag | Cetoenóis alquil-dihalogenofenil-substituídos |
| US5981575A (en) | 1996-11-15 | 1999-11-09 | Johns Hopkins University, The | Inhibition of fatty acid synthase as a means to reduce adipocyte mass |
| JPH10212284A (ja) * | 1996-11-27 | 1998-08-11 | Sagami Chem Res Center | テトロン酸−３−カルボン酸誘導体、その製造方法、製造中間体、抗がん剤、及び蛋白脱リン酸化酵素阻害剤 |
| CO4970714A1 (es) * | 1997-09-05 | 2000-11-07 | Boehringer Mannheim Gmbh | Derivados ureido y tioureido de 4-amino-2(5h)-furanonas y 4-amino-2(5h) tiofenonas como agentes antitumorales |
| IT1315267B1 (it) * | 1999-12-23 | 2003-02-03 | Novuspharma Spa | Derivati di 2-(1h-indol-3-il)-2-oxo-acetammidi ad attivita'antitumorale |
| GB0000131D0 (en) * | 2000-01-06 | 2000-02-23 | Univ Cardiff | Thiolactomycin analogues,compositions containing the same and uses thereof |
| JP2004528341A (ja) | 2001-05-02 | 2004-09-16 | ニューヨーク・ユニバーシティ | 脂肪酸合成酵素の阻害による色素形成の阻害 |
| MXPA04007556A (es) * | 2002-02-08 | 2005-12-05 | Univ Johns Hopkins Med | Estimulacion de cpt-1 como medio para reducir peso. |
| WO2004005277A1 (en) * | 2002-07-09 | 2004-01-15 | Fasgen, Inc. | Novel compunds, pharmaceutical compositions containing same, and methods of use for same |
| JP4493494B2 (ja) | 2002-07-09 | 2010-06-30 | ファスゲン，インク． | ヒトおよび動物における微生物感染症の治療方法 |
| US9690894B1 (en) | 2015-11-02 | 2017-06-27 | Altera Corporation | Safety features for high level design |
-
2003
- 2003-07-09 WO PCT/US2003/021700 patent/WO2004005277A1/en not_active Ceased
- 2003-07-09 EA EA200500178A patent/EA013371B1/ru not_active IP Right Cessation
- 2003-07-09 JP JP2004520132A patent/JP2005533835A/ja active Pending
- 2003-07-09 CN CN200910203849.8A patent/CN101602756B/zh not_active Expired - Fee Related
- 2003-07-09 EP EP03763470A patent/EP1539730A4/en not_active Withdrawn
- 2003-07-09 KR KR1020057000382A patent/KR101087559B1/ko not_active Expired - Fee Related
- 2003-07-09 CA CA2767092A patent/CA2767092C/en not_active Expired - Fee Related
- 2003-07-09 CA CA2491802A patent/CA2491802C/en not_active Expired - Fee Related
- 2003-07-09 EP EP11164126A patent/EP2386551A1/en not_active Withdrawn
- 2003-07-09 AU AU2003265267A patent/AU2003265267B2/en not_active Ceased
- 2003-07-09 SG SG200806632-6A patent/SG169236A1/en unknown
- 2003-07-09 US US10/520,505 patent/US7649012B2/en not_active Expired - Fee Related
- 2003-07-09 CN CNB038185563A patent/CN100513404C/zh not_active Expired - Fee Related
- 2003-07-09 MX MXPA05000365A patent/MXPA05000365A/es active IP Right Grant
- 2003-07-09 BR BRPI0312649A patent/BRPI0312649A2/pt not_active IP Right Cessation
- 2003-07-09 EP EP11164123A patent/EP2386550A1/en not_active Withdrawn
-
2005
- 2005-01-03 IL IL16610805A patent/IL166108A0/xx unknown
-
2008
- 2008-03-17 IL IL190218A patent/IL190218A0/en unknown
-
2010
- 2010-01-13 US US12/686,691 patent/US20100120901A1/en not_active Abandoned
- 2010-10-08 JP JP2010228956A patent/JP2011037881A/ja active Pending
-
2013
- 2013-06-04 JP JP2013117677A patent/JP2013189464A/ja active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| SU1512481A3 (ru) * | 1986-09-24 | 1989-09-30 | Лонца Аг (Фирма) | Способ получени тиотетроновой кислоты |
| US6391912B1 (en) * | 1996-12-12 | 2002-05-21 | Bayer Aktiengesellschaft | Substituted phenylketoenols |
| US6380214B1 (en) * | 1999-05-19 | 2002-04-30 | Pfizer Inc. | Heterocyclic derivatives useful as anticancer agents |
| US6376682B1 (en) * | 2000-02-01 | 2002-04-23 | Takama System, Ltd. | Compound with α-glucosidase inhibiting action and method for producing the same |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003265267B2 (en) | 2010-03-11 |
| BRPI0312649A2 (pt) | 2017-05-16 |
| EP2386550A1 (en) | 2011-11-16 |
| IL190218A0 (en) | 2008-11-03 |
| JP2011037881A (ja) | 2011-02-24 |
| CN101602756A (zh) | 2009-12-16 |
| US7649012B2 (en) | 2010-01-19 |
| IL166108A0 (en) | 2006-01-15 |
| CA2491802C (en) | 2012-04-10 |
| EP2386551A1 (en) | 2011-11-16 |
| EP1539730A1 (en) | 2005-06-15 |
| HK1083835A1 (zh) | 2006-07-14 |
| CA2767092A1 (en) | 2004-01-15 |
| US20060247302A1 (en) | 2006-11-02 |
| AU2003265267A1 (en) | 2004-01-23 |
| CN1675192A (zh) | 2005-09-28 |
| KR101087559B1 (ko) | 2011-11-29 |
| CN101602756B (zh) | 2014-11-12 |
| WO2004005277A1 (en) | 2004-01-15 |
| SG169236A1 (en) | 2011-03-30 |
| CA2767092C (en) | 2013-10-15 |
| CN100513404C (zh) | 2009-07-15 |
| EA200500178A1 (ru) | 2006-02-24 |
| JP2005533835A (ja) | 2005-11-10 |
| CA2491802A1 (en) | 2004-01-15 |
| US20100120901A1 (en) | 2010-05-13 |
| MXPA05000365A (es) | 2005-09-20 |
| JP2013189464A (ja) | 2013-09-26 |
| EP1539730A4 (en) | 2007-03-28 |
| KR20060002007A (ko) | 2006-01-06 |
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| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
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