EA003696B1 - Селективный в отношении цог-2 карпрофен для лечения боли и воспаления у собак - Google Patents

Селективный в отношении цог-2 карпрофен для лечения боли и воспаления у собак Download PDF

Info

Publication number
EA003696B1
EA003696B1 EA199900895A EA199900895A EA003696B1 EA 003696 B1 EA003696 B1 EA 003696B1 EA 199900895 A EA199900895 A EA 199900895A EA 199900895 A EA199900895 A EA 199900895A EA 003696 B1 EA003696 B1 EA 003696B1
Authority
EA
Eurasian Patent Office
Prior art keywords
cox
carprofen
inflammatory
inhibition
inhibitors
Prior art date
Application number
EA199900895A
Other languages
English (en)
Russian (ru)
Other versions
EA199900895A1 (ru
Inventor
Кристин Мэри Ланди
Энтони Пол Рикеттс
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of EA199900895A1 publication Critical patent/EA199900895A1/ru
Publication of EA003696B1 publication Critical patent/EA003696B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
EA199900895A 1997-05-05 1998-05-01 Селективный в отношении цог-2 карпрофен для лечения боли и воспаления у собак EA003696B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4563597P 1997-05-05 1997-05-05
PCT/IB1998/000662 WO1998050033A1 (fr) 1997-05-05 1998-05-01 Carprofene inhibant selectivement cox-2 et utilise dans le traitement de la douleur et des inflammations chez les chiens

Publications (2)

Publication Number Publication Date
EA199900895A1 EA199900895A1 (ru) 2000-06-26
EA003696B1 true EA003696B1 (ru) 2003-08-28

Family

ID=21939053

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900895A EA003696B1 (ru) 1997-05-05 1998-05-01 Селективный в отношении цог-2 карпрофен для лечения боли и воспаления у собак

Country Status (32)

Country Link
EP (1) EP0988034A1 (fr)
JP (1) JP2000513020A (fr)
KR (2) KR20040004406A (fr)
CN (1) CN1255059A (fr)
AP (1) AP9801234A0 (fr)
AR (2) AR011726A1 (fr)
AU (1) AU6932198A (fr)
BG (1) BG103852A (fr)
BR (1) BR9808720A (fr)
CA (1) CA2288759A1 (fr)
DZ (1) DZ2479A1 (fr)
EA (1) EA003696B1 (fr)
GT (1) GT199800063A (fr)
HR (1) HRP980244A2 (fr)
HU (1) HUP0001286A3 (fr)
ID (1) ID21311A (fr)
IL (1) IL132570A0 (fr)
IS (1) IS5220A (fr)
MA (1) MA26491A1 (fr)
NO (1) NO995389L (fr)
NZ (1) NZ500183A (fr)
OA (1) OA11213A (fr)
PA (1) PA8450601A1 (fr)
PE (1) PE72599A1 (fr)
PL (1) PL337003A1 (fr)
SK (1) SK148199A3 (fr)
TN (1) TNSN98059A1 (fr)
TW (1) TW590773B (fr)
UY (1) UY24989A1 (fr)
WO (1) WO1998050033A1 (fr)
YU (1) YU55899A (fr)
ZA (1) ZA983722B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2816016C1 (ru) * 2020-11-30 2024-03-25 Инново Терапьютикс Инк. Фармацевтическая композиция для предупрежденияили лечения раны или рубца, включающая бензбромарон

