MA24485A1 - Atropisomeres de 3-heteroaryl-4(3h)-quinazo linones . - Google Patents

Atropisomeres de 3-heteroaryl-4(3h)-quinazo linones .

Info

Publication number
MA24485A1
MA24485A1 MA24979A MA24979A MA24485A1 MA 24485 A1 MA24485 A1 MA 24485A1 MA 24979 A MA24979 A MA 24979A MA 24979 A MA24979 A MA 24979A MA 24485 A1 MA24485 A1 MA 24485A1
Authority
MA
Morocco
Prior art keywords
linones
quinazo
atropisomers
heteroaryl
quinazo linones
Prior art date
Application number
MA24979A
Other languages
English (en)
Inventor
Mc Kowan Welch Willard Jr
Michael Devries Keith
Leo Chennard Bertrand
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MA24485A1 publication Critical patent/MA24485A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MA24979A 1997-02-28 1998-02-25 Atropisomeres de 3-heteroaryl-4(3h)-quinazo linones . MA24485A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3854097P 1997-02-28 1997-02-28

Publications (1)

Publication Number Publication Date
MA24485A1 true MA24485A1 (fr) 1998-10-01

Family

ID=21900535

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24979A MA24485A1 (fr) 1997-02-28 1998-02-25 Atropisomeres de 3-heteroaryl-4(3h)-quinazo linones .

Country Status (40)

Country Link
US (1) US6380204B1 (fr)
EP (1) EP0964860B1 (fr)
JP (1) JP3299990B2 (fr)
KR (1) KR20000075812A (fr)
CN (1) CN1248254A (fr)
AP (1) AP9801202A0 (fr)
AR (1) AR011886A1 (fr)
AT (1) ATE264854T1 (fr)
AU (1) AU732448B2 (fr)
BG (1) BG103687A (fr)
BR (1) BR9807807A (fr)
CA (1) CA2282279C (fr)
CO (1) CO4950615A1 (fr)
DE (1) DE69823339T2 (fr)
DK (1) DK0964860T3 (fr)
DZ (1) DZ2438A1 (fr)
EA (1) EA001961B1 (fr)
ES (1) ES2218801T3 (fr)
GT (1) GT199800039A (fr)
HN (1) HN1998000028A (fr)
HR (1) HRP980108B1 (fr)
HU (1) HUP0000935A3 (fr)
ID (1) ID23435A (fr)
IL (1) IL130897A0 (fr)
IS (1) IS5141A (fr)
MA (1) MA24485A1 (fr)
NO (1) NO994178L (fr)
NZ (1) NZ336627A (fr)
OA (1) OA11088A (fr)
PA (1) PA8446901A1 (fr)
PE (1) PE57999A1 (fr)
PL (1) PL335307A1 (fr)
PT (1) PT964860E (fr)
SK (1) SK113199A3 (fr)
TN (1) TNSN98034A1 (fr)
TR (1) TR199902094T2 (fr)
TW (1) TW530055B (fr)
UA (1) UA58536C2 (fr)
WO (1) WO1998038187A1 (fr)
ZA (1) ZA981665B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323208B1 (en) * 1997-09-05 2001-11-27 Pfizer Inc Atropisomers of 2,3-disubstituted-(5.6)-heteroaryl fused-pyrimidin-4-ones
JPH11279158A (ja) * 1998-02-09 1999-10-12 Pfizer Prod Inc キナゾリン―4―オン誘導体の製造方法
US6890930B1 (en) * 1999-09-28 2005-05-10 3-Dimensional Pharmaceuticals, Inc. Quinazolinones
CA2534405A1 (fr) * 2003-08-08 2005-02-17 Ulysses Pharmaceutical Products Inc. Quinazolinyl nitrofuranes halogenes utilises comme agents antibacteriens
US20080146562A1 (en) * 2003-08-08 2008-06-19 Ulysses Pharmaceutical Products Inc., Halogenated quinazolinyl nitrofurans as antibacterial agents
GB0416730D0 (en) 2004-07-27 2004-09-01 Novartis Ag Organic compounds
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
TWI409070B (zh) * 2005-11-04 2013-09-21 Hydra Biosciences Inc 用於調節trpv3功能之化合物
MX2009003673A (es) * 2006-10-04 2009-04-22 Pfizer Prod Inc Derivados de piridido[4,3-d]pirimidin-4(3h)-ona como antagonistas de los receptores de calcio.
WO2008140750A1 (fr) * 2007-05-10 2008-11-20 Hydra Biosciences Inc. Composés modulant la fonction du trp v3
WO2010111432A1 (fr) * 2009-03-24 2010-09-30 Calistoga Pharmaceuticals Inc. Atropisomères de dérivés de 2-purinyl-3-tolyl-quinazolinone et procédés d'utilisation
JP5718323B2 (ja) * 2009-05-29 2015-05-13 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. 放射標識されたpde10阻害剤
US9216177B2 (en) 2011-02-28 2015-12-22 Drexel University Small molecular inhibitors of RAD51 recombinase and methods thereof
AU2021212754A1 (en) 2020-01-29 2022-08-04 Kamari Pharma Ltd. Compounds and compositions for use in treating skin disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1298603A (en) * 1970-04-06 1972-12-06 Karamchand Premchand Private Quinazolinone derivatives
US4183931A (en) * 1977-09-08 1980-01-15 Research Corporation 2-Ketoalkyl-4(3H)-quinazolinones
WO1992013535A1 (fr) 1991-02-06 1992-08-20 Research Corporation Technologies, Inc. Quinazolones substituees a activite anticonvulsivante
ES2184960T3 (es) 1996-05-15 2003-04-16 Pfizer Nuevas pirimidin-4-onas-(5,6)-heteroaril condensadas 2,3 disustituidas.
KR100375155B1 (ko) 1996-05-15 2003-08-19 화이자 인코포레이티드 신규한2,3-이치환된-4(3에이치)-퀴나졸리논

