DK527789D0 - Dithiocarbamoylquinoloner og sammensaetninger omfattende samme - Google Patents
Dithiocarbamoylquinoloner og sammensaetninger omfattende sammeInfo
- Publication number
- DK527789D0 DK527789D0 DK527789A DK527789A DK527789D0 DK 527789 D0 DK527789 D0 DK 527789D0 DK 527789 A DK527789 A DK 527789A DK 527789 A DK527789 A DK 527789A DK 527789 D0 DK527789 D0 DK 527789D0
- Authority
- DK
- Denmark
- Prior art keywords
- dithiocarbamoylquinolons
- comprehensive same
- compositions
- compositions comprehensive
- same
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26194888A | 1988-10-24 | 1988-10-24 | |
US41802989A | 1989-10-12 | 1989-10-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK527789D0 true DK527789D0 (da) | 1989-10-24 |
DK527789A DK527789A (da) | 1990-04-25 |
Family
ID=26948929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK527789A DK527789A (da) | 1988-10-24 | 1989-10-24 | Dithiocarbamoylquinoloner og sammensaetninger omfattende samme |
Country Status (10)
Country | Link |
---|---|
US (2) | US5387748A (da) |
EP (1) | EP0366643A3 (da) |
JP (1) | JP2875015B2 (da) |
KR (1) | KR900006333A (da) |
AU (1) | AU631379B2 (da) |
CA (1) | CA2001203C (da) |
DK (1) | DK527789A (da) |
NZ (1) | NZ231111A (da) |
PH (1) | PH29981A (da) |
WO (1) | WO1990004591A1 (da) |
Families Citing this family (36)
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US5147871A (en) * | 1986-07-03 | 1992-09-15 | Hoffmann La-Roche, Inc. | Anti-bacterial cephalosporin compounds |
US5336768A (en) * | 1988-05-24 | 1994-08-09 | Hoffmann-La Roche Inc. | Antibacterial cephalosporin compounds |
CS273349B2 (en) * | 1988-03-31 | 1991-03-12 | Hoffmann La Roche | Method of cephalosporin's new derivatives production |
CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
EP0997466A1 (en) * | 1988-10-24 | 2000-05-03 | PROCTER & GAMBLE PHARMACEUTICALS, INC. | Novel antimicrobial lactam-quinolones |
US5273973A (en) * | 1988-10-24 | 1993-12-28 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl esters |
US5180719A (en) * | 1988-10-24 | 1993-01-19 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl lactam esters |
DE68928925T2 (de) * | 1988-10-24 | 1999-08-26 | Procter & Gamble Pharmaceuticals | Antimikrobielle Fluorochinolonylcephemderivate |
US5491139A (en) * | 1988-10-24 | 1996-02-13 | The Procter & Gamble Company | Antimicrobial quinolonyl lactams |
US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
US5162523A (en) * | 1989-07-21 | 1992-11-10 | Hoffmann-La Roche Inc. | Cephalosporin antibacterial compounds |
US5159077A (en) * | 1989-07-21 | 1992-10-27 | Hoffmann-La Roche Inc. | Penam antibacterial compounds |
CA2078444A1 (en) * | 1990-04-18 | 1991-10-19 | Thomas P. Demuth, Jr. | Antimicrobial quinolonyl lactams |
KR950005301B1 (ko) * | 1990-09-04 | 1995-05-23 | 주식회사대웅제약 | 신규한 퀴놀론 카르복실산 유도체 |
AU4272793A (en) * | 1993-04-24 | 1994-11-21 | Korea Research Institute Of Chemical Technology | Novel quinolone carboxylic acid derivatives and process for preparing the same |
JP3328936B2 (ja) * | 1993-09-03 | 2002-09-30 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 5ht1dレセプター拮抗薬用インドールおよびインドリン誘導体 |