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245797B1 (en) 1997-10-22 2001-06-12 Merck & Co., Inc. Combination therapy for reducing the risks associated with cardio-and-cerebrovascular disease
AU2003204888B2 (en) * 1998-05-22 2005-07-28 Pfizer Products Inc. Treating or Preventing the Early Stages of Degeneration of Articular Cartilage or Subchondral Bone in Mammals Using Carprofen and Derivatives
US6506785B2 (en) 1998-05-22 2003-01-14 Pfizer, Inc. Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives
AU764872B2 (en) * 1998-10-23 2003-09-04 Merck Frosst Canada & Co. Combination product comprising an E-type prostaglandin ligand and a cox-2 selective inhibitor and methods of use
WO2000053149A2 (fr) * 1999-03-10 2000-09-14 G.D. Searle & Co. Procede et composition se rapportant a l'administration d'un inhibiteur de la cyclo-oxygenase-2
WO2001034204A1 (fr) * 1999-11-11 2001-05-17 Eli Lilly And Company Produits composes oncolytiques destines au traitement du cancer
JP2004521856A (ja) * 2000-05-15 2004-07-22 メルク フロスト カナダ アンド カンパニー Ｃｏｘ−２選択的阻害剤およびトロンボキサン阻害剤を用いる併用療法ならびにそのための組成物
RU2003100874A (ru) 2000-06-13 2004-06-27 Вайс (Us) Болеутоляющие и противовоспалительные составы, содержащие ингибиторы циклооксигеназы-2
DE10032132A1 (de) * 2000-07-01 2002-01-17 Lohmann Therapie Syst Lts Dermales Therapeutisches System enthaltend nichtsteroidale Antiphlogistika mit selektiver COX-2-Hemmung
US7189504B2 (en) 2000-08-07 2007-03-13 Vanderbilt University Compositions and methods for detecting and quantifying COX-2 activity and 2-arachidonylglycerol metabolites
US20040209959A1 (en) * 2001-07-16 2004-10-21 Edward Hogestatt Congeners of acetaminophen and related compounds as substrates for fatty acid conjugation and their use in treatment of pain, fever and inflammation
CA2519189C (fr) 2003-05-07 2012-07-17 Osteologix A/S Sels de strontium solubles dans l'eau pour le traitement de maladies des cartilages et/ou des os
KR100780983B1 (ko) * 2003-07-31 2007-11-30 파마시아 앤드 업존 캄파니 엘엘씨 소염제의 분산성 제제
WO2006123247A2 (fr) * 2005-05-20 2006-11-23 Pfizer Limited Combinaisons synergiques
WO2008122967A2 (fr) 2007-04-04 2008-10-16 Sigmoid Pharma Limited Composition pharmaceutique orale
WO2008132707A1 (fr) 2007-04-26 2008-11-06 Sigmoid Pharma Limited Fabrication de minicapsules multiples
US9278070B2 (en) 2009-05-18 2016-03-08 Sigmoid Pharma Limited Composition comprising oil drops
EP2464341B1 (fr) 2009-08-12 2022-07-06 Sublimity Therapeutics Limited Compositions immunomodulatrices comprenant une matrice polymère et une phase huileuse
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
DK3113774T3 (da) 2014-03-06 2022-03-07 Elanco Animal Health Incorporated Sammensætninger af grapiprant og fremgangsmåder til anvendelse deraf
EA036036B1 (ru) 2014-11-07 2020-09-16 Сигмойд Фарма Лимитед Композиции, содержащие циклоспорин
US12109218B2 (en) 2014-12-09 2024-10-08 Aratana Therapeutics, Inc. Compositions of grapiprant and methods for using the same
MX2017009011A (es) * 2015-01-09 2017-10-02 Jaguar Animal Health Metodos para tratar la diarrea en animales de compañia.
JP2023520367A (ja) * 2020-03-25 2023-05-17 エスアールアイ インターナショナル リポキシゲナーゼ阻害剤
US11116737B1 (en) 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections
KR102404883B1 (ko) 2020-11-30 2022-06-07 (주)이노보테라퓨틱스 벤즈브로마론을 포함하는 켈로이드 또는 비대흉터 예방 또는 치료용 약학 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3896145A (en) * 1972-07-24 1975-07-22 Hoffmann La Roche Carbazoles
CA1319886C (fr) * 1987-02-03 1993-07-06 Alberto Ferro Solutions de micelles mixtes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2816016C1 (ru) * 2020-11-30 2024-03-25 Инново Терапьютикс Инк. Фармацевтическая композиция для предупрежденияили лечения раны или рубца, включающая бензбромарон

