DZ2438A1 - Atropisomères de 3-hétéroaryl-4(3h)-quinazolinones. - Google Patents

Atropisomères de 3-hétéroaryl-4(3h)-quinazolinones.

Info

Publication number
DZ2438A1
DZ2438A1 DZ980048A DZ980048A DZ2438A1 DZ 2438 A1 DZ2438 A1 DZ 2438A1 DZ 980048 A DZ980048 A DZ 980048A DZ 980048 A DZ980048 A DZ 980048A DZ 2438 A1 DZ2438 A1 DZ 2438A1
Authority
DZ
Algeria
Prior art keywords
quinazolinones
atropisomers
heteroaryl
Prior art date
Application number
DZ980048A
Other languages
English (en)
Inventor
Bertrand Leo Chenard
Keith Michael De Vries
Winard Mckowan Welch Jr
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of DZ2438A1 publication Critical patent/DZ2438A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DZ980048A 1997-02-28 1998-02-25 Atropisomères de 3-hétéroaryl-4(3h)-quinazolinones. DZ2438A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3854097P 1997-02-28 1997-02-28

Publications (1)

Publication Number Publication Date
DZ2438A1 true DZ2438A1 (fr) 2003-01-11

Family

ID=21900535

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ980048A DZ2438A1 (fr) 1997-02-28 1998-02-25 Atropisomères de 3-hétéroaryl-4(3h)-quinazolinones.

Country Status (40)

Country Link
US (1) US6380204B1 (fr)
EP (1) EP0964860B1 (fr)
JP (1) JP3299990B2 (fr)
KR (1) KR20000075812A (fr)
CN (1) CN1248254A (fr)
AP (1) AP9801202A0 (fr)
AR (1) AR011886A1 (fr)
AT (1) ATE264854T1 (fr)
AU (1) AU732448B2 (fr)
BG (1) BG103687A (fr)
BR (1) BR9807807A (fr)
CA (1) CA2282279C (fr)
CO (1) CO4950615A1 (fr)
DE (1) DE69823339T2 (fr)
DK (1) DK0964860T3 (fr)
DZ (1) DZ2438A1 (fr)
EA (1) EA001961B1 (fr)
ES (1) ES2218801T3 (fr)
GT (1) GT199800039A (fr)
HN (1) HN1998000028A (fr)
HR (1) HRP980108B1 (fr)
HU (1) HUP0000935A3 (fr)
ID (1) ID23435A (fr)
IL (1) IL130897A0 (fr)
IS (1) IS5141A (fr)
MA (1) MA24485A1 (fr)
NO (1) NO994178D0 (fr)
NZ (1) NZ336627A (fr)
OA (1) OA11088A (fr)
PA (1) PA8446901A1 (fr)
PE (1) PE57999A1 (fr)
PL (1) PL335307A1 (fr)
PT (1) PT964860E (fr)
SK (1) SK113199A3 (fr)
TN (1) TNSN98034A1 (fr)
TR (1) TR199902094T2 (fr)
TW (1) TW530055B (fr)
UA (1) UA58536C2 (fr)
WO (1) WO1998038187A1 (fr)
ZA (1) ZA981665B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323208B1 (en) 1997-09-05 2001-11-27 Pfizer Inc Atropisomers of 2,3-disubstituted-(5.6)-heteroaryl fused-pyrimidin-4-ones
JPH11279158A (ja) * 1998-02-09 1999-10-12 Pfizer Prod Inc キナゾリン―4―オン誘導体の製造方法
US6890930B1 (en) * 1999-09-28 2005-05-10 3-Dimensional Pharmaceuticals, Inc. Quinazolinones
BRPI0413372A (pt) * 2003-08-08 2006-10-17 Ulysses Pharmaceutical Product composto e composições de nitrofuranos de quinazolinil halogenados, seus métodos de preparação e usos como agentes antibacterianos
US20080146562A1 (en) * 2003-08-08 2008-06-19 Ulysses Pharmaceutical Products Inc., Halogenated quinazolinyl nitrofurans as antibacterial agents
GB0416730D0 (en) 2004-07-27 2004-09-01 Novartis Ag Organic compounds
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
AU2006311883A1 (en) 2005-11-04 2007-05-18 Hydra Biosciences, Inc. Compounds for modulating TRPV3 function
CN101547922B (zh) * 2006-10-04 2012-06-20 辉瑞产品公司 作为钙受体拮抗剂的吡啶并[4,3-d]嘧啶-4(3H)-酮衍生物
WO2008140750A1 (fr) * 2007-05-10 2008-11-20 Hydra Biosciences Inc. Composés modulant la fonction du trp v3
BRPI1012333A2 (pt) * 2009-03-24 2016-03-29 Gilead Calistoga Llc atropisômeros de derivados de 2-purinil-3-tolil-quinazolinonas e métodos de uso
WO2010138577A1 (fr) * 2009-05-29 2010-12-02 Merck Sharp & Dohme Corp. Inhibiteurs de pde10 radio-marqués
WO2013105985A1 (fr) * 2011-02-28 2013-07-18 Philadelphia Health & Education Corporation Inhibiteurs à petites molécules de la recombinase rad51 et procédés associés
JP2023512664A (ja) 2020-01-29 2023-03-28 カマリ ファーマ リミテッド 皮膚障害の治療に使用するための化合物及び組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1298603A (en) 1970-04-06 1972-12-06 Karamchand Premchand Private Quinazolinone derivatives
US4183931A (en) 1977-09-08 1980-01-15 Research Corporation 2-Ketoalkyl-4(3H)-quinazolinones
WO1992013535A1 (fr) * 1991-02-06 1992-08-20 Research Corporation Technologies, Inc. Quinazolones substituees a activite anticonvulsivante
SK284108B6 (sk) 1996-05-15 2004-09-08 Pfizer Inc. 2,3-Disubstituované 4(3H)-chinazolinóny, ich použitie a farmaceutické kompozície s ich obsahom
EP0807633B1 (fr) 1996-05-15 2002-11-06 Pfizer Inc. (5,6)-Pyrimidin-4-ones condensées à hétéroaryle, substituées en 2,3