KR950018003A (ko) * | 1993-12-09 | 1995-07-22 | 스미스클라인 비참 피엘씨 | 신규한 퀴놀론 유도체 및 그의 제조 방법 |
EP0927159A1 (en) * | 1996-09-10 | 1999-07-07 | Medinox, Inc. | Polydithiocarbamate-containing macromolecules and the use thereof for therapeutic and diagnostic applications |
DE19652239A1 (de) * | 1996-12-16 | 1998-06-18 | Bayer Ag | Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen |
PL339408A1 (en) | 1997-09-15 | 2000-12-18 | Procter & Gamble | Antimicrobial quinolones, agents containing them and their applications |
WO2003027113A1 (en) | 2001-09-26 | 2003-04-03 | Bayer Pharmaceuticals Corporation | 1,6-naphthyridine derivatives as antidiabetics |
AU2004267052B2 (en) * | 2003-08-12 | 2009-02-05 | Achillion Pharmaceuticals, Inc. | Isothiazoloquinolones and related compounds as anti-infective agents |
JP2008509909A (ja) * | 2004-08-11 | 2008-04-03 | ウィリアムスバーグ・ホールディングス・エルエルシー | 心毒性のない医薬化合物 |
CN101039668A (zh) * | 2004-08-13 | 2007-09-19 | 先灵-普劳有限公司 | 包含抗菌素、三唑和皮质类固醇的药物制剂 |
WO2006118605A2 (en) * | 2004-11-11 | 2006-11-09 | Achillion Pharmaceuticals, Inc. | 8a, 9-dihydro-4a-h-isothiazolo[5,4-b] quinoline-3, 4-diones and related compounds as anti-infective agents |
WO2006074317A1 (en) * | 2005-01-05 | 2006-07-13 | Achillion Pharmaceuticals, Inc. | 1-thia-2,4a-diaza-cyclopenta[b]naphthalene-3,4-diones and related compounds as anti-infective agents |
US7199128B2 (en) * | 2005-02-02 | 2007-04-03 | Achillion Pharmaceuticals, Inc. | 8-N-substituted-2H-isothiazolo[5,4-b]quinolizine-3,4-diones and related compounds as antiinfective agents |
MX2007009895A (es) * | 2005-02-16 | 2007-10-03 | Achillion Pharmaceuticals Inc | Nuevas isotiazoloquinolonas y compuestos relacionados como agentes anti-infecciosos. |
PT1913004E (pt) | 2005-07-27 | 2010-12-09 | Achillion Pharmaceuticals Inc | 8-metoxi-9h-isotiazolo[5,4-b]quinolina-3,4-dionas e compostos relacionados como agentes anti-infecciosos |
DK2383271T3 (da) * | 2006-03-13 | 2013-10-07 | Kyorin Seiyaku Kk | Aminoquinoloner som GSK-3-inhibitorer |
JP2009531418A (ja) * | 2006-03-28 | 2009-09-03 | ザ プロクター アンド ギャンブル カンパニー | キノロン中間体調製のためのカップリング方法 |
MY148393A (en) * | 2006-03-28 | 2013-04-15 | Taigen Biotechnology Co Ltd | Malate salts, and polymorphs of (3s, 5s)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid |
WO2009035634A2 (en) * | 2007-09-11 | 2009-03-19 | Activx Biosciences, Inc. | Cyanoaminoquinolones and tetrazoloaminoquinolones as gsk-3 inhibitors |
BRPI0816814B1 (pt) | 2007-09-12 | 2021-08-31 | Kyorin Pharmaceutical Co. Ltd | Composto, composição farmacêutica e uso de um composto |
WO2010104205A1 (en) * | 2009-03-11 | 2010-09-16 | Kyorin Pharmaceutical Co., Ltd. | 7-cycloalkylaminoquinolones as gsk-3 inhibitors |
EA201101451A1 (ru) * | 2009-04-03 | 2012-03-30 | Ачиллион Фармасьютикалз, Инк. | Гидрокситиенохинолоны и родственные соединения как противоинфекционные средства |
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NZ227470A (en) * | 1987-12-28 | 1991-06-25 | Hoffmann La Roche | Acyl derivatives of substituted cephem compounds; pharmaceutical compositions and methods for preparation and treatment |
US5336768A (en) * | 1988-05-24 | 1994-08-09 | Hoffmann-La Roche Inc. | Antibacterial cephalosporin compounds |
YU63689A (en) * | 1988-03-31 | 1991-06-30 | Hoffmann La Roche | Acyl derivatives |
JPH01258684A (ja) * | 1988-04-07 | 1989-10-16 | Banyu Pharmaceut Co Ltd | 3‐置換キノリニウムチオメチルセファロスポリン誘導体 |
ATE113953T1 (de) * | 1988-05-10 | 1994-11-15 | Ici Plc | Cephalosporine, verfahren zu ihrer herstellung und pharmazeutische präparate. |
EP0997466A1 (en) * | 1988-10-24 | 2000-05-03 | PROCTER & GAMBLE PHARMACEUTICALS, INC. | Novel antimicrobial lactam-quinolones |
CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
ES2148135T3 (es) * | 1988-10-24 | 2000-10-16 | Norwich Eaton Pharma | Nuevos esteres antimicrobianos de quinolonil lactamas. |
EP0366193A3 (en) * | 1988-10-24 | 1992-01-08 | Norwich Eaton Pharmaceuticals, Inc. | Novel antimicrobial quinolonyl lactams |
DE68928925T2 (de) * | 1988-10-24 | 1999-08-26 | Procter & Gamble Pharmaceuticals | Antimikrobielle Fluorochinolonylcephemderivate |
US5273973A (en) * | 1988-10-24 | 1993-12-28 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl esters |
US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
ZA912279B (en) * | 1990-04-09 | 1992-02-26 | Hoffmann La Roche | Carbapenem compounds |
CA2078444A1 (en) * | 1990-04-18 | 1991-10-19 | Thomas P. Demuth, Jr. | Antimicrobial quinolonyl lactams |
US5066800A (en) * | 1990-04-27 | 1991-11-19 | Hoffmann-La Roche Inc. | Qunoline intermediates useful therein for synthesizing antibacterial compounds |
US5112967A (en) * | 1990-04-27 | 1992-05-12 | Hoffmann-La Roches Inc. | Process for synthesizing antibacterial cephalosporin compounds |
-
1989
- 1989-10-23 CA CA002001203A patent/CA2001203C/en not_active Expired - Fee Related
- 1989-10-24 EP EP19890870161 patent/EP0366643A3/en not_active Ceased
- 1989-10-24 JP JP2500634A patent/JP2875015B2/ja not_active Expired - Lifetime
- 1989-10-24 PH PH39399A patent/PH29981A/en unknown
- 1989-10-24 DK DK527789A patent/DK527789A/da not_active Application Discontinuation
- 1989-10-24 WO PCT/US1989/004806 patent/WO1990004591A1/en unknown
- 1989-10-24 KR KR1019890015237A patent/KR900006333A/ko not_active Application Discontinuation
- 1989-10-24 NZ NZ231111A patent/NZ231111A/en unknown
- 1989-10-24 AU AU43685/89A patent/AU631379B2/en not_active Ceased
-
1991
- 1991-05-02 US US07/696,985 patent/US5387748A/en not_active Expired - Fee Related
-
1994
- 1994-10-21 US US08/327,063 patent/US5672600A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5672600A (en) | 1997-09-30 |
JP2875015B2 (ja) | 1999-03-24 |
WO1990004591A1 (en) | 1990-05-03 |
AU631379B2 (en) | 1992-11-26 |
EP0366643A2 (en) | 1990-05-02 |
AU4368589A (en) | 1990-04-26 |
DK527789A (da) | 1990-04-25 |
JPH03503533A (ja) | 1991-08-08 |
CA2001203C (en) | 2001-02-13 |
EP0366643A3 (en) | 1991-12-04 |
PH29981A (en) | 1996-10-29 |
US5387748A (en) | 1995-02-07 |
CA2001203A1 (en) | 1990-04-24 |
NZ231111A (en) | 1992-11-25 |
KR900006333A (ko) | 1990-05-07 |
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ATS | Application withdrawn |