Also Published As

Publication number Publication date
SK148199A3 (en) 2001-09-11
HRP980244A2 (en) 1999-02-28
JP2000513020A (ja) 2000-10-03
YU55899A (sh) 2003-08-29
HUP0001286A3 (en) 2000-12-28
KR20040004406A (ko) 2004-01-13
AR039628A2 (es) 2005-03-02
BR9808720A (pt) 2000-07-11
PE72599A1 (es) 1999-08-12
NZ500183A (en) 2002-04-26
UY24989A1 (es) 2001-10-25
TNSN98059A1 (fr) 2005-03-15
CA2288759A1 (fr) 1998-11-12
KR20010012300A (ko) 2001-02-15
EP0988034A1 (fr) 2000-03-29
AR011726A1 (es) 2000-08-30
HUP0001286A2 (hu) 2000-11-28
IL132570A0 (en) 2001-03-19
ZA983722B (en) 1999-11-04
EA199900895A1 (ru) 2000-06-26
GT199800063A (es) 1999-10-26
WO1998050033A1 (fr) 1998-11-12
AU6932198A (en) 1998-11-27
OA11213A (en) 2003-07-14
PA8450601A1 (es) 2000-05-24
PL337003A1 (en) 2000-07-31
DZ2479A1 (fr) 2003-02-01
AP9801234A0 (en) 1999-11-04
TW590773B (en) 2004-06-11
NO995389D0 (no) 1999-11-04
MA26491A1 (fr) 2004-12-20
ID21311A (id) 1999-05-20
IS5220A (is) 1999-10-19
BG103852A (en) 2000-06-30
CN1255059A (zh) 2000-05-31
NO995389L (no) 2000-01-04

Similar Documents

Publication Publication Date Title
EA003696B1 (ru) Селективный в отношении цог-2 карпрофен для лечения боли и воспаления у собак
US6399647B2 (en) Amide derivatives for antiangiogenic and/or antitumorigenic use
McLean et al. Toxicology of frequently encountered nonsteroidal anti-inflammatory drugs in dogs and cats: an update
DK2049482T3 (en) Positively charged, water-soluble prodrugs of aryl and heteroaryl acetic acids with very fast skin penetration rate
US5968974A (en) Method of treating colonic adenomas
NL8005357A (nl) In water oplosbare derivaten van niet-steriode ont- stekingsremmende middelen en een werkwijze voor de vervaardiging daarvan.
KR20180124976A (ko) 신경교종을 포함하는 암을 치료하기 위해 에플로르니틴 및 이의 유도체 및 동족체를 사용하기 위한 조성물 및 방법
AU706089B2 (en) Method of treating colonic adenomas
US6689382B2 (en) Soft shell gelatin capsules containing non-steroidal anti-inflammatories
US20030212123A1 (en) COX-2 selective carprofen for treating pain and inflammation in dogs
CN101711279A (zh) Tp调节剂在阿司匹林敏感群体以及其他群体中治疗心血管疾病的用途
Zhao et al. Clinically approved small-molecule drugs for the treatment of rheumatoid arthritis
US20020045605A1 (en) Method of treating colonic adenomas
AU773615B2 (en) COX-2 selective carprofen for treating pain and inflammation in dogs
WO2003094924A1 (fr) Therapie de combinaison destinee a traiter des maladies a mediation par cyclooxygenase-2 chez des malades presentant un risque d'accident cardiovasculaire thrombotique
JP2010508304A (ja) ホスホリパーゼ酵素阻害剤の半固体製剤
CZ9903896A3 (cs) Léčivo, farmaceutický přípravek a souprava pro léčení nebo prevenci bolesti a zánětlivých procesů
JP2004511436A (ja) 失禁用医薬
NZ516914A (en) Compositions containing COX-2 selective carprofen and derivatives thereof for treating pain and inflammation in dogs
ZA200410123B (en) Annelated pyrrole compounds as proton pump inhibitors for treating ulcer
AU717966B2 (en) Method of treating colonic adenomas
US20050215611A1 (en) Combination therapy for treating cyclooxygenase-2 mediated diseases in patients at risk of thrombotic cardiovascular events
MXPA99008048A (en) Oxynolic developers oxidonitric releases for analgesic, anti-inflammatory use and as a sick modifier

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU