DK8787A - Indolderivater og fremgangsmaade til fremstilling deraf - Google Patents

Indolderivater og fremgangsmaade til fremstilling deraf

Info

Publication number
DK8787A
DK8787A DK008787A DK8787A DK8787A DK 8787 A DK8787 A DK 8787A DK 008787 A DK008787 A DK 008787A DK 8787 A DK8787 A DK 8787A DK 8787 A DK8787 A DK 8787A
Authority
DK
Denmark
Prior art keywords
procedures
preparing
index derivatives
derivatives
index
Prior art date
Application number
DK008787A
Other languages
Danish (da)
English (en)
Other versions
DK8787D0 (da
Inventor
Keith Mills
Colin David Eldred
Alexander William Oxford
Ian Harold Coates
David Edmund Bays
Colin Frederick Webb
Michael Dennis Dowle
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DK8787D0 publication Critical patent/DK8787D0/da
Publication of DK8787A publication Critical patent/DK8787A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK008787A 1986-01-08 1987-01-08 Indolderivater og fremgangsmaade til fremstilling deraf DK8787A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868600397A GB8600397D0 (en) 1986-01-08 1986-01-08 Chemical compounds

Publications (2)

Publication Number Publication Date
DK8787D0 DK8787D0 (da) 1987-01-08
DK8787A true DK8787A (da) 1987-07-09

Family

ID=10591074

Family Applications (1)

Application Number Title Priority Date Filing Date
DK008787A DK8787A (da) 1986-01-08 1987-01-08 Indolderivater og fremgangsmaade til fremstilling deraf

Country Status (23)

Country Link
US (1) US4855314A (enExample)
EP (1) EP0240096A1 (enExample)
JP (1) JPS62228056A (enExample)
KR (1) KR870007116A (enExample)
CN (1) CN1030409A (enExample)
AU (1) AU597325B2 (enExample)
BE (1) BE1000071A4 (enExample)
CH (1) CH672637A5 (enExample)
DE (1) DE3700408A1 (enExample)
DK (1) DK8787A (enExample)
FI (1) FI870062A7 (enExample)
FR (1) FR2595351B1 (enExample)
GB (2) GB8600397D0 (enExample)
HU (1) HU198685B (enExample)
IL (1) IL81201A (enExample)
IT (1) IT1205849B (enExample)
LU (1) LU86732A1 (enExample)
NL (1) NL8700026A (enExample)
NO (1) NO870075L (enExample)
NZ (1) NZ218868A (enExample)
PH (1) PH24741A (enExample)
PT (1) PT84075B (enExample)
ZA (1) ZA87105B (enExample)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8724912D0 (en) 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
GB8823731D0 (en) * 1988-10-10 1988-11-16 Smith Kline French Lab Biologically active compounds
MC2210A1 (fr) * 1990-06-07 1992-11-26 Wellcome Found Composes heterocycliques therapeutiques,leur utilisation et procede pour les preparer
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
ES2104733T3 (es) * 1990-10-15 1997-10-16 Pfizer Derivados de indol.
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
CA2061520C (en) * 1991-03-27 2003-04-22 Lawrence J. Daher Delivery system for enhanced onset and increased potency
ATE190608T1 (de) * 1991-11-25 2000-04-15 Pfizer 5-(hetero- oder carbocyclylamino)-indol derivate, deren herstellung und deren verwendung als 5-ht1 agonisten
TW288010B (enExample) * 1992-03-05 1996-10-11 Pfizer
UA27467C2 (uk) * 1992-04-07 2000-09-15 Пфайзер Інк. ПОХІДНІ ІНДОЛУ ЯК 5-НТ<sub>1</sub> АГОНІСТИ ТА ПРОМІЖНІ СПОЛУКИ
US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
GB9207930D0 (en) * 1992-04-10 1992-05-27 Pfizer Ltd Indoles
CZ282653B6 (cs) * 1992-04-10 1997-08-13 Pfizer Inc. Acylaminoindolové deriváty představující 5-HT1 agonisty, způsob jejich přípravy, farmaceutické prostředky obsahující tyto látky, jejich použití a meziprodukty postupu přípravy
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
TW251284B (enExample) * 1992-11-02 1995-07-11 Pfizer
FR2707639B1 (fr) * 1993-06-30 1995-10-13 Pf Medicament Nouveaux composés indoliques dérivés d'arylamines comme ligands sélectifs des récepteurs 5HT1D et 5HT1B.
ES2070772B1 (es) * 1993-08-09 1996-02-16 Pfizer Derivados de acilaminoindol
DK0716649T3 (da) * 1993-08-31 1999-02-08 Pfizer 5-Arylindolderivater
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
GB9417310D0 (en) 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
FR2749846B1 (fr) * 1996-06-17 1998-09-11 Pf Medicament Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
ES2266227T3 (es) * 2000-08-21 2007-03-01 Pacific Corporation Nuevos compuestos de (tio)urea y composiciones farmaceuticas que los contienen.
US7297711B2 (en) * 2002-06-21 2007-11-20 Suven Life Sciences Limited Arylalkyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
EP1523486B1 (en) * 2002-06-21 2007-11-07 Suven Life Sciences Limited Tetracyclic arylsulfonyl indoles having serotonin receptor affinity
DE60309324T2 (de) 2002-06-21 2007-05-10 Suven Life Sciences Ltd. Tetracyclische arylcarbonyl indole mit serotoninrezeptoraffinität als arzneimittel, verfahren zu ihrer herstellung und pharmazeutische zubereitungen
BRPI0315958B8 (pt) 2002-11-28 2021-05-25 Suven Life Sciences Ltd composto, composição farmacêutica, processo para a preparação de um composto, novos intermediários e uso do composto
NZ540840A (en) * 2002-11-28 2008-12-24 Suven Life Sciences Ltd N-arylsulfonyl-3-substituted indoles having serotonin receptor affinity, process for their preparation and pharmaceutical composition containing them
SI1581538T1 (sl) * 2002-12-18 2007-08-31 Suven Life Sciences Ltd Tetraciklični 3-substituirani indoli z afiniteto za receptor serotonina
JP4897221B2 (ja) 2002-12-20 2012-03-14 チバ ホールディング インコーポレーテッド アミン類の合成及びその合成のための中間体
EP2032532B8 (en) * 2006-06-12 2015-07-01 Novartis AG Process for making salts of N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472870A (en) * 1966-08-29 1969-10-14 Mead Johnson & Co Sulfonamidotryptamines
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
GB2083463B (en) * 1980-08-12 1984-05-10 Glaxo Group Ltd Heterocyclic compounds
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
GB8332437D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8332435D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8332434D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Production of chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
PT84075B (pt) 1989-07-31
BE1000071A4 (fr) 1988-02-02
DK8787D0 (da) 1987-01-08
NL8700026A (nl) 1987-08-03
ZA87105B (en) 1987-09-30
AU6742087A (en) 1987-07-09
PH24741A (en) 1990-10-01
GB8700382D0 (en) 1987-02-11
HUT46891A (en) 1988-12-28
GB2185020B (en) 1990-05-16
AU597325B2 (en) 1990-05-31
FI870062A7 (fi) 1987-07-09
FR2595351B1 (fr) 1990-07-13
FI870062A0 (fi) 1987-01-08
IL81201A (en) 1991-06-10
PT84075A (en) 1987-02-01
NZ218868A (en) 1990-04-26
JPS62228056A (ja) 1987-10-06
DE3700408A1 (de) 1987-07-09
KR870007116A (ko) 1987-08-14
HU198685B (en) 1989-11-28
IT8747507A0 (it) 1987-01-08
FR2595351A1 (fr) 1987-09-11
IL81201A0 (en) 1987-08-31
CN1030409A (zh) 1989-01-18
LU86732A1 (fr) 1988-02-02
EP0240096A1 (en) 1987-10-07
GB8600397D0 (en) 1986-02-12
IT1205849B (it) 1989-03-31
CH672637A5 (enExample) 1989-12-15
NO870075L (no) 1987-07-09
NO870075D0 (no) 1987-01-08
US4855314A (en) 1989-08-08
GB2185020A (en) 1987-07-08

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