Also Published As

Publication number Publication date
AP9801202A0 (en) 1999-08-26
AU5775998A (en) 1998-09-18
US6380204B1 (en) 2002-04-30
ATE264854T1 (de) 2004-05-15
IS5141A (is) 1999-07-30
PE57999A1 (es) 1999-06-21
HRP980108A2 (en) 1998-12-31
ES2218801T3 (es) 2004-11-16
NO994178L (no) 1999-08-27
NZ336627A (en) 2000-12-22
OA11088A (en) 2002-03-15
PT964860E (pt) 2004-07-30
DK0964860T3 (da) 2004-07-26
TW530055B (en) 2003-05-01
TR199902094T2 (xx) 1999-12-21
JP2000509732A (ja) 2000-08-02
PL335307A1 (en) 2000-04-10
IL130897A0 (en) 2001-01-28
JP3299990B2 (ja) 2002-07-08
PA8446901A1 (es) 2000-05-24
CA2282279C (fr) 2004-11-02
BR9807807A (pt) 2000-02-22
TNSN98034A1 (fr) 2005-03-15
MA24485A1 (fr) 1998-10-01
EP0964860A1 (fr) 1999-12-22
UA58536C2 (uk) 2003-08-15
ZA981665B (en) 1999-08-17
AU732448B2 (en) 2001-04-26
DE69823339D1 (de) 2004-05-27
HRP980108B1 (en) 2004-10-31
EA001961B1 (ru) 2001-10-22
CN1248254A (zh) 2000-03-22
CA2282279A1 (fr) 1998-09-03
GT199800039A (es) 1999-08-13
CO4950615A1 (es) 2000-09-01
KR20000075812A (ko) 2000-12-26
WO1998038187A1 (fr) 1998-09-03
AR011886A1 (es) 2000-09-13
BG103687A (en) 2000-06-30
SK113199A3 (en) 2001-10-08
EA199900689A1 (ru) 2000-02-28
ID23435A (id) 2000-04-20
NO994178D0 (no) 1999-08-27
DE69823339T2 (de) 2005-05-12
HN1998000028A (es) 1999-02-09
EP0964860B1 (fr) 2004-04-21
HUP0000935A2 (hu) 2001-04-28
HUP0000935A3 (en) 2002-04-29

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