Also Published As

Publication number Publication date
HRP980108B1 (en) 2004-10-31
HN1998000028A (es) 1999-02-09
EA199900689A1 (ru) 2000-02-28
SK113199A3 (en) 2001-10-08
JP2000509732A (ja) 2000-08-02
AP9801202A0 (en) 1999-08-26
AR011886A1 (es) 2000-09-13
AU732448B2 (en) 2001-04-26
PT964860E (pt) 2004-07-30
UA58536C2 (uk) 2003-08-15
EA001961B1 (ru) 2001-10-22
HUP0000935A2 (hu) 2001-04-28
HUP0000935A3 (en) 2002-04-29
NO994178D0 (no) 1999-08-27
IL130897A0 (en) 2001-01-28
DE69823339D1 (de) 2004-05-27
HRP980108A2 (en) 1998-12-31
IS5141A (is) 1999-07-30
ID23435A (id) 2000-04-20
DE69823339T2 (de) 2005-05-12
CA2282279A1 (fr) 1998-09-03
EP0964860A1 (fr) 1999-12-22
US6380204B1 (en) 2002-04-30
BG103687A (en) 2000-06-30
AU5775998A (en) 1998-09-18
PE57999A1 (es) 1999-06-21
ES2218801T3 (es) 2004-11-16
DZ2438A1 (fr) 2003-01-11
ZA981665B (en) 1999-08-17
PA8446901A1 (es) 2000-05-24
BR9807807A (pt) 2000-02-22
EP0964860B1 (fr) 2004-04-21
CA2282279C (fr) 2004-11-02
CO4950615A1 (es) 2000-09-01
OA11088A (en) 2002-03-15
WO1998038187A1 (fr) 1998-09-03
PL335307A1 (en) 2000-04-10
GT199800039A (es) 1999-08-13
DK0964860T3 (da) 2004-07-26
CN1248254A (zh) 2000-03-22
ATE264854T1 (de) 2004-05-15
KR20000075812A (ko) 2000-12-26
TR199902094T2 (xx) 1999-12-21
NZ336627A (en) 2000-12-22
JP3299990B2 (ja) 2002-07-08
NO994178L (no) 1999-08-27
TW530055B (en) 2003-05-01
TNSN98034A1 (fr) 2005-03-15

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